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Antibradykarde Stimulation: Prognose, Hämodynamik, Indikationen

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Zusammenfassung

Die antibradykarde, elektrische Therapie des Herzens stellt heute eine der effektivsten Behandlungsmethoden der modernen Kardiologie dar. Ihre Vorteile gegenüber einer medikamentösen Therapie werden vor allem bei höhergradigen AV-Blockierungen mit und ohne Adams-Stokes-Symptomatik deutlich. So war vor Beginn der Schrittmacherära die Manifestation einer Adams-Stokes-Symptomatik und/oder die Entwicklung eines kompletten AV-Blocks bei einer Letalität von etwa 50% im ersten Jahr (Penton, 1956; Edhag, 1976) mit einer sehr ernsten Prognose behaftet; mit der Einführung der Schrittmachertherapie wurde sie entscheidend verbessert.

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Literatur

  1. Abinader EG, Goldhammer E, Hassan A (1987). The significance of properly timed ventricular systole on diastolic mitral regurgitation occuring in complete heart block. PACE 10 (PartIII):630CrossRefGoogle Scholar
  2. Adolph RJ, Holmes JC, Fukusumi H (1968). Hemodynamic studies in patients with chronically implanted pacemakers. Am Heart J 76:829PubMedCrossRefGoogle Scholar
  3. Aguirre JM, Ruiz de Azua E, Molinero E, Segastagoitia D, Abrispueta J, Iriark M (1987). Hemodynamic response to isotonic exercise of rate responsive pacemaker Aktivitrax vs VVI. PACE 10:1205CrossRefGoogle Scholar
  4. Akhtar M, Damato AN, Batsford WP, Ruisku JN, Ogunkelu JB (1975). A comparative analysis of antegrade and retrograde conduction intervals in man. Circulation 52:766PubMedGoogle Scholar
  5. Ahktar M, Gilbert CJ, Wolf FG, Schmidt DH (1979). Retrograde conduction in the His-Purkinje system. Analysis of routes of impulse propagation using His and right bundle branch recordings. Circulation 59:1952Google Scholar
  6. Albani E, Amati PC, Destro A, Querze M, Rossi F, Antonioli GE (1983). Echocardiographic parameters in DDD A-V sequential paced patients. PACE 6:A-76Google Scholar
  7. Alicandri C, Fouad FM, Tarazi RC, Castle L, Morant V (1978). Three cases of hypotension and syncope with ventricular pacing: possible role of atrial reflexes. Am J Cardiol, 42:137PubMedCrossRefGoogle Scholar
  8. Alpert MA, Katti SK (1982). Natural history of high-grade atrioventricular block following permanent pacemaker implantation. J Chron Dis 35:431CrossRefGoogle Scholar
  9. Alpert MA, Curtis JJ, SanFelippo JF, Flaker GC, Walls JT, Mukerji V, Villarreal D, Katti SK, Madigan NP, Krol RB (1986). Comparative survival after permanent ventricular dual chamber pacing for patients with chronic high degree atrioventricular block with and without preexistent congestive heart failure. J Am Coll Cardiol 7:925PubMedCrossRefGoogle Scholar
  10. Alt E, Wirtzfeld A, Klein G (1983). Hämodynamische Ergebnisse bei ventrikulärer und physiologischer Stimulation. Herz Kreisl 2:31Google Scholar
  11. Alt E, Völker R, Wirtzfeld A, Ulm K (1985). Survival and follow-up after pacemaker implantation: a comparison of patients with sick sinus syndrome, complete heart block, and atrial fibrillation. PACE 8:849PubMedCrossRefGoogle Scholar
  12. Alt E, Theres H, Heinz M, Matula M, Thilo R, Blömer H (1988). A new rate responsive pacemaker system optimized by combination of two sensors. PACE 11:1119PubMedCrossRefGoogle Scholar
  13. Alt E, Völker R, Högl B, MacCarter D (1988). Kardiopulmonale Belastungstests unter frequenzvariabler Stimulation: Ein Vergleich von Activitrax-und Nova-MR-Schrittmachern zu VVI-/AAI-Stimulation. Z Kardiol 77:456PubMedGoogle Scholar
  14. Amikam S, Lemer J, Roguin N, Peleg H, Riss E (1976). Long-term survival of elderly patients after pacemaker implantation. Am Heart J 91:445PubMedCrossRefGoogle Scholar
  15. Anderson KM, Moore AA (1986). Sensors in pacing. PACE 9 (PartII):954PubMedCrossRefGoogle Scholar
  16. Anderson KM, Moore AA (1987). Cardiac sensors for hemodynamic assessment. PACE 10(PartII):634Google Scholar
  17. Anderson K, Humen D, Klein G, Brumwell D, Huntley S (1983). A rate variable pacemaker which automatically adjusts for physical activity. PACE, 3:A-12Google Scholar
  18. Antonioli GE, Albani E, Amati PC, Destro A, Marzaloni M, Sermasi S, Pesaresi A, Percoco GF, Ferrari C, Zanardi F, D Agostino, Toselli T, Rossi F (1988). 2D and Doppler echocardiography in dual-chambered paced patients. PACE 11 (Suppl):846Google Scholar
  19. Aroesty JM, Cohen SI, Morkin E (1974). Bradycardia-tachycardia syndrome: results in 28 patients treated with combined pharmacologic therapy and pacemaker implantation. Chest 66:257PubMedCrossRefGoogle Scholar
  20. Astrand I, Landegren J (1965). The effect of varying rate on physical work capacity in patients with complete heart block. Acta Med Scand 177:657PubMedCrossRefGoogle Scholar
  21. Attuel P, Pellerin D, Fernandez P, Quatre JM, Mugica J, Coumel P (1988). DDD pacing — an effective treatment modality for recurrent atrial arrhythmias. PACE 11 (Suppl):859CrossRefGoogle Scholar
  22. Ausubel K, Steingart RM, Shimshi M, Klementowicz P, Furman S (1985). Maintainance of exercise stroke volume during ventricular versus atrial synchronous pacing: role of contractility. Circulation 72(5): 1037PubMedCrossRefGoogle Scholar
  23. Bailer D, Hoeft A, Korb H, Wolpers HG, Zipfel J, Hellige G (1981). Basic physiological studies on cardiac pacing with special references to the optimal mode and rate after cardiac surgery. Thorac Cardiovasc Surgeon 29:168CrossRefGoogle Scholar
  24. Bailer D, Heilige G (1986a). The failing heart has a higher oxygen consumption during ventricular pacing compared to atrial pacing. In: Santini M, Pistolese M, Alliegro A (eds). Progress in clinical pacing. Rome, p325Google Scholar
  25. Baller D, Heilige G (1986b). Ventricular pacing increases coronary resistance in the failing heart at higher rates. In: Santini M, Pistolese M, Alliegro A (eds). Progress in clinical pacing. Rome, p343Google Scholar
  26. Bailer D, Wolpers, HG, Zipfel J, Bretschneider HJ, Hellige G (1988). Comparison of the effects of right atrial, right ventricular apex and atrioventricular sequential pacing on myocardial oxygen consumption and cardiac efficiency: a laboratory investigation. PACE 11:394CrossRefGoogle Scholar
  27. Barold S, Linhart J, Samet P (1968). Reciprocal heating induced by ventricular pacing. Circulation 38:330PubMedGoogle Scholar
  28. Bathen J, Hegrenes L, Skjaerpe T (1983). Pulsed doppler ultrasound for estimating blood flow in the aorta during cardiac pacing. PACE 6: A-87Google Scholar
  29. Baytte CK, Weale FE ( 1960). The use of P-wave for control of a pacemaker in heart block. Thorax, 15:177Google Scholar
  30. Bellinder G, Nordlander R, Pehrsson SK, Aström H (1986). Atrial pacing in the management of sick sinus syndrome: long-term observation for conduction disturbances and supraventricular tachyarrhythmias. Eur Heart J 7:105PubMedGoogle Scholar
  31. Bellocci F, Montenero S, Scabbia E, Zecchi P, Spampinato A, Nobile A (1988). Long-term follow-up of activity sensing rate responsive pacemaker. PACE 11 (Suppl) 798Google Scholar
  32. Benchimol A, Ellis J, Dimond G (1965). Hemodynamic consequences of atrial and ventricular pacing in patients with normal and abnormal hearts. Am J Med, 39:911PubMedCrossRefGoogle Scholar
  33. Benditt AG, Mianulli M, Fetter J, Benson DW, Dunnigan A, Molina E, Gornick CC, Almquist A (1987). Single chamber cardiac pacing with activity-initiated chronotropic response: evaluation by cardiopulmonary exercise testing. Circulation 75:184PubMedCrossRefGoogle Scholar
  34. Bennett TD, Olson WH, Bornzin GA, Baudino MD (1985). Alternative modes for physiological pacing. In: Gomez FP (ed) Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p577Google Scholar
  35. Bennett TD, Beck R, Erickson M (1987). Right ventricular dynamic pressure parameters for differentiation of supraventricular and ventricular rhythms. PACE 10(39):415Google Scholar
  36. Bergbauer M, Sabin G (1983). Hämodynamische Langzeitresultate der bifokalen Schrittmacherstimulation. Dtsch Med Wschr 108:545PubMedCrossRefGoogle Scholar
  37. Berkovits BV, Castellanos A, Lemberg L (1969). Bifocal demand pacing. Circulation (Suppl) 39: III 44Google Scholar
  38. Berkovits BV, Castellanos A, Dreifus LS, Lemberg L, Levy S, Mandel WJ, Obel P (1979). Double demand sequential pacing for the termination of paroxysmal reentry tachyarrhythmia. In: Meere CM (ed) Cardiac pacing. Proceedings of the VIth World Symposion on Cardiac Pacing. p. 6–21Google Scholar
