Liver Failure and Jaundice in the Intensive Care Unit
Liver disease has two major components: hepatocyte failure and portal hypertension. The clinical picture of chronic liver disease is frequently dominated by the compilations of portal hypertension. On the other hand, the clinical picture of acute/fulminant hepatic failure is dominated by hepatocyte failure (Table 28–1). Fulminant hepatic failure (FHF) is potentially reversible and must be distinguished from chronic liver failure, an irreversible condition that develops over months to years. Patients with FHF are best managed in tertiary care facilities that have extensive experience in treating such patients, with facilities for orthotopic liver transplantation.
KeywordsPortal Hypertension Hepatic Encephalopathy Orthotopic Liver Transplantation Acute Liver Failure Fulminant Hepatic Failure
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