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Patterns of Autosomal Heterochromatin

  • A. Gropp
  • P. Citoler

Abstract

The relationship of chromocenters of interphase nuclei to the hetero-chromatin of metaphase chromosomes is well studied for the sex chromosomes of man and mammals (Ohno et al., 1959; Schmid, 1967; Tiepolo et al., 1967; Zakharov and Egolina, 1938). One of the most important implications of this relationship is the inactive-X hypothesis expressed by Lyon (1961). Genetic inactivation and heterochromatinization can be assumed to be characteristic features of one of the X-chromosomes in the female. Asynchronous late replication of the DNA is a further remarkable phenomenon shown by the X-heterochromatin.

Keywords

Metaphase Chromosome Interphase Nucleus Fibroblast Culture Labelling Pattern Male Fetus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1969

Authors and Affiliations

  • A. Gropp
    • 1
  • P. Citoler
    • 1
  1. 1.Abteilung für Cytopathologie und Cytogenetik des Pathologischen InstitutsUniversität BonnGermany

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