  39. Bernstein AD, Camm AJ, Fletcher RD, Gold RD, Rickards AF, Smyth NPD, Spielman SR, Sutton R (1987). The NASPE/BPEG generic pacemaker code for antibradyarrhythmia and adaptive-rate pacing and antitachyarrhythmia devices. PACE 10 (Part I):794PubMedCrossRefGoogle Scholar
  40. Bernstein V, Roem C, Peretz DI (1971). Permanent pacemakers: 8-year follow-up study. Incidence and management of congestive cardiac failure and performance. Ann Intern Med 74:361Google Scholar
  41. Bertholet M, Demoulin JC, Fourny J, Kulbertus H (1983). Natural evolution of atrioventricular conduction in patients with sick sinus syndrome treated by atrial demand pacing. A study of 26 cases. Acta Cardiol 38:227Google Scholar
  42. Bevegard S, Johnsson B, Karlöf I, Lagergren H, Sowton E (1967). Effect of changes in ventricular rate and central pressures at rest and during exercise in patients with artificial pacemakers. Cardiovasc Res 1:21PubMedCrossRefGoogle Scholar
  43. Beyer J, Thorban S, Adt M, Hemmer W (1983). Physiological vs. VVI pacing: Its effect on cardiac output with different left ventricular compliance. PACE 6: A 84Google Scholar
  44. Blömer H., Wirtzfeld A, Delius W, Sebening H (1977). Das Sinusknotensyndrom. Straube, ErlangenGoogle Scholar
  45. Boccadamo R, Altamura G, Pistolese M (1982). Antiarrhythmic control of the brady-tachy syndrome by pacing. In: Feruglio G (ed) Cardiac pacing.Piccin, Padova, p507Google Scholar
  46. Bolli P, Müller FB, Linder L, Raine AE, Resink TJ, Erne P, Kiowski W, Ritz R, Bühler FR (1987). The vasodilator potency of atrial natriuretic peptide in man. Circulation 75:221PubMedCrossRefGoogle Scholar
  47. Bolt W, Buchter A, Grosser KD (1971). Die Leistungsbreite bei Patienten mit Herzschrittmachern. Verh Dtsch Ges Inn Med 77:457PubMedGoogle Scholar
  48. Braunwald E, Frahm CJ (1961). Studies on Starling’s law of the heart. Observations on the hemodynamic functions of the left atrium in man. Circulation 14:633Google Scholar
  49. Braunwald E, Sonnenblick EH, Ross J, Glick G, Epstein SE (1967). An analysis of the cardiac response to exercise. Circ Res XXI:44Google Scholar
  50. Breivik K, Ohm O, Segadal L (1979). Sick sinus syndrome treated with permanent pacemakers in 109 patients. Acta med Scand 206:153PubMedCrossRefGoogle Scholar
  51. Brockman SK (1963). Dynamic function of atrial contraction in regulation of cardiac performance. Am J Physiol 204:597PubMedGoogle Scholar
  52. Brockman SK (1966). Mechanism of the movements of the atrioventricular valves. Am J Cardiol, 17:682PubMedCrossRefGoogle Scholar
  53. Brofman P, Rossi P, Loures D, Ribeiro E, Ardito R, Braile D, Greco O, Lorga A (1987). Rate responsive pacemaker in Chagas disease. PACE 10:1208Google Scholar
  54. Buckingham Th, Woodruff R, Pennington G, Reals R, Janosik D, Labovitz A, Kennedy H (1987). Hemodynamic effects of rate responsive pacing in patients with left ventricular dysfunction measured by 2d and Doppler echocardiography. PACE 10 (PartII):652Google Scholar
  55. Buetikofer J, Milstein S, Mianulli M, Benditt DG (1987). Sustained improvement in peak oxygen consumption with activity-initiated rate-variable pacing. PACE 10(PartII):652Google Scholar
  56. Callaghan F, Camerlo J, Tarjan P (1987). The ventricular depolarization gradient: Exercise performance of a closed-loop rate responsive pacemaker. PACE 10:1212Google Scholar
  57. Camilo V, Correia-Cunha J, Rosario E, Fernandes F, Vagueira C, Amram S (1987). Pacemaker syndrome. Alternative therapeutic options. PACE 10 (PartII):655Google Scholar
  58. Camm AJ, Garratt CJ (1988). Rate-adaptive pacing guided by minute ventilation. In: Santini M, Pistolese M, Alliegro A (eds). Progress in clinical pacing. Excerpta Medica, Amsterdam, Hong Kong, Manila, Princeton, Sydney, Tokyo, p107Google Scholar
  59. Cammilli L, Alcidi L, Papeschi G (1977). A new pacemaker autoregulating the rate of pacing in relation to metabolic needs. In: Watanabe Y (ed) Cardiac pacing. Excerpta Medica, Amsterdam, p414Google Scholar
  60. Carleton RA, Passovoy M, Graetinger JS (1966). The importance of the contribution and timing of left atrial systole. Clin Sci 30:151PubMedGoogle Scholar
  61. Castellanet M, Famuralo M, Messenger J, Ellestad MH (1981). Atrial pacing — 10 year experience. Chest 80:346Google Scholar
  62. Castillo C, Samet P (1967). Retrograde conduction in complete heart block. Br Heart J 29:553PubMedCrossRefGoogle Scholar
  63. Chamberlain DA, Leinbach RC, Vassaux CE, Kastor JA, DeSanctis RW, Sanders CE (1970). Sequential atrioventricular pacing in heart block complicating acute myocardial infarction. N Engl J Med 282:577PubMedCrossRefGoogle Scholar
  64. Chan W, Kertes P, Mond H, Hunt D (1983). The effects of altering heart rate on supine cardiac volumes at rest during ventricular inhibited pacing. PACE 6: A-79Google Scholar
  65. Chirife R (1987). The pre-ejection period: an ideal physiologic variable for closed-loop rate responsive pacing. PACE 10(76):425Google Scholar
  66. Citron P, Smyth NPD, Kleinert M, Kahn AR (1978). Clinical experiences with a new transvenous atrial lead. Chest 73:193PubMedCrossRefGoogle Scholar
  67. Cohen TJ (1984). A theoretical right atrial pressure feedback heart rate control system to restore physiological control to the rate-limited heart. PACE 7:671PubMedCrossRefGoogle Scholar
  68. Cohen TJ, Venltri EP, Lattuca J, Mower MM (1988). Hemodynamic responses to rapid pacing. A model for tachycardia differentiation. PACE 11:1522Google Scholar
  69. Conde CA, Leppo J, Lipski J, Stimmel B, Litwak R, Donoso E, Dack S (1973). Effectiveness of pacemaker treatment in the bradycardia-tachycardia syndrome. Am J Cardiol 32:209PubMedCrossRefGoogle Scholar
  70. Contini C, Pauletti M, Moscarelli E, Levorato D, Baratto M, Bongiorni G, Mazzocca G (1983). Evaluation of myocardial function in pacemaker (PM) patients (PTS) by means of a non-invasive doppler technique. PACE 6:A-87Google Scholar
  71. Contini C, Bongiorni MG, Arlotta C, Paperini L, Levorato D, Baratto M, Piacenti M, Pozzolini A, Berti S (1988). Sinus node response to exercise in sick sinus syndrome patients. In: Santini M, Pistolese M, Alliegro A (eds). Progress in clinical pacing. Excerpta Medica, Amsterdam, Hong Kong, Manila, Princeton, Sydney, Tokyo, p9Google Scholar
  72. Costa R, Moreira LF, Rati M, Neto A, Stolf NA, Jatene AD (1985). Hemodynamic effects of atrial synchronous ventricular inhibited pacing in patients with Chagas cardiomyopathy. In: Gomez FP (ed) Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p513Google Scholar
  73. Costa R, Moreira LF, Martinelli F, Rati M, Stolf NAG, Verginelli G, Jatene AD (1988). Atrial synchronous pacing: a real benefit in cardiomyopathy? PACE 11 (Suppl) 816Google Scholar
  74. Creplet J, Sartieaux A, Bohyn P, Achkar F, Sacre J, Adda JL, Azancot I, De Mey D (1983). Study of the left ventricular performance during sequential and ventricular pacing by quantitative two dimensional echocardiography. PACE 6:A-76Google Scholar
  75. Crick JPC, Way B, Sowton E (1984). Successful treatment of ventricular tachycardia by physiological pacing. PACE 7:949PubMedCrossRefGoogle Scholar
  76. Curtis JJ, Madigan NP, Withing RB, Mueller KJ, Pezzella AT, Walls JT, Heinemann FM (1981). Clinical experience with permanent atrioventricular sequential pacing. Ann Thorac Surg, 32:179PubMedCrossRefGoogle Scholar
  77. Curtis J, Walls J, Boley T, Madigan N, Flaker G, Reid J (1983). Importance of atrio-ventricular contraction intervcal on hemodynamics. PACE 6: A-83Google Scholar
  78. Curzi GF, Massacci C, Viola C, Molini E, Constantini C, Giunti M, Berettini U, Purcaro A (1985). Actuarial survival curves and causes of death in patients treated with permanent VVI pacing. In: Gomez F P (ed) Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p1187Google Scholar
  79. Daggett WM, Bianco JH, Powell WJ, Austen WG (1970). Relative contributions of the atrial systole-ventricular systole interval and of pattern of ventricular activation to ventricular function during electrical pacing of the dog heart. Circ Res 27:69PubMedGoogle Scholar
  80. Daubert JC, Roussel A, Langella B, de Place C, Bourdonnec C, Gouffault J (1983). Hemodynamic and echocardiographic consequences of ventriculo-atrial conduction (VAC) in man. PACE 6:A-78Google Scholar
  81. Davidson DM, Braak CA, Preston TA, Judge RD (1972). Permanent ventricular pacing. Effect on long-term survival, congestive heart failure, and subsequent myocardial infarction and stroke. Ann Intern Med, 77:345Google Scholar
  82. Den Dulk K, Bouwels L, Lindemans F, Rankin I, Brugada P, Wellens HJJ (1988). The Activitrax rate responsive pacemaker system. Am J Cardiol 61:107CrossRefGoogle Scholar
  83. Dhingra RC, Palileo E, Strasberg B, Swiryn S, Bauernfeind RA, Wyndham CR, Rosen KM (1981). Significance of the HV interval in 517 patients with chronic bifascicular block. Circulation 64:1265PubMedCrossRefGoogle Scholar
