RNA Synthesis in Growing Bone

Conference paper


This paper describes the preliminary results of an autoradiographic study of the pattern of RNA synthesis in cells which are associated with growing bone surfaces. The system studied is the periosteal surface of the shaft of the femur of young actively growing rabbits aged about 2 weeks. A diagrammatic representation of this surface is shown in Fig. 1 a. The bone surface has characteristic loops typical of forming haversian systems. Osteoblasts line the surface of the bone and the haversian systems. The layer of cells behind the osteoblasts on the bone surface have been called preosteoblasts, a term also given to cells which are within the haversian canals but not on their surfaces. A layer of fibroblasts with typical elongated nuclei separates the osteogenic cellular layer from nearby muscle.


Bone Surface Cartilage Cell Periosteal Surface Haversian Canal Haversian System 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1966

Authors and Affiliations

  • M. Owen
    • 1
  1. 1.Medical Research CouncilBone-Seeking Isotopes Research Unit, The Churchill HospitalOxfordEngland

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