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Forbidden Mutations

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Abstract

Only the amino acid sequence of a polypeptide chain defines its function. A polypeptide chain having a certain amino acid sequence serves as a subunit of immunoglobulin, while another polypeptide chain having a different amino acid sequence functions as a subunit of an enzyme, such as lactate dehydrogenase. It then follows that a change in the amino acid sequence of a polypeptide chain can deprive that polypeptide chain from the performance of its assigned function.

Keywords

  • Natural Selection
  • Polypeptide Chain
  • Disulfide Bridge
  • Peptide Chain
  • Heme Group

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© 1970 Springer Science+Business Media New York

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Ohno, S. (1970). Forbidden Mutations. In: Evolution by Gene Duplication. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-86659-3_6

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  • DOI: https://doi.org/10.1007/978-3-642-86659-3_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-86661-6

  • Online ISBN: 978-3-642-86659-3

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