Thyroid Diseases in the Critically III
Since the 1960s, it has been known that serum thyroid hormone levels drop during starvation and illness. In mild illness, this involves only a decrease in serum T3 levels. However, as the severity of the illness increases, there is a drop in both T3 and T4. This decrease in thyroid hormone level is seen in starvation, sepsis, surgery, myocardial infarction, transplantation, and in fact, probably any severe illness. Based on the premise that patients with these abnormalities are not hypothyroid despite the low hormone levels in blood, the condition has been called the sick euthyroid syndrome (SES). However, some experts in the field believe that some of these patients may in fact have tissue hypothyroidism and prefer the designation of nonthyroidal illness syndrome.
KeywordsThyroid Hormone Thyroid Hormone Level Multinodular Goiter Relative Adrenal Insufficiency Thyroid Storm
Unable to display preview. Download preview PDF.