Epigenetic Factors in the Neoplastic Response to Polyoma Virus
One could hardly speak of epigenetic matters before an audience at the University of Chicago without taking cognizance of the outstanding contributions that have come from that institution to the field of epigenetics. Among them, and quite relevant to the work described in this report, are the classical works of Dr. F. R. Lillie and Dr. Hsi Wang on the formation of feathers. In a series of experiments that lead to the delineation of the specific morphogenetic functions of the epithelial and the mesenchymal components of feather follicles (1), Dr. Lillie and Dr. Wang developed a pattern of analysis that has found increasing use in developmental biology, and is beginning to find application in experimental oncology. It is safe to predict that the debt of oncologists to those original investigations will continue to increase.
KeywordsPhenol Recombination Penicillin Trypsin Sine
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