Abstract
For several years our laboratory has been engaged in the study of various aspects of bacteriophage P2, and in particular its behavior in the establishment of lysogeny. At the same time, another temperate bacteriophage, A, has been studied intensively in a number of laboratories, so much so that it has practically become paradigmatic in the study of lysogeny. We feel however that the continued detailed study of P 2 is very desirable because this phage differs from X in at least three properties, which we believe are of rather general biological interest: (a) P2 is not inducible, (b) P2 recombines with extremely low frequency, (c) P2 attaches itself at a variety of sites on the host-chromosome.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Anderson, T. F.: On the fine structure of the temperate bacteriophages P1, P2 and P22. Proc. Eur. Reg. Conf. on Electron Microscopy, Delft 1960, Vol. II, p. 1008–1011.
Bertani, G.: Lysogeny. Advanc. Virus Res. 5, 151–193 (1958).
Bertani, G.: Multiple lysogeny from single infection. Virology 18, 131–139 (1962).
Bertani G., and E. Six: Inheritance of prophage P2 in bacterial crosses. Virology 6, 357–381 (1958).
Bertani G., B. Torheim, and T. Laurent: Multiplication in Serratia of a bacteriophage, originating from Escherichia coli: lysogenization and host-controlled variation. Virology 32, 619–632 (1967).
Calef, E.: Mapping of integration and excision crossovers in superinfection double lysogens for phage lambda in Escherichia coli. Genetics 55, 547–556 (1967).
Campbell, A.: Episomes. Advanc. Genet. 11, 101–145 (1962).
Campbell, A.: The steric effect in lysogenization by bacteriophage lambda. II. Chromosomal attachment of the b2 mutant. Virology 27, 340–345 (1965).
Fischer-Fantuzzi, L.: Integration of λ and λ b2 genomes in nonimmune host bacteria carrying a A cryptic prophage. Virology 32, 18–32 (1967).
Kaiser, A. D., and D. Hogness: The transformation of Escherichia coli with deoxyribonucleic acid isolated from bacteriophage λ dg. J. molec. Biol. 2, 392–415 (1960).
Kelly, B.: Localization of P2 prophage in two strains of Escherichia coli. Virology 19, 32–39 (1963).
Kelly, B. L., and M. G. Sunshine: Association of temperate phage P2 with the production of histidine negative segregants by Escherichia coli. Bioch. biophys. Res. Commun 28, 237–243 (1967).
Mandel, M.: Infectivity of phage P2 DNA in presence of helper phage. Molec. Gen. Genet. 99, 88–96 (1967).
Sasaki, I., and G. Bertani: Growth abnormalities in Hfr-derivatives of Escherichia coli strain C. J. gen. Microbiol. 40, 365–376 (1965).
Signer, E. R.: Recombination between coliphages λ and Φ 80. Virology 22, 650–651 (1964).
Signer, E. R., and J. R. Beckwith: Transposition of the lac region of Escherichia coli. III. The mechanism of attachment of bacteriophage 0 80 to the bacterial chromosome. J. molec. Biol. 22, 33–51 (1966).
Six, E.: Inheritance of prophage P2 in superinfection experiments. Virology 14, 220–233 (1961).
Six, E.: Affinity of P2 rd l for prophage sites on the chromosome of Escherichia coli strain C. Virology 19, 375–387 (1963).
Six, E.: Specificity of P2 for prophage site I on the chromosome of Escherichia coli strain C. Virology 29, 106–125 (1966).
Taylor, A. L., and M. S. Thoman : The genetic map of Escherichia coli K-12. Genetics 50, 659–677 (1964).
Zichichi, M. L., and G. Kellenberger: Two distinct functions in the lysogenization process: the repression of phage multiplication and the incorporation of the prophage in the bacterial genome. Virology 19, 450–460 (1963).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1968 Springer-Verlag Berlin · Heidelberg
About this paper
Cite this paper
Bertani, G. (1968). Prophage Attachment and Detachment: Comparison of Phages P2 and λ . In: Wittmann, H.G., Schuster, H. (eds) Molecular Genetics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87534-2_17
Download citation
DOI: https://doi.org/10.1007/978-3-642-87534-2_17
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-04276-1
Online ISBN: 978-3-642-87534-2
eBook Packages: Springer Book Archive