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Aspects of Altered Gene Expression in Heart Failure and Myocardial Hypertrophy

  • Michael Böhm
  • Erland Erdmann
Chapter

Abstract

The phenotype and the function of differentiated eukaryotic cells is determined by the functional condition of their proteins (ion channels, enzymes), the protein expression (transcriptional and post-transcriptional regulation), the protein biosynthesis (translation) and the underlying nucleotide sequence in the genetic code (possible mutation of the genome). Changes, which influence the functional properties and the structure of the cell, can occur at each of these levels.

Keywords

Sarcoplasmic Reticulum Altered Gene Expression Myocardial Hypertrophy Contractile Apparatus Intracellular Calcium Homeostasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • Michael Böhm
    • 1
  • Erland Erdmann
    • 1
  1. 1.Klinik III für Innere MedizinUniversität zu KölnKölnGermany

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