  84. DiCarlo LA, Morady F, Krol R, Baerman JM, de Buitleir M, Schork A, Sereika S (1987). Role of the atrium during ventricular pacing: hemodynamic consequences of atrioventricular and ventriculoatrial pacing in humans. PACE 10(128):438Google Scholar
  85. DiCola VC, Stewart WJ, Harthorne JW, Weyman AE(1983). Doppler ultrasound measurement of cardiac output in patients with physiologic dual chamber pacemakers. PACE 6: A-86Google Scholar
  86. Djordjevic M, Stojanov P, Kocovic D, Jelic V, Velimirovic D (1987). Comparative effects of rate responsive activity pacing and VVI pacing on exercise capacity. In: Beihassen B, Feldmann S, Copperman Y. (eds). Cardiac pacing and electrophysiology. R&L Creative Communications Ltd, Jerusalem, p47Google Scholar
  87. Dolder A, Halter J, Nager F (1975). Schrittmacherimplantation bei bradykarder Herzinsuffizienz. Dtsch Med Wschr 100:2070PubMedCrossRefGoogle Scholar
  88. Donaldson RM, Richards AF (1983). Towards multisensor pacing. Am Heart J 106:1454PubMedCrossRefGoogle Scholar
  89. Dreifus LS, Naito M, David D Michelson EL (1983). Hemodynamic consequences of abnormal atrio-ventricular sequencing. PACE 6:81CrossRefGoogle Scholar
  90. Dreifus LS, Mitamura H, Rhauda A, Vail S, Michelson EL, Berkovits BV, Peterson DD, Figueroa WF (1986). Effects of AV sequential versus asynchronous AV pacing on pulmonary hemodynamics. PACE 9:171PubMedCrossRefGoogle Scholar
  91. Duval AM, Lellouche D, Dubois-Rande JL, Brun P, Vernant P, Castaigne A (1988). Relationship between A.V. delay and left ventricular filling in VDD mode pacing. PACE 11 (Suppl): 817Google Scholar
  92. Edhag O, Swahn A (1976). Prognosis of patients with complete heart block or arrhythmic syncope who were not treated with artificial pacemakers. Acta Med Scand 200:457PubMedCrossRefGoogle Scholar
  93. Eimer HH, Witte J (1974). Zur Leistungsbreite bei Patienten mit festfrequentem Herzschrittmacher unter Berücksichtigung von Hämodynamik, arteriovenöser Sauerstoffdifferenz und Lungenfunktion. Z Kar-diol 1099:63Google Scholar
  94. Eisinger GE, Winston SA, McGaughey MD (1988). Rate responsive AV delay and its effect on upper rate limit performance in DDD pacemakers. PACE 11 (Suppl): 815Google Scholar
  95. Elmquist R, Senning A (1959). An implantable pacemaker for the heart. In: Smyth CN (ed) Medical electronics, proceedings of the second international conference on medical electronics. Iliffe & Sons, London, p253Google Scholar
  96. Errazquin F, Vazquez R, Nieto J, Gascon D (1985). Ventriculo atrial conduction. In: Gomez FP (ed) Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p719Google Scholar
  97. Estioko M, Camunas J, Halperin J, Rothlauf E, Steinmetz M, Teichholz L (1983). Pulsed-doppler echocardiographic assessment of hemodynamic function during dual-chamber cardiac pacing. PACE 6:A-87Google Scholar
  98. Evans R, Shaw DB (1977). Pathological studies in sinoatrial disorder (sick sinus syndrome). Brit Heart J 39:778PubMedCrossRefGoogle Scholar
  99. Faerestrand S, Ohm OJ (1985). A time related study of the hemodynamic benefit of atrioventricular synchronous pacing evaluated by Doppler echocardiography. PACE 8:838PubMedCrossRefGoogle Scholar
  100. Faerestrand S, Ohm OJ (1987). Activity-sensing rate-responsive ventricular pacing (VVI): relation between left ventricular dimensions and improvement in work capacity. PACE 10:1211Google Scholar
  101. Fairfax AJ, Lambert CD, Leatham A (1976). Systemic embolism in chronic sinoatrial disorder. N Engl J Med 295:190PubMedCrossRefGoogle Scholar
  102. Fananapazir L, Srinivas V, Bennett DH (1983a). Comparison of resting hemodynamic indices and exercise performance during atrial synchronized and asynchronous pacing. PACE 6:202PubMedCrossRefGoogle Scholar
  103. Fananapazir L, Bennett DH, Monks P (1983b). Atrial synchronized pacing: contribution of the chronotropic response to improved exercise performance. PACE, 6:601PubMedCrossRefGoogle Scholar
  104. Fearnot NE, Smith HJ (1986). Trends in pacemakers which physiologically increase rate: DDD and rate responsive. PACE 9(PartII): 939PubMedCrossRefGoogle Scholar
  105. Ferrer I (1968). The sick sinus syndrome in atrial disease. JAMA 206:645PubMedCrossRefGoogle Scholar
  106. Feruglio GA, Rickards AF, Steinbach K, Feldman S, Parsonnet V (1987). Cardiac pacing in the world: A survey of the state of the art in 1986. PACE 10 (PartII): 768Google Scholar
  107. Fetter J, Mianulli M, Benditt DG (1987). Transcutaneous triggering of conventional implanted pulsegenerators: a technique for predicting benefits of activity initiated rate-variable pacing. PACE 10:432Google Scholar
  108. Fields J, Berkovits BV, Matloff JM (1973). Surgical experience with temporary and permanent A-V sequential pacing. J Thorac Cardiovasc Surg 66:865PubMedGoogle Scholar
  109. Folkman MJ Watkins E (1957). An artificial conduction system for the management of experimental complete heart block. Surg. For. 8:331Google Scholar
  110. Forfong K, Otterstad JE, Ihlen H (1986). Optimal atrioventricular delay in physiological pacing determined by Doppler echocardiography. PACE 9:17CrossRefGoogle Scholar
  111. Frank O (1895). Zur Dynamik des Herzmuskels. Z Biol 32:371Google Scholar
  112. Frank O (1901). Isometrie und Isotonie des Herzmuskels. Z.Biol 41:14Google Scholar
  113. French WJ, Florio JJ (1988). Mode change during DDD/rate responsive pacing: technical benefits and physiologic results. PACE 11 (Suppl):798CrossRefGoogle Scholar
  114. Friedberg CK, Donoso K, Stein WG (1964). Nonsurgical acquired heart block. Ann NY Acad Sci 111:835PubMedCrossRefGoogle Scholar
  115. Fujiyama M, Furuta Y, Matsumura J, Tanabe A, Ikeda H, Toshima H (1983). Reconsideration of heart rate (HR)-cardiac output (COP) curve and resting cardiac function in bradyarrhythmias. PACE 6:A-83Google Scholar
  116. Funke HD (1975). Ein Herzschrittmacher mit belastungsabhängiger Frequenzregulation. Biomed Technik 20:225CrossRefGoogle Scholar
  117. Funke HD, Helpers L (1978). Electrocardiographic findings in patients treated with optimized sequential stimulation. 1st Europ Symp. on Cardiac Pacing,7.5.-9.5.pp 43Google Scholar
  118. Furman S, Robinson G (1958). The use of an intracardiac pacemaker in the correction of total heart block. Surg Forum 9:245PubMedGoogle Scholar
  119. Furman S (1973). Therapeutic uses of atrial pacing. Am Heart J 86:835PubMedCrossRefGoogle Scholar
  120. Furman S (1988). Sensors for rate modulated pacing. PACE 11:1249PubMedCrossRefGoogle Scholar
  121. Gamal MIH, van Gelder LM (1981). Chronic ventricular pacing with ventriculo-atrial conduction versus atrial pacing in three patients with symptomatic sinus bradycardia. PACE 4:100PubMedCrossRefGoogle Scholar
  122. Gann D, Tolentino A, Samet P (1979). Electrophysiologic evaluation of elderly patients with sinus bradycardia. Ann Int Med 90:24PubMedGoogle Scholar
  123. Gattenlöhner W, Schneider KW (1973). Schrittmachertherapie und Hämodynamik. Münch Med Wschr 115:2137PubMedGoogle Scholar
  124. Gerhard W, Smekal P, Grosser KD (1976). Kreislaufdynamik bei totalem atrioventrikulären Block vor und nach Anwendung eines elektrischen Schrittmachers unter verschiedenen Frequenzen. Dtsch Med Wschr 34:1488Google Scholar
  125. Gershony G, Noble EJ, Goldman BS, Pollick C (1983). Mitral valve function and cardiac dimensions during ventricular (VVI) and sequential atrioventricular (DVI) pacing. Echocardiographic study. PACE 6:A-75Google Scholar
  126. Gesell RA (1916). Cardiodynamics in heart block as affected by auricular systole, auricular fibrillation and stimulation of the vagus nerve. Am J Physiol 40:267Google Scholar
  127. Gillespie WI, Greene DG, Karatzas NB, Lee GJ (1967). Effect of atrial systole on right ventricular stroke output in complete heart block. Brit Med J 1:75PubMedCrossRefGoogle Scholar
  128. Gillette PC (1984). Critical analysis of sensors for physiological responsive pacing. PACE 7 (Part II):1263PubMedCrossRefGoogle Scholar
  129. Gillette PC, Wampler DG, Shannon C, Ott D (1985). Use of atrial pacing in a young population. PACE 8:94PubMedCrossRefGoogle Scholar
  130. Gilmore J, Sarnoff SJ, Mitchell JH, Linden RJ (1963). Synchronicity of ventricular contraction: observations comparing hemodynamic effects of atrial and ventricular pacing. Br Heart J 25:299PubMedCrossRefGoogle Scholar
  131. Goicoleade Oro, Ayza W, Liana L, Morales JA, Diez JRG, Alvarez JG (1985). Rate-responsive pacing: clinical experience. PACE 8 (Part I):322CrossRefGoogle Scholar
