Advertisement

Endokarditis durch Candida parapsilosis

  • H. J. Scholer
  • F. Gloor
  • L. Dettli

Zusammenfassung

Die vorliegende Beobachtung einer Candida-Endokarditis nach Zahnextraktionen liefert ein Beispiel dafür, daß Hefen von äußerst geringer Virulenz vorgeschädigte Herzklappen besiedeln und tödliche Sepsis verursachen können, wenn ihnen der Zugang ins Blut gleichsam gebahnt wird. Sie dokumentiert ferner, anscheinend zum ersten Male, eine durch klinische Behandlung erworbene Resistenz gegen Amphotericin B.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. 1.
    Caplan, H.: Monilial (Candida) endocarditis following treatment with antibiotics. Lancet 1955II, 957–958.CrossRefGoogle Scholar
  2. 2.
    Cassels, D., and P. Steiner: Mycotic endocarditis. Amer. J. Dis. Child. 67, 128–138 (1944).Google Scholar
  3. 3.
    Conn, N. K., G. P. Crean, A. F. Macabe and N. Mclean: Systemic Candidiasis and endocarditis due to C. tropicalis. Brit. med. J. 1959I, 944–947.Google Scholar
  4. 4.
    Drouhet, E.: Action de l’amphotéricine B dans les mycoses profondes. Etude mycologique, clinique et thérapeutique de 15 observations. Sem. Hôp. (Paris) 37, 101–121 (1961).Google Scholar
  5. 5.
    Fischer, E.: Die zahlenmäßige Häufigkeit der verschiedenen Hefen im mykologischen Untersuchungsmaterial. Schweiz. Z. Path. 18, 1–7 (1955).Google Scholar
  6. 6.
    Geiger, A. J., H. A. Wenner, H. D. Axilord and S. H. Durlacher: Mycotic endocarditis and meningitis. Report of a case due to Monilia albicans. Yale J. Biol. Med. 18, 259–268 (1945–1946).Google Scholar
  7. 7.
    Harrell, E. R., and G. R. Thompson: Systemic candidiasis (moniliasis) complicating treatment of bacterial endocarditis (with review of literature and report of apparent cure of one case with parenteral mycostatin). Ann. intern. Med. 48, 207–215 (1958).Google Scholar
  8. 8.
    Heymer, T., and R. Doepfmer: Über die Pilzflora der Mundhöhle. Arch. klin. exp. Derm. 204, 374–383 (1957).Google Scholar
  9. 9.
    Hyun, B. H., E. A. Dawson and R. E. Pence: Bacterial and mycotic endocarditis following cardiac surgery. J. thorac. Surg. 35, 298–304 (1958).PubMedGoogle Scholar
  10. 10.
    Hyun, B. H., E. A. Dawson and R. E. Pence and F. C. Collier: Mycotic endocarditis following intracardiac operations. Report of four cases. New Engl. J. Med. 263, 1339–1341 (1960).Google Scholar
  11. 11.
    Joachim, H., and S. H. Polayes: Subacute endocarditis and systemic mycosis (Monilia) J Amer. med. Ass. 115, 205–208 (1940).CrossRefGoogle Scholar
  12. 12.
    Kay, J. H., S. Bernstein, D. Feinstein and M. Biddle: Surgical cure of Candida albicans endocarditis with open-heart surgery. New Engl. J. Med. 264, 907–910 (1961).Google Scholar
  13. 13.
    Koelle, W. A., and B. H. Pastor: Candida albicans endocarditis after aortic valvulotomy. New Engl. J. Med. 255, 997–999 (1956).Google Scholar
  14. 14.
    Köhlmeier, W.: Zur Kenntnis der Candidainfektionen. Klin. Med. 8, 54–61 (1953).Google Scholar
  15. 15.
    Kunstadter, R. H., H. Mclean and J. Greengard: Mycotic endocarditis due to Candida albicans. J. Amer. med. Ass. 149, 829–832 (1952).CrossRefGoogle Scholar
  16. 16.
    Littman, M. L., M. A. Pisano and R. M. Lancaster: Induced resistance of Candida species to nystatin and amphotericin B. Antibiot. Ann. 1957/58, 981–987.Google Scholar
  17. 17.
