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Transformation of Human Cells by Oncogenic Virus SV40

  • Anthony J. Girardi
  • Fred C. Jensen
Part of the Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer book series (RECENTCANCER, volume 6)

Abstract

To date, the only viruses that have been shown capable of transforming human cells in vitro are Simian Virus 40 (13, 16, 20, 24) and a hybrid strain or adenovirus type 7-SV40 (strain LLE-46) (4). This latter virus is a human strain of adenovirus which has apparently acquired a portion of the SV40 genome during laboratory passage. By currently accepted standards, infection of human tissue with Rous sarcoma or wart viruses has not led to transformation.

Keywords

Infectious Virus Simian Virus Contact Inhibition Virus Yield Adenovirus Type 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1966

Authors and Affiliations

  • Anthony J. Girardi
    • 1
  • Fred C. Jensen
    • 1
  1. 1.The Wistar InstitutePhiladelphiaUSA

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