  132. Goldman BS, Williams WG, Hill T, Hesslein PS, McLaulin PR, Trusler GA, Baird RJ (1985). Permanent cardiac pacing after open heart surgery: congenital heart disease. PACE 8:732PubMedCrossRefGoogle Scholar
  133. Goldreyer BN, Bigger J (1970). Ventriculo-atrial conduction in man. Circulation 61:935Google Scholar
  134. Goldreyer BN (1982). Physiological pacing: The role of AV synchrony. PACE 5:613PubMedCrossRefGoogle Scholar
  135. Grant C, Bunnell IL, Greene DG (1964). The reservoir function of the left atrium during ventricular systole. An angiocardiographic study of atrial stroke volume and work. Am J Med 37:36Google Scholar
  136. Greco OT, Ardito RV, Bellini AJ, Brambatti JC, Fedozzi, NM, Silveira LC, Lorga A, Braile DM (1987). Rate responsive pacing in Chagas heart disease. PACE 10:1213Google Scholar
  137. Greenberg P, Castellanet M, Messenger J, Ellestad MH (1978). Coronary sinus pacing. Clinical follow-up. Circulation 57:98Google Scholar
  138. Greenberg B, Chatterjee K, Parmley WW, Werner JA, Holly AN (1979). The influence of left ventricular filling pressure on atrial contribution to cardiac output. Am Heart J 98:742PubMedCrossRefGoogle Scholar
  139. Griebenow R, Saborowski F, Hessman V, Meier J (1985). Langzeitergebnisse der permanten Vorhofschrittmachertherapie. Herzschrittmacher 5:38Google Scholar
  140. Guyton RA, Andrews MJ, Hickey PR, Michaelis LL, Morrow AG (1976). The contribution of atrial contraction to right heart function before and after right ventriculotomy. J Thorac Cardiovasc Surg 71:1PubMedGoogle Scholar
  141. Haas JM, Strait, GB (1974). Pacemaker-induced cardiovascular failure. Hemodynamic and angiographic observations. Am J Cardiol 33:295Google Scholar
  142. Hamby RI, Aintablian A, Wisoff BG (1973). The role of atrial systole in valve closure. Chest 64:197PubMedCrossRefGoogle Scholar
  143. Hanson JF, Meibom J (1974). The prognosis for patients with complete heart block treated with permanent pacemaker. Acta Med Scand 195:385CrossRefGoogle Scholar
  144. Härtel G, Talvensaari T (1975). Treatment of sinoatrial syndrome with permanent cardiac pacing in 90 patients. Acta med Scand 198:341PubMedCrossRefGoogle Scholar
  145. Hartmann S, Konz KH, Völker W, Haasis R (1987). Improved exercise performance with an activity sensing pacemaker following augmented muscle p02 distribution. PACE 10 (PartII):685Google Scholar
  146. Hartzler GO, Maloney JD, Curtis JJ, Earnhorst DA (1977). Hemodynamic benefits of atrioventricular sequential pacing after cardiac surgery. Am J Cardiol 40:232PubMedCrossRefGoogle Scholar
  147. Haskell RJ, French WJ (1986). Optimum AV interval in dual chamber pacemakers. PACE 9:670PubMedCrossRefGoogle Scholar
  148. Häuser RG, Jones J, Edwards LM, Messer JV (1983). Prognosis of patients paced for AV block or sinoatrial disease in the absence of ventricular tachycardia. PACE 6:A123Google Scholar
  149. Hauser RG (1984). Techniques for improving cardiac performance with implantable devices. PACE 7 (PartII):1234PubMedCrossRefGoogle Scholar
  150. Hayes DL, Vlietstra RE, McGoon MD, Brown ML, Holmes DR, Gersh BJ (1983). Comparison of exercise responses during ventricular and physiologic pacing. PACE 6: A-81CrossRefGoogle Scholar
  151. Hayes DL, Furman S (1984). Stability of AV-conduction in sick sinus syndrome patients with implanted atrial pacemakers. Am Heart J 107:644PubMedCrossRefGoogle Scholar
  152. Hedman A, Nordlander R (1988). QT sensing rate responsive pacing versus fixed rate ventricular pacing — a controlled clinical study. PACE 11:506CrossRefGoogle Scholar
  153. Hetzel MR, Ginks WR, Pickersgill AJ, Leatham A (1978). Value of pacing in cardiac failure associated with chronic atrioventricular block. Br Heart J 40:864PubMedCrossRefGoogle Scholar
  154. Heuer H, Koch T, Frenking B, Bender F (1986). Erste Erfahrungen mit einem zweisensorgesteuerten freuqenzadaptierten System. Z Kardiol 75 (Suppl): 78Google Scholar
  155. Heuer H, Koch T, Isbruch F, Gülker H (1987). Pacemaker stimulation by a two sensor regulation. PACE 10(Part II):688Google Scholar
  156. Humen DP, Anderson K, Brumwell D (1983). A pacemaker which automatically increases its pacing rate with physical activity. In: Steinbach K. (ed) Cardiac pacing. Proceedings of the VIIIth World Symp. Steinkopff Darmstadt, p259Google Scholar
  157. Humen DP, Kostuk WJ, Klein GJ (1985). Activity-sensing, rate-responsive pacing: improvement in myocardial performance with exercise. PACE 8:52PubMedCrossRefGoogle Scholar
  158. Humphries JO, Hinman EJ, Bernstein L, Walker WG (1967). Effect of artificial pacing on cardiac and renal function. Circulation 36:717PubMedGoogle Scholar
  159. Huxley H, Hanson J (1954). Changes in in the cross-striations of muscle during contraction and stretch and their structural interpretation. Nature (London) 173:973CrossRefGoogle Scholar
  160. Hyman AS (1930).Resuscitation of the stopped heart by intracardiac therapy. Arch Intern Med 46:553Google Scholar
  161. Hyman AS (1932). Resuscitation of the stopped heart by intracardiac therapy. Experimental use of an artificial pacemaker. Arch Intern Med 50:283Google Scholar
  162. Ikkos D, Hanson JS (1960). Response to exercise in congenital complete atrioventricular block. Circulation 12:583Google Scholar
  163. Irnich W, Bleifeld W, Effert S (1972). Permanente transvenöse Elektrostimulation des Herzens mit einer myokardial fixierten Elektrode. Thoraxchir 20:440Google Scholar
  164. Irnich W, Conrady J (1987). A new principle of rate adaptive pacing in patients with sick sinus syndrome. PACE 10 (Part II):692Google Scholar
  165. Isbruch FM, Koch T, Frenking B, Chiladakis I, Greve H, Gülker H, Heuer H (1988). Long term study of retrograde conduction in patients with permanent pacing systems. PACE 11:842Google Scholar
  166. Janosik D, Pearson A, Redd R, Blum R, Buckingham T, Mrosek D, Labovitz A (1987). The importance of atrioventricular delay fallback in optimizing cardiac output during physiologic pacing. PACE 10:410Google Scholar
  167. Jochim K (1938). The contribution of the auricles to ventricular filling in complete heart block. Am J Physiol 122: 639Google Scholar
  168. Johansson BW (1969). Longevity in complete heart block. Ann NY Acad Sci 167:1031PubMedCrossRefGoogle Scholar
  169. Johnson AD, Laiken SL, Engler RL (1978). Hemodynamic compromise associated with ventriculo-atrial conduction following transvenous pacemaker placement. Am J Med 65:75PubMedCrossRefGoogle Scholar
  170. Joseph SP, White J (1979). Long-term atrial pacing for sinus node disease with output-terminal programmable pacemakers. J Thorac Cardiovasc Surg 78: 292PubMedGoogle Scholar
  171. Kahn M, Senderoff E, Shapiro J, Bleifer, SB, Grishman A (1970). Bridging of interrupted A-V conduction in experimental chronic complete heart block by electronic means. Am Heart J 59:548CrossRefGoogle Scholar
  172. Kappenberger L, Gloor HO, Babotai I, Steinbrunn W, Turina M (1082). Hemodynamic effects of atrial synchronization in acute and long-term ventricular pacing. PACE 5:639Google Scholar
  173. Kappenberger L, Goy JJ, Sigwart U, Michel B (1986). Rate-responsive dual chamber pacing. PACE 10(PartII):694Google Scholar
  174. Kappenberger L (1988). Dual chamber rate responsive pacing. In: Santini M, Pistolese M, Alliegro A (eds). Progress in clinical pacing. Excerpta Medica, Amsterdam, Hong Kong, Manila, Princeton, Sydney, Tokyo, p135Google Scholar
  175. Karlöf I (1975). Haemodynamic effect of atrial triggered versus fixed rate pacing at rest and during exercise in complete heart block. Acta Med Scand 197:195PubMedGoogle Scholar
  176. Kastor JA, DeSanctis RW, Leinbach RC, Harthorne JW, Wolfson IN (1969). Long-term pervenous atrial pacing. Circulation XII:535Google Scholar
  177. Kato R, Terasawa T, Gotoh T, Suzuki M (1988). Antiarrhythmic efficacy of atrial demand (AAI) and rate responsive pacing. In: Santini M, Pistolese M, Alliegro A (eds). Progress in clinical pacing. Excerpta Medica, Amsterdam, Hong Kong, Manila, Princeton, Sydney, Tokyo, p15Google Scholar
  178. Katz AM (1970). Contractile proteins of the heart. Physiol Rev 50:63PubMedGoogle Scholar
  179. Kay GN, Bubien R (1988). Effect of His bundle ablation and rate responsive pacing on exercise capacity and qualitiy of life in patients with atrial fibrillation. PACE 11:500CrossRefGoogle Scholar
  180. Kleinert MP, Bisping HJ (1977). Erste klinische Erfahrungen mit einer neuen transvenös endokardialen Schraubelektrode in Vorhof-und Kammerposition. Z Kardiol 66:454PubMedGoogle Scholar
  181. Kleinert MP, Beckedorf H (1983). Incidence of conduction disturbances in permanent atrial pacing. J Am Coll Cardiol 1(2):720Google Scholar
  182. Knapp K, Gmeiner R, Hammerle P, Raas E (1976) Der Einfluß der Vorhofkontraktion auf das Schlagvolumen bei Schrittmacherstimulation. Z Kardiol 65:783PubMedGoogle Scholar
