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Klinische Immunologie

  • Conference paper
Verhandlungen der Deutschen Gesellschaft für innere Medizin

Part of the book series: Verhandlungen der Deutschen Gesellschaft für innere Medizin ((VDGINNERE,volume 89))

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Zusammenfassung

Ätiologie und Pathogenese des systemischen Lupus erythematosus (SLE) sind bis heute ungeklärt. Immunologische Faktoren scheinen dabei aber eine zentrale Rolle zu spielen, da vielfach der Nachweis von abnormen immunregulatorischen Mechanismen und einer B-Zellhyperaktivität gelungen ist, die für das Auftreten von Autoantikörpern verantwortlich sind (s. Tabelle 1). Die Charakterisierung immunregulatorischer T-Zellsubpopulationen mit monoklonalen Antikörpern hat neue Möglichkeiten der Analyse des Immunsystems eröffnet [2]. In der vorliegenden Studie weisen wir mittels T-Zellphänotypisierung nach, daß Patienten mit SLE ein klinisch wie immunologisch heterogenes Krankengut darstellen.

Herrn Prof. Dr. R. Eberl, Wien, zum 60. Geburtstag gewidmet

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Author information

Authors and Affiliations

  1. 2. Med. Univ.-Klinik Wien, Österreich

    J. S. Smolen & A. Wolf

  2. Arthritis and Rheumatism Branch, NIADDK, NIH, Bethesda, Maryland, USA

    A. D. Steinberg & T. M. Chused

  3. Sidney Farber Cancer Inst., Boston, Massachussetts, USA

    C. Morimoto, E. L. Reinherz & S. A. Schlossman

  4. II. Med. Univ.-Klinik Wien, Austria

    A. Wolf

  5. ARB, NIADDK, NIH, Bethesda, Maryland, USA

    A. D. Steinberg

  6. Inst. für Blutgruppenserologie der Univ. Wien, Austria

    W. R. Mayr

  7. ARB, NIADDK, NIH, Bethesda, Maryland, USA

    J. H. Klippel

  8. II. Med. Univ.-Klinik Wien, Austria

    O. Scherak

  9. ARB, NIADDK, NIH, Bethesda, Maryland, USA

    D. L. Mann & R. Davis

  10. II. Med. Univ.-Klinik, Wien, Austria

    J. S. Smolen

  11. Inst. für Immunologie der Univ. Wien, Austria

    C. Müller

  12. II. Med. Univ.-Klinik Wien, Austria

    C. Zielinsky

  13. Inst. für Immunologie der Univ. Wien, Austria

    J. Mannhalter & G. Zlabinger

  14. II. Med. Abt., Kaiser Franz-Josef-Spital Wien, Austria

    B. Kaik

  15. II. Med. Univ.-Klinik Wien, Austria

    A. Wolf

  16. Inst. für Immunologie der Univ. Wien, Austria

    M. Eibl

  17. Med. Klinik Tübingen, Deutschland

    J. H. Bartel

  18. DRK-Krankenhaus Hamburg, Deutschland

    M. Kirchhof

  19. Med. Klinik Tübingen, Deutschland

    W. Dölle & P. A. Berg

  20. Inst. und Poliklinik für klin. Immunologie und Rheumatologie der Univ. Erlangen-Nürnberg, Deutschland

    F. E. Krapf & B. Manger

  21. Behringwerke AG Marburg, Deutschland

    P. Krauledat

  22. Inst. und Poliklinik für klin. Immunologie und Rheumatologie der Univ. Erlangen-Nürnberg, Deutschland

    G. Lösch & J. R. Kalden

  23. Med. Klinik der Univ. Tübingen, Deutschland

    P. A. Berg, G.-J. Diao & N. Brattig

  24. II. Med. Klinik der Univ. Kiel, Deutschland

    W. Kayser

  25. Inst. für Klin. Immunologie und Tranfusionsmedizin Gießen, Deutschland

    C. Mueller-Eckhardt

  26. Inst. für Med. Mikrobiologie der Univ. Gießen, Deutschland

    S. Bhakdi

  27. II. Med. Klinik der Univ. Kiel, Deutschland

    K. Ebert-Kayser

  28. Med. Univ.-Klinik Tübingen, Deutschland

    R. Klein

  29. Med. Univ.-Klinik Würzburg, Deutschland

    B. Maisch & K. Kochsiek

  30. Med. Univ.-Klinik Tübingen, Deutschland

    P. A. Berg

  31. Med. Univ.-Klinik Würzburg, Deutschland

    I. O. Auer, A. Röder & J. Froehlich

  32. Med. Univ.-Klinik Freiburg, Deutschland

    F. Kluge, P. Hoppe-Seyler & W. Gerok

  33. Inst. für Med. Virologie imd Immunologie Essen, Deutschland

    H. Grosse-Wilde

  34. Immunolog. Labor, Med. Univ.-Klinik Bonn-Venusberg, Deutschland

    M. Lüttkenhorst, R. E. Schmidt, D. Niese, U. Winke & J. Sennekamp

  35. Abt. Pulmologie, Deutschland

    U. Costabel

  36. Abt. Hämatologie-Onkologie, Deutschland

    K. J. Bross

  37. Abt. Pulmologie, Med. Univ.-Klinik Freiburg, Deutschland

    D. Burger, E. Carlgren & H. Matthys

  38. Abt. für Pneumologie, Deutschland

    M. Rust

  39. Abt. für Haematologie und Onkologie, Deutschland

    L. Bergmann & P. S. Mitrou

  40. Abt. für Pneumologie des Zentrums der Inneren Medizin des Klinikums der Univ. Frankfurt, Deutschland

    T. Kühn & J. Meier-Sydow

  41. Abt. 3, Med. Univ.-Klinik Tübingen, Deutschland

    G. A. Müller & M. Gebhardt

  42. Patholog. Inst. Tübingen, Deutschland

    D. Ziegenhagen

  43. Abt. 2, Immunolog. Labor, Med. Klinik Tübingen, Deutschland

    C. Müller

  44. Inst, für Anthropologie und Humangenetik Tübingen, Deutschland

    J. Kömpf

  45. Patholog. Inst. Tübingen, Deutschland

    A. Bohle

  46. Abt. 2, Immunolog. Labor, Med. Klinik Tübingen, Deutschland

    P. Wernet

  47. I. Med. Klinik und Poliklinik der Univ. Mainz, Deutschland

    A. Knuth, W. Dippold & K.-H. Meyer zum Büschenfelde

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  1. J. S. Smolen
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Editor information

Editors and Affiliations

  1. Kliniken der Landeshauptstadt Wiesbaden, Wiesbaden, D-6200, Deutschland

    Bernhard Schlegel

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© 1983 J. F. Bergmann Verlag, München

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Smolen, J.S. et al. (1983). Klinische Immunologie. In: Schlegel, B. (eds) Verhandlungen der Deutschen Gesellschaft für innere Medizin. Verhandlungen der Deutschen Gesellschaft für innere Medizin, vol 89. J.F. Bergmann-Verlag. https://doi.org/10.1007/978-3-642-85456-9_23

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  • DOI: https://doi.org/10.1007/978-3-642-85456-9_23

  • Publisher Name: J.F. Bergmann-Verlag

  • Print ISBN: 978-3-8070-0335-1

  • Online ISBN: 978-3-642-85456-9

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