Abstract
Towards the end of puberty a profound change occurs in bone. This is so striking that it might, for want of a better term, be called “bone puberty”. There is as yet no clear correlation between this event and chronological age, cessation of growth, sexual maturation or bone age. Before bone puberty, bone has great reparative power and is in some respects plastic. For example, fracture union is rapid and non-union is rare; a tibia or femur can be lengthened four inches (10 cm.) or more following a simple transverse osteotomy and reconstitution of the defect occurs rapidly; the curve in idiopathic (spinal) scoliosis continues to progress; and imbalanced muscle pull produces bone malalignment.
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Rigal, W.M., Hunter, W.M. (1966). Sites and Mode of Action of Growth Hormone. In: Fleisch, H., Blackwood, H.J.J., Owen, M. (eds) Calcified Tissues 1965. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85841-3_49
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DOI: https://doi.org/10.1007/978-3-642-85841-3_49
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