  183. Koretsune Y, Kodama K, Nanto S, Ishikawa K, Taniura K, Mishima M, Inoue M, Abe H (1983). The effect of pacing mode on external work and myocardial oxygen consumption. PACE 6:A-77Google Scholar
  184. Kourkoulados C, Gialafos J, Paraskevas P, Tsakiris M, Kremastinos D, Toutouzas P (1985). Assessment of left ventricular function in ventricular and A-V pacing using systolic time intervals and thermodilution technique. In: Gomez FP (ed). Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p610Google Scholar
  185. Krishnaswami V, Geraci AR (1975). Permanent pacing in disorders of sinus node function. Am Heart J 89:579PubMedCrossRefGoogle Scholar
  186. Kristensson BE, Amman K, Ryden L (1983). Atrial synchronous ventricular pacing in ischemic heart disease. Eur Heart J 4:668PubMedGoogle Scholar
  187. Kristensson BE, Amman K, Ryden L (1985). The hemodynamic importance of atrioventricular synchrony and rate increase at rest and during exercise. Eur Heart J 6:773PubMedGoogle Scholar
  188. Kristensson BE, Amman K, Ryden L (1986). The relative importance of AV-synchrony and rate increase for exercise hemodynamics in patients with and without myocardial disease. PACE 9(65):291Google Scholar
  189. Kruse IM, Amman K, Conradson TB, Ryden L (1982). A comparison of the acute and long-term hemodynamic effects of ventricular inhibited and atrial synchronous ventricular inhibited pacing. Circulation 65:846PubMedCrossRefGoogle Scholar
  190. Kruse IM (1988). Long-term improvements in functional capacity by AAI-rate responsive pacing. In: Santini M, Pistolese M, Alliegro A (eds) Progress in clinical pacing. Excerpta Medica, Amsterdam, Hong Kong, Manila, Princeton, Sydney, Tokyo, p25Google Scholar
  191. Ladusans E, Priestley K, Rosenthal E, Tynan M, Curry PVL (1987). Rate responsive pacing improves effort capacity compared with VVI pacing in children with symptomatic bradycardia. PACE 10:1216Google Scholar
  192. Lagergren H, Johansson L, Schüller H, Kugelberg J, Bojs G, Alestig K, Linder E, Borst HG, Schaudig A, Giebel O, Harms H, Rodewald G, Scheppokat KD (1966). 305 cases of permanent intravenous pacemaker treatment for Adams-Stokes syndrome. Surgery 59:494PubMedGoogle Scholar
  193. Lascault G, Bigonzi F, Lechat P, Eugene M, Frank R, Fontaine G, Grosgogeat H (1988). Efficacy of DDD pacing in dilated cardiomyopathy: assessment by pulsed Doppler echocardiography. Preliminary results. PACE 11(Suppl): 851Google Scholar
  194. Laczkovics A, Mohl W, Steinbach K (1979). Life expectance of patients (pts.) dependent on age and indication for PM treatment. In: Meere C (ed) Proceedings of the VIth World Symposium on Cardiac Pacing,Chap. 13-4Google Scholar
  195. Langenfeld H, Grimm W, Maisch B, Kochsiek K (1988). Course of symptoms and spontaneous ECG in pacemaker patients: a 5-year follow-up study. PACE 11:2198PubMedCrossRefGoogle Scholar
  196. Lau C, Tse W, Camm AJ (1988a). Clinical experience with Sensolog 703: a new activity sensing rate responsive pacemaker. PACE 11:1444Google Scholar
  197. Lau C, Drysdale M, Ward D, Camm J (1988b). Clinical experience of Meta: a minute ventilation sensing rate responsive pacemaker. PACE 11:507Google Scholar
  198. Laule M, Stangl K, Wirtzfeld A (1988). Adaptation to exercise: role of cardiac output, stroke volume and mixed venous oxygen saturation under atrial triggered vs fixed rate ventricular pacing. PACE 11(Suppl): 814Google Scholar
  199. Lemke B, Hoeltmann BJ, Selbach H, Barmeyer J (1987). Der Vorhofschrittmacher als Therapie der Sinusknotenerkrankung: Retrospektive Analyse der Komplikationen und Überlebensraten. Z Kardiol 76:479Google Scholar
  200. Levander-Lingren M, Lantz B (1988). Bradyarrhthmia profile and associated diseases in 1,265 patients with cardiac pacing. PACE 11:2207CrossRefGoogle Scholar
  201. Lindemans FW, Rankin IA, Murtaugh R, Chevalier PA (1986). Clinical experience with an activity sensing pacemaker. PACE 9 (PartII):978PubMedCrossRefGoogle Scholar
  202. Linderer T, Leitner ER, Biamino G, Schröder R (1983). Effects of atrial contribution to ventricular filling: The quantitative increase in cardiac output due to AV sequential pacing. PACE 6:A-77Google Scholar
  203. Lipkin DP, Buller N, Frenneaux M, Ludgate L, Lowe T, Webb SC, Krikler DM (1987). Randomized crossover trial of rate responsive Activitrax and conventional rate ventricular pacing. Br Heart J 58:613PubMedCrossRefGoogle Scholar
  204. Little RC (1951). Effect of atrial systole on ventricular pressure and closure of the A-V valves. Am J Physiol 166:289PubMedGoogle Scholar
  205. Liu P, Burns RL, Weisel RD, Mickleborough L, McLaughlin PR (1983). Comprehensive evaluation of left ventricular function during physiological pacing. PACE 6:A-77Google Scholar
  206. Lown B (1967). Electrical reversion of cardiac arrhythmias. Brit Heart J 29:469PubMedCrossRefGoogle Scholar
  207. Lüderitz B (1979). Elektrische Stimulation des Herzens. Springer, Berlin, Heidelberg, New YorkCrossRefGoogle Scholar
  208. Lüderitz B (1987). Bradykarde Rhythmusstörungen. In: Lüderitz B.(Hrsg) Therapie der Herzrhythmustörungen. Leitfaden für Klinik und Praxis. Springer, Berlin, Heidelberg, New York, London, Paris, Tokyo, S185Google Scholar
  209. Maisch B (1988). Vor-und Nachteile der Vorhofstimulation bei Sinusknotensyndrom. Herzschrittmacher 8:109Google Scholar
  210. Mandel WJ, Kermaier AI, Blum RL, Hayakawa H (1972). Critical prolongation of AV conduction time as the inciting mechanism in reentrant tachycardia. J Electrocardiol 5:39PubMedCrossRefGoogle Scholar
  211. Manz M, Pfitzner P, Lüderitz B (1987). Rate responsive pacing after his bundle ablation and for sick sinus syndrome. PACE 10:1219Google Scholar
  212. Maring EG, Roell AM, Luttikhuis H (1987). Ambulatory monitoring in sick sinus syndrome after implantation of atrial pacemakers. PACE 10 (Part II):711Google Scholar
  213. Markewitz A, Schad N, Hemmer W, Bernheim C, Ciavolella M, Weinhold C (1986). What is the most appropriate stimulation mode in patients with sinus node dysfunction? PACE 9 (Part II): 1115PubMedCrossRefGoogle Scholar
  214. Mast EG, Hebel NW, Bakema L, Derksen B, Defauw JAM (1986). Is chronic atrial stimulation a reliable method for single chamber pacing in sick sinus syndrome? PACE 9 (Part II): 1127PubMedCrossRefGoogle Scholar
  215. Matloff JM, Berkovits BV Fields JJ (1970). Experience with implanted bifocal, sequential demand pacing. Circulation (Suppl.III) 42:182Google Scholar
  216. Maurer G, Torres M, Haendchen RV, Meerbaum S, Corday E (1983). Pacing-induced mitral regurgitation: Contrast echocardiographic and hemodynamic evaluation. PACE 6: A-75Google Scholar
  217. McAnulty JH, Rahimtoola SH, Murphy E, De Mots H, Ritzmann L, Kanarek PP, Kauffman S (1982). Natural history of „high-risk“ bundle branch block. N Engl J Med 307:137PubMedCrossRefGoogle Scholar
  218. McGregor M, Klassen GA (1964). Observations on the effect of heart rate and cardiac output in patients with complete heart block at rest and during exercise. Circ Res 11:215Google Scholar
  219. McKay RG, Spears JR, Aroesty JM, Bairn DS, Royal HD, Heller GV, Lincoln W, Salo RW, Braunwald E, Grossman W (1984). Instantaneous measurement of left and right ventricular stroke volume and pressure-volume relationship with an impedance catheter. Circulation 69:703PubMedCrossRefGoogle Scholar
  220. Mehta D, Gilmour S, Lau C, Davies W, Camm J (1987). Optimal atrioventricular interval in patients with dual chamber pacemakers. PACE 10:437Google Scholar
  221. Mitchell JH, Gilmore JP, Sarnoff SJ (1962). The transport function of the atrium. Am J Cardiol. p. 237Google Scholar
  222. Mitchell JH, Gupta DN, Payne RM (1965). Influence of atrial systole on effective ventricular stroke volume. Circ Res 17:11PubMedGoogle Scholar
  223. Mitrovics V, Neuss H, Buss J, Thormann J, Schlepper M (1982). Hämodynamische Folgen beim Wegfall der Vorhofkontraktion. Z Kardiol 71:824Google Scholar
  224. Mitsuoka T, Kenny RA, Yeung TA, Chan SL, Perrins JE, Sutton R (1988). Benefits of dual chamber pacing in sick sinus syndrome. Br Heart J 60:338PubMedCrossRefGoogle Scholar
  225. Moreira LFP, Costa R, Fernandes PMP, (1985). Reevaluation of the role of atrial systole in the closure of atrioventricular valves. In: Gomez FP (ed) Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p554Google Scholar
  226. Moss AJ, Rivers RJ (1978). Atrial pacing from the coronary vein. Circulation 57:103PubMedGoogle Scholar
  227. Müller OF, Bellet S (1961). Treatment of intractable heart failure in the presence of complete atrioventricular heart block by the use of the internal cardiac pacemaker. New Engl J Med 265:769CrossRefGoogle Scholar
