Abstract
Among the many metabolic factors involved in the pathogenesis of myocardial ischemia two principal groups may be distinguished:
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1
Disturbances leading to changes in the coronary arteries and in consequence to impairment of the coronary circulation. The most important alteration is sclerosis of the coronary arteries.
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2
Primary metabolic disorders of the myocardium, not necessarily involving coronary circulation.
Published in Cardiologia 40, 97–112 (1962).
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References
Constantinides, P., J. Booth and G. Carlson: Advanced atherosclerosis of the human type in the rabbit: A new experimental tool. Internationales Symposium über „Drugs affecting lipid metabolism“, Mailand, Juni 1960.
Bragdon, J. H.: Transfusion transfer of experimental atherosclerosis. Circulation 4, 466 (1951).
Schrade, W., R. Biegler and E. Böhle: Fatty acid distribution in the lipid fractions of healthy persons of different age, patients with atherosclerosis and patients with idiopathic hyperlipidemia. J. Arteriosclerosis Res. 1, 47 (1961).
Rutstein, D. D., E. F. Ingenito, J. M. Craig and M. Martinelli: Effects of linolenic and stearic acids on cholesterol-induced lipoid deposition in human aortic cells in tissue culture. Lancet 1, 545 (1958).
Fisher, H., and A. S. Feigenbaum: Essential fatty acids of normal and atherosclerotic aortas from chicken receiving differently saturated fats for three years. Nature 186, 85 (1960).
Gey, K. F., and A. Pletscher: Inability of refined corn oil to influence spontaneous arteriosclerosis of old hens. Nature 189, 491 (1961).
Böttcher, C. J. F., F. P. Woodford, C. Ch. Romeny-Wacher, E. Boelsma-Van Houte and C. M. Van Gent: Fatty acid distribution in lipids of the aortic wall. Lancet 1, 1378 (1960).
Böttcher, C. J. F., and C. M. Van Gent: Changes in the composition of phospholipids and of phospholipid fatty acids associated with atherosclerosis in the human aortic wall. J. Arteriosclerosis Res. 1, 36 (1961).
Zilversmit, D. B., and E. L. Mc Candless: Independence of arterial phospholipid synthesis from alterations in blood lipids. J. Lipid Res. 1, 118 (1959).
Zilversmit, D. B., P. H. Jordan, W. S. Henley and P. F. Ackerman: The synthesis of phospholipids in human atheromatous lesions. Circulation 23, 370 (1961).
Newman, H. A., and D. B. Zilversmit: Origin of various lipids in atheromatous lesions of rabbits. Circulation 20, 967 (1959).
Geer, J. G., H. G. McGill, J. P. Strong and R. L. Holman: Electron microscopy of human atherosclerotic lesions. Fed. Proc. 19, 15 (1960).
Werthessen, N. T., M. A. Nyman, R. L. Holman and J. P. Strong: In vitro study of cholesterol metabolism in the calf aorta. Circulat. Res. 4, 586 (1956).
Schwenk, E., and D. F. Stevens: Deposition of cholesterol in experimental rabbit atherosclerosis. Proc. Soc. exp. Biol. 103, 614 (1960).
Meyer, K.: Struktur und Biologie der Polysaccharidsulfate im Bindegewebe. In: Struktur und Stoffwechsel des Bindegewebes, Symposium an der Med. Universitätsklinik Münster (Westfalen). Stuttgart: Thieme 1959, S. 12.
Gillman, T., M. Hathorn and J. Penn: Micro-anatomy and reactions to injury of vascular elastic membranes and associated polysaccharides. In: Connective Tissue (herausg. R. E. Turnbridge). London: Blackwell 1957, S. 120.
Odeblad, E., and H. Boström: A quantitative autoradiographic study on the uptake of labelled sulphate in the aorta of the rabbit. Acta chem. scand. 7, 233 (1953).
Kirk, J. E.: Mucopolysaccharides of arterial tissue. In: The Arterial Wall (herausg. A. I. Lansing). Williams and Wilkins Company, 1959, S. 161.
Buck, R. C., and F. C. Heagy: Uptake of radioactive sulphur by various tissues of normal and cholesterol-fed rabbits. Canad. J. Biochem. 36, 63 (1958).
