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Eiweißdenaturierung

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Book cover Bausteine des Tierkörpers II

Part of the book series: Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse ((HOPPE-SEYLER,volume 4))

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Zusammenfassung

Obwohl Denaturierung in jedem Einzelfall leicht beschrieben werden kann, ist es schwer, eine allgemeingültige Definition zu geben. Neurath, Greenstein, Putnam und Erickson definieren Denaturierung1 als eine Modifikation der dem nativen Protein eigenen Struktur, die nicht durch Proteolyse verursacht ist und sich in Änderungen der chemischen, physikalischen oder biologischen Eigenschaften äußert. Putnam 2 hat später Denaturierung als Änderung in der räumlichen Lage der Atome ohne Hydrolyse von kovalenten Bindungen definiert. Keine dieser Definitionen befriedigt vollkommen, da man nicht die Hydrolyse von Dithiobindungen während des Denaturierungsvorganges ausschließen kann.

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Authors and Affiliations

  1. Bloomington, Indiana, USA

    Professor Dr. Felix Haurowitz

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  1. Professor Dr. Felix Haurowitz
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E. Bayer H.-J. Bielig G. Blix H. Dörfel K. Felix F. G. Fischer S. Gardell W. Grab R. G. Haber E. Habermann K. Hannig F. Haurowitz W. E. van Heyningen J. Kimmig J. Meienhofer R. Michel W. Neumann I. Pendl J. Roche H. Schmid G. Schmidt W. Siedel R. Wehrmann H. Zahn

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Haurowitz, F. (1960). Eiweißdenaturierung. In: Bayer, E., et al. Bausteine des Tierkörpers II. Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85729-4_2

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  • DOI: https://doi.org/10.1007/978-3-642-85729-4_2

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