  228. Müller C, Cernin J, Glogar D, Laczkovics A, Mayr H, Scheibelhofer W, Schmidinger H, Schuster E, Sedlacek K, Kaliman J (1988). Survival rate and causes of death in patients with pacemakers: dependence on symptoms leading to pacemaker implantation. Europ Heart J 9:1003Google Scholar
  229. Munteanu J, Wirtzfeld A, Stangl K, Alt E, Seidl F (1985). Is the hemodynamic benefit of VDD pacing due to AV-synchrony or to rate responsiveness? In: Gomez FP (ed) Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p893Google Scholar
  230. Nager F, Bühlmann A, Schaub F (1966). Klinische und hämodynamische Befunde beim totalen AV-Block nach Implantation elektrischer Schrittmacher. Helv Med Acta 33:240PubMedGoogle Scholar
  231. Naito M, Dreifus LS, Mardelli TJ, Chen CC, David D, Michelson EL, Marcy V, Morganroth J (1980). Echocardiographic features of atrioventricular and ventriculo-atrial conduction. Am J Cardiol 46:625PubMedCrossRefGoogle Scholar
  232. Naito M, David D, Michelson EL, Morganroth J, Dreifuß LS (1980). Pulmonary venous regurgitation: a major factor adversely affecting hemodynamics ventriculo-atrial pacing. Pace 3:381Google Scholar
  233. Narahara KA, Blettel ML (1983). Effect of rate on left ventricular volumes and ejection fraction during chronic ventricular pacing. Circulation 67(2):323PubMedCrossRefGoogle Scholar
  234. Narula OS, Gann D, Samet P (1975). Prognostic value of HV interval. In: Narula OS (ed) His bundle electro-cardiography and clinical electrophysiology. Davis Comp., Philadelphia, p437Google Scholar
  235. Nathan DA, Center S, Wu CY, Keller W (1963). An implantable synchronous pacemaker for the long term correction of complete heart block. Am J Cardiol 11:362PubMedCrossRefGoogle Scholar
  236. Neuss H, Schaumann HJ, Stegaru B (1976). Drug effects of AV conduction. In: Lüderitz B (ed) Cardiac pacing. Diagnostic and therapeutic tools. Springer, Berlin, Heidelberg, New York, p132Google Scholar
  237. Neuss H (1983). Bradykarde Rhythmusstörungen. In: Lüderitz B. (Hrsg) Herzrhythmusstörungen. Springer, Berlin, Heidelberg, New York, S549CrossRefGoogle Scholar
  238. Niederlag W, Rentsch W, Foelske H, Wunderlich E, Schmidt PKH (1987). Rate control of physiological pacemakers by systolic time intervals (STI). PACE 10:1222Google Scholar
  239. Nielsen ER, Simonsen EH, Nielsen G, Tonnesen J (1987). Maximum exercise capacity in three different pacing modes. A double blind study. PACE 10:1222Google Scholar
  240. Nishimura RA, Gersh BJ, Vlietstra RE, Osborn MJ, Ilstrup DM, Holmes DR (1982). Hemodynamic and symptomatic consequences of ventricular pacing. PACE 5:903PubMedCrossRefGoogle Scholar
  241. Nitsch J, Seiderer M, Büll U, Lüderitz B (1983). Auswirkungen unterschiedlicher Schrittmacherstimulation auf linksventrikuläre Volumendaten-Untersuchungen mit der Radionuklid-Ventrikulographie. Z Kardiol 72:718PubMedGoogle Scholar
  242. Nobile A, Montenero S, Scabbia E, Zecchi P, Bellocci F (1987). Long-term follow-up of activity sensing rate responsive pacemaker. PACE 10:1223Google Scholar
  243. Noll B, Krappe J, Goeke B (1988). Beeinflussung des atrialen natriuretischen Faktors durch die AV-Überleitungszeit bei Schrittmacherträgern. Dtsch Med Wschr 113:1994PubMedCrossRefGoogle Scholar
  244. Nordlander R, Pehrsson SK, Aström, H Karlsson J (1987). Myocardial demands of atrial triggered versus fixed rate ventricular pacing in patients with complete heart block. PACE 10:1154PubMedCrossRefGoogle Scholar
  245. Norman R, West RO, Burggraf GW (1986). Echocardiographic assessment of tricuspid regurgitation during ventricular demand pacing. PACE 9:290Google Scholar
  246. O’Connor Allen MJ, Arentzen CE, Anderson RW, Visner MS, Fetter J, Benditt DG (1988). Contribution of atrioventricular synchrony to left ventricular systolic function in a closed-chest canine model of complete heart block: implications for single-chamber rate-variable cardiac pacing. PACE 11:404CrossRefGoogle Scholar
  247. Ogawa S, Dreifus L, Shenoy PN, Brockman SK, Berkovits BV (1978). Hemodynamic consequences of atrioventricular and ventriculo-atrial pacing. PACE 1:8PubMedCrossRefGoogle Scholar
  248. Page E, Wolf JE, Billette A, Contamin C, Denis B (1988). The usefulness of a non invasive method to predict the benefits of rate responsive pacing in patients with complete atrioventricular block previously implanted in VVI mode. PACE 11 (Suppl):850CrossRefGoogle Scholar
  249. Papouchado M, Pitcher DW (1986). Ventricular pacing improves exercise tolerance in patients with chronic heart block. Br Heart J 56:366PubMedCrossRefGoogle Scholar
  250. Parsonnet V (1984). Indications for dual chamber pacing. PACE 7:318PubMedCrossRefGoogle Scholar
  251. Pasquier J, Adamec R, Velebit V, von Segesser L (1986). Amelioration a long terme des performances a l’effort des porteurs du stimulateur cardiaque a frequence asservie a l’activite physique. Schweiz Med Wschr 116:1604PubMedGoogle Scholar
  252. Patel AK, Yap VU, Thomsen JH (1977). Adverse effects of right ventricular pacing in a patient with aortic stenosis. Hemodynamic documentation and management. Chest 72:103Google Scholar
  253. Pehrsson SK, Aström H (1983). Left ventricular function after long-term treatment with ventricular inhibited compared to atrial triggered ventricular pacing. Acta Med Scand 214:295PubMedCrossRefGoogle Scholar
  254. Pehrsson SK (1983). Influence of heart rate and atrioventricular synchronization on maximal work tolerance in patients treated with artificial pacemakers. Acta Med Scand 214:311PubMedCrossRefGoogle Scholar
  255. Pehrsson SK, Hedman A, Hjemdahl P, Nordlander R, Aström H (1987). Myocardial oxygen uptake and sympathetic activity — a comparison between fixed rate ventricular pacing (VVI), atrial synchronous (VAT) and rate responsive QT sensing (TX) pacing. PACE 10:1224Google Scholar
  256. Penton GB, Miller H, Levine GA (1956). Some clinical features of complete heart block. Circulation 13:801PubMedGoogle Scholar
  257. Perrins EJ, Morley CA, Chan SL, Sutton R (1983). Randomized controlled trial of physiological and ventricular pacing. Br Heart J, 50:112PubMedCrossRefGoogle Scholar
  258. Peters RW, Scheinman MM, Dhingra R, Rosen K, McAnulty J, Rahimtoola SH, Modin G (1982). Serial electrophysiologic studies in patients with chronic bundle branch block. Circulation 65:1480PubMedCrossRefGoogle Scholar
  259. Petzold D, Haan D, Sill V (1970). Langzeitelektrokardiographie und Spiroergometrie bei Schrittmacher-Patienten. Wiederbelebung Organersatz Intensivmed 7:39Google Scholar
  260. Pipilis A, Bucknall C, Sowton E (1988). Sensolog — one year on. PACE 11 (Suppl):804Google Scholar
  261. Radford DJ, Julian DG (1974). Sick sinus syndrome: experience of a cardiac pacemaker clinic. Br Med J 3:504PubMedCrossRefGoogle Scholar
  262. Rasmussen K (1981). Chronic sinus node disease: natural course and indications for pacing. Eur Heart J 2:455PubMedGoogle Scholar
  263. Raza ST, Lajos TZ, Lewin AN, Lee AB, Bhayana JN, Gehring B, Puzio N, Schimert G (1983). Hemodynamic advantages of A-V sequential (DVI) pacing. Further enhancement by optimizing cardiac function. PACE 6: A-80Google Scholar
  264. Rediker DE, Eagle KA, Homma S, Gillam LD, Harthorne JW (1988). Clinical and hemodynamic comparison of VVI versus DDD pacing in patients with DDD pacemakers. Am J Cardiol 61:323PubMedCrossRefGoogle Scholar
  265. Reiter MJ, Hindman MC (1982). Hemodynamic effects of acute atrioventricular pacing in patients with left ventricular dysfunction. Am J Cardiol 49:687PubMedCrossRefGoogle Scholar
  266. Rettig G, Schieffer H, Doenecke P, Flöthner R, Drews H, Bette L (1975). Langzeitprognose bei Schrittmacherpatienten. Herz Kreisl 10:497Google Scholar
  267. Reynolds DW, Wilson MF, Burow RD, Schaefer CF, Lazzara R, Thadani U (1983). Hemodynamic evaluation of atrioventricular sequential versus ventricular pacing in patients with normal and poor ventricular function at variable heart rates and posture. PACE 6: A-80Google Scholar
  268. Richards AF (1985). Non atrial synchronous rate responsive pacing. In: Gomez FP (ed) Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p755Google Scholar
  269. Richards AM, Nicholls MG, Ikram H, Webster MW, Yandle TG, Espiner EA (1985). Renal, hemodynamic, and hormonal effects of human alpha atrial natriuretic peptide in healthy volunteers. Lancet 1:545PubMedCrossRefGoogle Scholar
  270. Rickards AF, Donaldson RM, Thalen HJT (1983). The use of QT-interval to determine pacing rate: early clinical experience. PACE II, 6:346CrossRefGoogle Scholar
  271. Rickards AF, Norman J (1981). Relation between QT interval and heart rate. New design of physiologically adaptive cardiac pacemaker. Br Heart J 45:56Google Scholar
