Seizures and Status Epilepticus

  • Paul Ellis Marik


Status epilepticus (SE) is a term used to describe continuous seizures lasting at least 5 minutes or two or more discrete seizures between which there is incomplete recovery of consciousness. Some patients have no observable, repetitive motor activity, and the detection of ongoing seizures requires electroencephalography. Convulsive SE has many complications including hypertension, cardiac arrhythmias, hyperthermia, vomiting with aspiration, hyperglycemia, metabolic acidosis, injuries including vertebral and other fractures, and rhabdomyolysis with renal failure. Mortality caused by SE itself is approximately 2%; however, the overall mortality is approximately 30%, owing to the illness causing SE.


Status Epilepticus Migraine With Aura Central Nervous System Infection Refractory Status Epilepticus Convulsive Status Epilepticus 
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Selected References

  1. 1.
    Lowenstein DH, Alldredge BK. Status epilepticus. N Engl J Med. 1998; 338:970–976.PubMedCrossRefGoogle Scholar
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    Treiman DM, Meyers PD, Walton NY. A comparison of four treatments for generalized convulsive status epilepticus. Veterans Affairs Status Epilepticus Cooperative Study Group. N Engl J Med. 1998;339:792–798.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag New York, Inc. 2001

Authors and Affiliations

  • Paul Ellis Marik
    • 1
  1. 1.Critical Care MedicineMercy Hospital of PittsburghPittsburghUSA

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