    Louria, D. B., and P. Dineen: Amphotericin B in treatment of disseminated moniliasis. J. Amer. med. Ass. 174, 273–279 (1960).CrossRefGoogle Scholar
  18. 18.
    Luttgens, W. F.: Endocarditis in “Maine Line” opium addicts. Arch. intern. Med. 83, 653–664 (1949).Google Scholar
  19. 19.
    Merchant, R. K., D. B. Louria, P. H. Geisler, J. H. Edgcomb and J. P. Utz: Fungal endocarditis: review of the literature and report of three cases. Ann. intern. Med. 48, 242–266 (1958).PubMedGoogle Scholar
  20. 20.
    Niel, K.: Zur Klinik der Candidainfektionen. Klin. Med. 8, 49–54 (1953).Google Scholar
  21. 21.
    Pasternack, J. G.: Subacute monilia endocarditis, a new clinical and pathologic entity. Amer. J. clin. Path. 12, 496–505 (1942).Google Scholar
  22. 22.
    Pearl, M. A., and H. Sidransky: Candida endocarditis. Two new cases, with a review of twelve cases previously reported. Amer. Heart J. 60, 345–353 (1960).PubMedCrossRefGoogle Scholar
  23. 23.
    Persellin, R. H., O. M. Haring and F. J. Lewis: Fungal endocarditis following cardiac surgery. Ann. intern. Med. 54, 127–134 (1961).PubMedGoogle Scholar
  24. 24.
    Rieth, H.: Untersuchungen zur Hefediagnostik in der Dermatologie. Arch. klin. exp. Derm. 207, 413–430 (1958).Google Scholar
  25. 25.
    Skobel, P., D. Jorke U. G. Schabinski: Akute generalisierte Mykose. Sepsis durch Candida pseudotropicalis. Munch. med. Wschr. 97, 194–197 (1955).Google Scholar
  26. 26.
    Sorensen, L. J., E. G. Mcnall and T. H. Sternberg: The development of strains of Candida albicans and Coccidioides immitis, which are resistant to amphotericin B. Antibiot. Ann. 1958/59, 920–923.Google Scholar
  27. 27.
    Stout, H. A., and J. F. Pagano: Resistance studies with nystatin. Antibiot. Ann. 1955/56, 704–710.Google Scholar
  28. 28.
    Utz, J. P., and A. Treger: The current status of chemotherapy of systemic fungal diseases. Ann. intern. Med. 51, 1220–1229 (1959).PubMedGoogle Scholar
  29. 29.
    Utz, J. P., and A. Treger V. T. Andriole and C. W. Emmoxs: Chemotherapeutic activity of X-5079C in systemic mycoses of man. Amer. Rev. resp. Dis. 84, 514–528 (1961).Google Scholar
  30. 30.
    Utz, J. P., and A. Treger W. C. Roberts, T. Cooper, H. M. Kravetz and V. T. Andriole: Candida endocarditis: an emerging peril in cardiovascular surgery. Ann. intern. Med. 54, 1058 (1961).Google Scholar
  31. 31.
    Wikler, A., E. G. Williams, E. D. Douglass, C. W. Emmons and R. C. Dunn: Mycotic endocarditis: report of case. J. Amer. med. Ass. 119, 333–336 (1942).CrossRefGoogle Scholar
  32. 32.
    Wolfe, E. I., and F. W. Henderson: Mycotic endocarditis, report of a case. J. Amer. med. Ass. 147, 1344–1347 (1951).CrossRefGoogle Scholar
  33. 33.
    Wolff, O. H., B. W. Petty, R. Astley and J. M. Smellie: Thrush oesophagitis with pharyngeal incoordination treated with hydroxystilbamidine. Lancet 1955 I, 991–995.CrossRefGoogle Scholar
  34. 34.
    Zimmerman, L. E.: Candida and aspergillus endocarditis. Arch. Path. 50, 591–605 (1950).Google Scholar

Copyright information

© Springer-Verlag OHG. Berlin · Göttingen · Heidelberg 1963

Authors and Affiliations

  • H. J. Scholer
    • 1
  • F. Gloor
    • 2
  • L. Dettli
    • 3
  1. 1.Abteilung für experimentelle MedizinF. Hoffmann-La Roche & Co. A.G.BaselSchweiz
  2. 2.Pathologische-anatomische AnstaltUniversität BaselSchweiz
  3. 3.Medizinische Universitätsklinik BaselSchweiz

Personalised recommendations