  272. Ritter Ph, Daubert C, Mabo Ph, Ollitrault J, Descaves C, Gouffault J (1987). Improvement of the hemodynamic benefit of dual-chamber pacing by a rate-adapted A-V delay. PACE 10(PartII):734Google Scholar
  273. Rogel S, Mahler Y (1971). The universal pacer. A synchronized-demand pacemaker. J Thorac Cardiovas Surg 61:466Google Scholar
  274. Rognoni G, Occhetta E, Prando MD, Magnani A, Aina F, Perucca A, Bolognese L, Rossi P (1986). Benefits of rate responsive ventricular pacing with or without atrioventricular synchrony in patients with advanced or complete AVblock. In: Santini M, Pistolese M, Alliegro A (eds) Progress in cardiac pacing. Rome, p20Google Scholar
  275. Rognoni G, Magnani A, Occhetta E, Rossi P (1988). Rate responsive atrial pacing in patients with sick sinus syndrome (SSS). PACE 11 (Suppl): 827CrossRefGoogle Scholar
  276. Rokseth R, Hatle L (1974). Prospective study on the occurrence and management of chronic sinoatrial disease, with follow-up. Br Heart J 36:582PubMedCrossRefGoogle Scholar
  277. Rosado L, Tyers F, Cooper J, Kerr C (1987). Actuarial analysis of patient survival as a function of pacemaker type. PACE 10:409Google Scholar
  278. Rowe JC, White PD (1957). Complete heart block: a follow-up study. Ann Intern Med 49:260Google Scholar
  279. Rosen KM, Loeb HS, Sinno MZ, Rahimtoola SH, Gunnar RM (1971). Cardiac conduction in patients with symptomatic sinus node disease. Circulation XLIII:836Google Scholar
  280. Rosenkranz KA, Schaldach M (1971). Transvenös-endokardiale Vorhofsteuerung von Schrittmachern. Dtsch Med Wschr 96:680PubMedCrossRefGoogle Scholar
  281. Rosenquist M, Brandt J, Schüller H (1988a). Long-term pacing in sinus node disease: effects of stimulation mode on cardiovascular morbidity and mortality. Am Heart J 116(Part 1):16Google Scholar
  282. Rosenquist M, Ahren C, Nordlander R, Ryden L, Schüller H (1988b). Atrial rate-responsive pacing-effect on exercise capacity. PACE 11:514Google Scholar
  283. Rosenquist M, Obel IWB (1989). Atrial pacing and the risk for AV-block — time to change attitude? PACE in pressGoogle Scholar
  284. Rossi P, Plicchi G, Canducci G, Rognoni G, Aina F (1983). Respiratory rate as a determinant of optimal pacing rate. PACE 6 (PartII):502PubMedCrossRefGoogle Scholar
  285. Rossi P, Aina F, Rognoni G, Occhetta E, Plicchi G, Prando MD (1984). Increasing cardiac rate by tracking the respiratory rate. PACE 7:1246PubMedCrossRefGoogle Scholar
  286. Rossi P, Rognoni G, Occhetta E, Aina F, Prando MD, Plicchi G, Minella M (1985). Respiration-dependent ventricular pacing compared with fixed ventricular and atrial-ventricular synchronous pacing: aerobic and hemodynamic variables. J Am Coll Cardiol 6:646PubMedCrossRefGoogle Scholar
  287. Rossi P (1985). Biosensors: reliability and physiological specifity. In: Gomez FP (ed) Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p765Google Scholar
  288. Rossi P, Prando DM, Magnani A, Aina F, Rognoni G, Occhetta E (1988). Physiological sensitivity of respiratory-dependent cardiac pacing: four-year follow-up. PACE 11:1267PubMedCrossRefGoogle Scholar
  289. Rost W, Gattenlöhner W, Schneider KW, Stegmann N (1973). Untersuchungen zum hämodynamischem Effekt der ventrikulären, atrialen und bifokalen Stimulation. Intensivmed 11:72Google Scholar
  290. Rubenstein JJ, Schulman CL, Yurchak PM, DeSanctis RW (1972). Clinical spectrum of the sick sinus syndrome. Circulation 46:5PubMedGoogle Scholar
  291. Ruskin J, McHale PA, Harley A, Greenfield JC (1970). Pressure-flow studies in man: effect of atrial systole on left ventricular function. J Clin Invest 49:472PubMedCrossRefGoogle Scholar
  292. Russie R, Chastain S, Olive A, Pedersen B, Salo R (1988). Right ventricular impedance sensing: considerations in design of a DDDR pacemaker. PACE 11 (Suppl):797Google Scholar
  293. Ryden L (1986). The future of single chamber pacing. PACE 9 (Part II):1131PubMedCrossRefGoogle Scholar
  294. Ryden L, Karlsson Ö, Kristensson BE (1988a). The importance of different atrioventricular intervals for exercise capacity. PACE 11:1051PubMedCrossRefGoogle Scholar
  295. Ryden L (1988b). Atrial inhibited pacing — an underused mode of cardiac stimulation. PACE 11:1375PubMedCrossRefGoogle Scholar
  296. Sakai M, Ueda K, Ohkawa S, Kin H, Sugiura M (1983). Echocardiographic and pathologic studies on tricuspid regurgitation induced by transvenous right ventricular pacing. PACE 6: A-75Google Scholar
  297. Salo RW, Pederson BD, Pederson BD, Olive AL, Lincoln WC, Wallner TG (1984). Continuous ventricular volume assessment for diagnosis and pacemaker control. PACE 7:1267PubMedCrossRefGoogle Scholar
  298. Salo RW, Lincoln WC, Kadera JD (1986). The effect of VVI pacing and resultant atrioventricular dyssynchrony on segmental volumes. PACE 9 (PartII):1136PubMedCrossRefGoogle Scholar
  299. Samet Ph, Bernstein WH, Bernstein WH, Medow A, Nathan DA (1964). Effect of alteration in ventricular rate on cardiac output in complete heart block. Am J Cardiol 14:477PubMedCrossRefGoogle Scholar
  300. Santini M, Messina, G, Porto M P (1985). Sick sinus syndrome: single chamber pacing. In: Gomez FP (ed) Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p144Google Scholar
  301. Sarnoff SJ, Gilmore JP, Mitchell HH (1962). Influence of atrial contraction and relaxation on closure of the mitral valve. Circ Res 11:26PubMedGoogle Scholar
  302. Sasaki Y, Shimotori M, Akahane K, Yonekura H, Hirano K, Endoh R, Koike S, Kawa S, Furuta S, Homma T (1988). Long-term follow-up of patients with sick sinus syndrome: a comparison of clinical aspects among unpaced, ventricular inhibited paced, and physiologically paced groups. PACE 11:1575PubMedCrossRefGoogle Scholar
  303. Sauerwein HP, Roos JC, Becker AE, Dunning AJ (1976). The sick sinus syndrome. Acta med scand 199:467PubMedCrossRefGoogle Scholar
  304. Scarpelli EM, Rudolph AM (1964). The hemodynamics of congenital heart block. Prog Cardiovasc Dis 6:327PubMedCrossRefGoogle Scholar
  305. Scheibelhofer W, Kaliman J, Laczkovics A, Steinbach K (1982). Rhythm complications in atrial programmed pacing. In: Feruglio G (ed) Cardiac pacing, electrophysiology and pacemaker technology. Piccin, Padova, p471Google Scholar
  306. Scheinman MM, Peters RW, Modin G, Brennan M, Mies C, O’Young J (1977). Prognostic value of infranodal conduction time in patients with chronic bundle branch block. Circulation 56: 240PubMedGoogle Scholar
  307. Scherf D, Cohen J, Orphanus RP (1964). Retrograde activation of the atria in atrioventricular block. Am J Cardiol 13:219PubMedCrossRefGoogle Scholar
  308. Schmid P, Klein WW, Harpf H, Klein G (1969). Körperliche Belastbarkeit von Herzschrittmacherträgern. Z Kardiol 68:763Google Scholar
  309. Schuilenburg RM (1976). Pattern of V-A conduction in the human heart in the presence of normal and abnormal A-V conduction. In: Wellens HJJ, Lie KI, Janse MJ.(eds) The conduction system of the heart. Structure, function and clinical implications. Lea & Febinger, Philadelphia, p 485–503Google Scholar
  310. Schüller H, Tryding N, Westling H (1964). Die Nierenfunktion bei totalem AV-Block vor und nach Pacemakerbehandlung. Thoraxchir 12:189Google Scholar
  311. Seipel L, Pietrek G, Körfer R, Loogen F (1977). Prognose nach Schrittmacherimplantation. Internist 18:21PubMedGoogle Scholar
  312. Seipel L (1986). Atrioventrikuläre Erregungsleitung. In: Lüderitz B.(Hrsg) Herzschrittmacher. Springer, Berlin, Heidelberg, New York, Tokyo, S91CrossRefGoogle Scholar
  313. Seipel L (1987). Pharmakologische Effekte auf die intrakardiale Erregungsleitung. In: Seipel L (Hrsg) Klinische Elektrophysiologie des Herzens. Thieme, Stuttgart, New York, S149Google Scholar
  314. Segel N, Hudson WA, Harris P, Bishop JM (1964). The circulatory effects of electrically induced changes in ventricular rate at rest in during exercise in complete heart block. J Clin Invest 43:1541PubMedCrossRefGoogle Scholar
  315. Seremetis MG, deGuzman VC, Lyons WS, Peabody JW (1973). Cardiac pacemakers. Clinical experience with 289 patients. Am Heart J 85:739Google Scholar
  316. Shapland JE, MacCarter D, Tockman B, Knudson M (1983). Physiological benefits of rate responsiveness. PACE 6 (PartII):3329CrossRefGoogle Scholar
  317. Shapland JE, Bach SM, Baumann L, Lincoln B, Winkle R, Klein H (1988). New approaches for tachyarrhythmia discrimination. PACE 11 (Suppl):821Google Scholar
  318. Sharma AD, Raymond Y, Bennett T, Erickson M, Beck R, Sutton R, Klein G (1987). The effects of ventricular pacing on right ventricular maximum positive dP/dt: implications for rate responsive pacing based on this parameter. PACE 10:1228Google Scholar