Hilz, H., und D. Usterman: Der Sulfatstoffwechsel der Gefäßwand in Beziehung zur Arteriosklerose und seine Beeinflussung durch Sexualhormone. Biochem. Z. 332, 376 (1960).
Kowalewski, K.: Uptake of radiosulphate by mucopolysaccharides of aorta in cholesterol-fed cockerels. Proc. Soc. exp. Biol. 101, 356 (1959).
Rinehart, J. F., and L. D. Greenberg: Arteriosclerotic lesions in pyridoxine-deficient monkeys. Amer. J. Path. 25, 481 (1949).
Mushett, C. W., and G. A. Emerson: Arteriosclerosis in pyridoxine-deficient monkeys and dogs. Fed. Proc. 15, 526 (1956).
Dyrbye, M. O.: Studies on the metabolism of the mucopolysaccharides of human arterial tissue by means of S35, with special reference to changes related to age. J. Gerontol. 14, 32 (1959).
Raab, W.: The adrenergic-cholinergic control of cardiac metabolism and function. In: Fortschritte der Kardiologie (herausg. R. Hegglin), Vol. 1. Basel: Karger 1956, S. 65.
Gerola, A., H. Feinberg and L. N. Katz: Role of catecholamines on energetics of the heart and its blood supply. Amer. J. Physiol. 196, 394 (1959).
Berne, R. M.: Effect of epinephrine and norepinephrine on coronary circulation. Circulat. Res. 6, 644 (1958).
Szakács, J. E., and A. Cannon: 1-Norepinephrine myocarditis. Amer. J. clin. Path. 30, 425 (1958).
Szakács, J. E., and B. Mehlman: Pathologic changes induced by 1-norepinephrine: quantitative aspects. Amer. J. Cardiol. 5, 619 (1960).
Maling, H. M., B. Highman and E. C. Thompson: Some similar effects after large doses of catecholamines and myocardial infarction in dogs. Amer. J. Cardiol. 5, 628 (1960).
Melville, K. I., and H. E. Shister: Cardiac responses to epinephrine and norepinephrine during prolonged cholesterol and high fat feeding in rabbits. Amer. J. Cardiol. 4, 391 (1959).
Gazes, P. C., J. A. Richardson and E. F. Woods: Plasma catecholamine concentrations in myocardial infarction and angina pectoris. Circulation 19, 657 (1959).
Kako, K., J. D. Choudhury and R. J. Bing: Possible mechanism of the decline in mechanical efficiency of the isolated heart. J. Pharmacol. exp. Therap. 130, 46 (1960).
Danforth, H., F. B. Ballard, K. Kako, J. D. Choudhury and R. J. Bing: Metabolism of the heart in failure. Circulation 21, 112 (1960).
Kako, K., A. Chrysohou and R. J. Bing: Storage of catecholamines in the heart. Effect of amine oxidase inhibitors. Circulation Res. 9, 295 (1961).
Pletscher, A., K. F. Gey und P. Zeller: Monoaminoxydase-Hemmer: Chemie, Biochemie, Pharmakologie, Klinik. In: Fortschritte der Arzneimittelforschung (herausg. E. Jucker), Vol. 2. Basel: Birkhäuser 1960, S.417.
Zbinden, G.: Inhibition of experimental myocardial necrosis by the monoamine oxidase inhibitor isocarboxazid (Marplan). Amer. Heart J. 60, 450 (1960).
Selye, H.: Elektrolyte, Stress und Herznekrose. Basel: Benno Schwabe & Co. 1960.
Melville, K. I., and B. Korol: Cardiac drug responses and potassium shifts. Studies on the interrelated effects of drugs on coronary flow, heart action and cardiac potassium movement (part I and II). Amer. J. Cardiol. 2, 81, 189 (1958).
Pletscher, A.: Einfluß von Isopropyl-isonikotinsaurehydrazid auf den Katecholamingehalt des Myokards. Experientia 14, 73 (1958).
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Pletscher, A. (1962). Metabolic causes of myocardial ischemia. In: Annals of Life Insurance Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85611-2_3
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