Duodenogastric Reflux in Patients with Reflux Esophagitis Assessed by Radionuclide Technique
The composition of refluxed material is an important factor in the pathogenesis of reflux esophagitis. The effect of acid reflux into the esophagus has been well studied and its damage on the esophageal mucosa is clear. There are many studies that suggest the importance of bile salts and pancreatic juice as the cause of esophagitis [1–4], especially when both acid and bile-pancreatic secretion are present. Duodenogastric reflux is currently being widely studied, of interest being the precise role of this factor in the pathogenesis of reflux esophagitis. Increased duodenogastric reflux has been shown in patients with gastroesophageal reflux ; however, it is not clear whether duodenogastric reflux is greater in patients with different degrees of damage on the esophageal mucosa.
KeywordsGastroesophageal Reflux Lower Esophageal Sphincter Reflux Esophagitis Esophageal Mucosa Lower Esophageal Sphincter Pressure
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- 3.Schmid B, Tamosky G de, Leyden T (1981) Alkaline gastroesophageal reflux. Role in esophageal injury (Abstr). Gastroenterology 80:1275Google Scholar
- 4.Bremmer CG, Hamilton DG (1985) Barrett’s esophagus. Controversial aspects. In: DeMeester T, Skinner D (eds) Esophageal disorders. Raven, New YorkGoogle Scholar
- 8.Buxbauna KL (1982) Bile gastritis occurring after cholecystectomy. Am J Gastroent 77:305Google Scholar
- 9.Kalina T, Sjoberg J (1981) Bile reflux after cholecystectomy. Scand J Gastroenterol [Suppl 67] 16:153Google Scholar
- 10.Cortesini C, Marcuzzo G, Pucciani F (1985) Relationship between mixed acid-alkaline gastroesophageal reflux and esophagitis. Ital J Surg Sci 15:1–12Google Scholar
- 11.Stols DW, Murphy GM, Leigh Collis J (1974) Duodenogastric reflux and acid secretion in patients with symptomatic hiatal hernia. Scand J Gastroenterol 9:97Google Scholar