Specific Antigens Produced by Oncogenic Viruses

  • Karl Habel
Part of the Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer book series (RECENTCANCER, volume 6)


Although it has been known for many years that certain viruses have something to do with tumor induction, in most instances there has been no specific evidence that the individual tumor cell had been directly transformed by a given virus. This sort of evidence was available only in the case of those RNA viruses, such as the avian leukoses, where the infected transformed cell continues to produce infectious virus. In the DNA virus-induced tumors, which are frequently free of infectious virus, there was no easy, direct way of establishing the etiological relationship. However, with the discovery in recent years that virus-induced tumors contain specific new antigens, a ready means of identification became available. There is good reason to believe that these antigens will be present in all virus-induced tumors, since one type or another has been found in all classes of tumors thus far adequately examined.


Viral Antigen Oncogenic Virus Tumor Challenge Complement Fixation Test Rous Sarcoma Virus 
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© Springer-Verlag New York Inc. 1966

Authors and Affiliations

  • Karl Habel
    • 1
  1. 1.United States Department of Health, Education, and Welfare, Public Health Service, National Institute of Allergy and Infectious Diseases, Laboratory of Biology of VirusesNational Institutes of HealthBethesdaUSA

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