Calcium antagonists are frequently used in treatment of arterial hypertension and coronary heart disease. The three classes of substances used are dihydro-pyridine derivates, benzothiazepine derivates and phenylalkylamine derivates. Examples of the dihydropyridine derivates are nifedipine (1st generation) and newer substances of the so-called second generation (nitrendipine, nisoldipine, nicardipine, nimodipine, isradipine, felodipine, amlodipine). Of the benzothiazepine and derivates, diltiazem is used, and of the phenylalkylamine derivates, verapamil and gallopamil.
KeywordsHeart Failure Chronic Heart Failure Calcium Antagonist Dilate Cardiomyopathy Severe Heart Failure
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