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Tolerable Mutations

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Abstract

The previous chapter pointed out that the functionally critical parts of a molecule have not changed much throughout the history of evolution. This is because mutations affecting these parts of a molecule have efficiently been eliminated by natural selection. Nevertheless, when the amino acid sequence of homologous polypeptide chains from diverse species are compared, amino acid substitutions at a varying number of sites are noted. Those mutations which have been permitted to accompany the successive processes of speciation shall be called tolerable mutations. What is the nature of these mutations which have been tolerated by natural selection? Some mutations accompanied the process of speciation merely because they were harmless. They are then neutral mutations. Others have been chosen actively by natural selection because they offered definite advantage over their wild-type counterparts. They shall be defined as favored mutations.

Keywords

  • Natural Selection
  • Gene Locus
  • Null Allele
  • Color Vision
  • Neutral Mutation

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© 1970 Springer Science+Business Media New York

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Ohno, S. (1970). Tolerable Mutations. In: Evolution by Gene Duplication. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-86659-3_7

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  • DOI: https://doi.org/10.1007/978-3-642-86659-3_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-86661-6

  • Online ISBN: 978-3-642-86659-3

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