  319. Shaw DB, Holman RR, Gowers JI (1980). Survival in sinoatrial disorder (sick sinus syndrome). Br Med J 1:139CrossRefGoogle Scholar
  320. Sidney KH, Shephard RJ (1977). Maximum and submaximum exercise tests in men and women in the seventh, eighth, and ninth decades of life. J Appl Physiol 43 280PubMedGoogle Scholar
  321. Simon AB, Zloto AE (1978). Atrioventricular block: natural history after permanent ventricular pacing. Am J Cardiol 41:500PubMedCrossRefGoogle Scholar
  322. Simonsen E, Nielson S, Fabricius J (1983). Atrioventricular and intraventricular conduction defects (AVCD and IVCD) in 76 patients with sinus node dysfunction (SND). His bundle study in selection of pacing mode. PACE 6A-1:3Google Scholar
  323. Skagen K, Hansen JF (1975). The long-term prognosis for patients with sinoatrial block treated with permanent pacemaker. Acta Scand Med 199:13CrossRefGoogle Scholar
  324. Skinner NS, Mitchell J, Wallace AT, Sarnoff SJ (1963). Hemodynamic effects of altering the time of atrial systole. Am J Physiol 205:499PubMedGoogle Scholar
  325. Smedgard P, Kristensson BE, Kruse I, Ryden L (1987). Rate responsive pacing by means of activity sensing versus single rate ventricular pacing: a double blind cross-over study. PACE 10 (PartI):902PubMedCrossRefGoogle Scholar
  326. Smyth MNP, Citron P, Keshishian JM, Garcia JM, Kelly LC (1976). Permanent pervenous atrial sensing with a new J-shaped lead. J Thorac Cardiovasc Surg 72:565PubMedGoogle Scholar
  327. Sonnenblick EH, Braunwald E, Williams JF, Glick G (1965). Effects of exercise on myocardial force-velocitiy relations in intact unaestetized man: relative roles of changes in heart rate, sympathetic activity, and ventricular dimensions. J Clinical Invest 44:2051CrossRefGoogle Scholar
  328. Sowton E (1964). Hemodynamic studies in patients with artificial pacemakers. Br Heart J 26:737PubMedCrossRefGoogle Scholar
  329. Sowton E (1967). The relationship between maximal oxygen uptake and heart rate in patients with artificial pacemakers. Cardiologia 50:15PubMedCrossRefGoogle Scholar
  330. Sowton E, Flores J (1971). Natural history of pacemaker patients. Bull NY Acad Med 47:999Google Scholar
  331. Spencer WH, Goodman DA, Hargis J, Westley V, Lin HT (1987). Comparison of exercise performance in three rate-responsive pacing modes. PACE 10:1229Google Scholar
  332. Stack M F, Rader B, Sobol B J, Färber S J, Eichna L W (1958). Cardiovascular hemodynamic functions in complete heart block and the effect of isopropylnorepinephrine. Circulation 17:526PubMedGoogle Scholar
  333. Stangl K, Wirtzfeld A, Göbl G, Heinze R, Laule M, Seitz K, Lochschmidt O (1986). Rate control with an external SO2 closed loop system. PACE 9 (PartII):992PubMedCrossRefGoogle Scholar
  334. Stangl K, Wirtzfeld A, Seitz K, Alt E, Blömer H (1987). Atrial stimulation (AAI): Longterm follow up of 110 patients. In: B. Belhassen, S. Feldmann, Y. Copperman (eds) Cardiac pacing and electrophysiology. R&L Creative Communications Ltd, Jerusalem, p283Google Scholar
  335. Stangl K, Munteanu J, Wirtzfeld A (1987). Right atrial pressure, right ventricular pressure and dP/dt: new parameters for regulating rate response in pacemakers. PACE 10:1230Google Scholar
  336. Stangl K, Wirtzfeld A, Heinze R, Laule M, Seitz K, Göbl G (1988a). A new multisensor pacing system using stroke volume, respiratory rate, mixed venous oxygen saturation, and temperature, right atrial pressure, right ventricular pressure, and dP/dt. PACE 11:712PubMedCrossRefGoogle Scholar
  337. Stangl K, Weil J, Seitz K, Laule M, Gerzer R (1988b). Influence of AV-synchrony on the plasma levels of atrial natriuretic peptide (ANP) in patients with total AV-block. PACE 11:1176PubMedCrossRefGoogle Scholar
  338. Starling EH (1915). The lineacre lecture on the law of the heart. Longmans, CambridgeGoogle Scholar
  339. Steinbeck G, Lüderitz B (1977). Störungen der Sinusknotenfunktion. Diagnostik und klinische Bedeutung. Dtsch Med Wschr 102:35PubMedCrossRefGoogle Scholar
  340. Steinbach K, Frohner K, Meisl F, Podczek A, Unger G (1985). Atrial Stimulation. In: Gomez FP (ed) Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p629Google Scholar
  341. Stephenson SE, Jolly PC, Bailey HW, Edwards WH, Montgomery LH (1959). Evaluation of P-wave external cardiac stimulation. Surg Forum 10:612Google Scholar
  342. Stewart, WJ, Dicola VC, Harthorne JW, Gillam LD, Weyman AE (1984). Doppler ultrasound measurement of cardiac output in patients with physiological pacemakers. Effects of left ventricular function and retrograde ventriculo-atrial conduction. Am J Cardiol 54:308Google Scholar
  343. Stone JM, Bhakta RD, Lutgen J (1982). Dual chamber sequential pacing in the management of sinus node dysfunction: advantages over single-chamber pacing. Am Heart J, 104:1319PubMedCrossRefGoogle Scholar
  344. Sugiura T, Kimura M, Mizushina S, Yoshimura K, Harada Y (1988). Cardiac pacemaker regulated by respiratory rate and blood temperature. PACE 11:1077PubMedCrossRefGoogle Scholar
  345. Sutton R, Citron P (1979). Electrophysiological and hemodynamic basis for application of new pacemaker technology in sick sinus syndrome and atrioventricular block. Br Heart J, 41:600PubMedCrossRefGoogle Scholar
  346. Sutton R, Perrins, H Citron P (1980). Physiological cardiac pacing. PACE 3:207PubMedCrossRefGoogle Scholar
  347. Sutton R, Perrins EJ, Morley C, Chan SL (1983). Sustained improvement in exercise tolerance following physiological cardiac pacing. Eur Heart J 4:781PubMedGoogle Scholar
  348. Sutton R, Kenny RA (1986). The natural history of sick sinus syndrome. PACE 9 (PartII):1110PubMedCrossRefGoogle Scholar
  349. Sutton R (1988). When and how to pace in the sick sinus syndrome. In: Santini M, Pistolese M, Alliegro A (eds) Progress in clinical pacing. Excerpta Medica, Amsterdam, Hong Kong, Manila, Princeton, Sydney, Tokyo, p183Google Scholar
  350. Swift PC, Cowell LC, Woolard KV (1987). A comparison of the exercise response to DDD and activity response ventricular pacing. PACE 10(PartII):751Google Scholar
  351. Täuber K, Wallnöfer H (1983). M-mode echocardiography — A diagnostic tool for detection and prevention of PM-syndrome? PACE 6: A-87Google Scholar
  352. Thormann H, Paeprer H, Nassen M (1975). Langzeiterfahrung mit der Schrittmacherbehandlung bradykarder Rhythmusstörungen. Herz Kreisl 7:144Google Scholar
  353. Torresani J, Bernard Y, Monties JR, Jouve A (1969). Clinical experience in transvenous and myocardial pacing. Ann NY Acad Sci 167:995PubMedCrossRefGoogle Scholar
  354. Trappe HJ, Klein H, Frank G, Lichtlen PR (1988). Rate responsive pacing as compared to fixed rate VVI pacing in patients after ablation of the atrioventricular conduction system. Eur Heart J 9:642PubMedGoogle Scholar
  355. Travill CM, Vardas P, Ingram A, Lightman SL, Sutton R (1988). Benefits of VVIR over VVI: Atrial natriuretic peptide (ANP) — a new quantitative assessment? PACE 11 (Suppl):860Google Scholar
  356. Treese H, Jungfleisch S, Rhein S, Nixdorf U, Geeren M, Pop T, Meyer J (1988). Cardiopulmonary exercise: a new approach for control of rate responsive pacing. PACE 11 (Suppl):847Google Scholar
  357. Tscheliessnigg KH, Stenzl W, Dacar D, Iberer F (1985). Hemodynamic importance of a constant A-V delay. In: Gomez FP (ed) Cardiac pacing, electrophysiology, tachyarrhythmias. Editorial Grouz, Madrid, p572Google Scholar
  358. Unger G, Biolonozyk C, Leonhartsberger H, Köhn H, Meisl F, Mostbeck A, Steinbach K (1983). Influence of pacing mode on parameters of left ventricular function (LVF) measured by Tc-nucleid-ventriculography (Tc-N). PACE 6:A-80Google Scholar
  359. Vallin H, Edhag O (1981). Associated conduction disturbances in patients with symptomatic sinus node disease. Acta med scand 210:263PubMedCrossRefGoogle Scholar
  360. Van Mechelen R, Hagemeijer F, de Boer H, Schelling A (1983). Atrioventricular and ventriculo-atrial conduction in patients with symptomatic sinus node dysfunction. PACE 6:13PubMedCrossRefGoogle Scholar
  361. Van Mechelen R, Segers A, Hagemeijer F (1984). Serial electrophysiologic studies after single chamber atrial pacemaker implantation in patients with symptomatic sinus node dysfunction. Eur Heart J 5:628PubMedGoogle Scholar
  362. Vardas P, Williams M, Travill C, Lightman S, Sutton R (1987). Atrial natriuretic peptide in complete atrioventricular block, untreated and after DDD and VVI pacing. In: B. Beihassen, S. Feldman, Y. Copperman (eds). Cardiac pacing and electrophysiology. R&L Creative Communications Ltd, p261Google Scholar
  363. Velimirovic YD, Djordjevic M, Kocovic D, Pavlovic S, Stojanov P, Jelic V (1988). Metabolic and hemodynamic assessments of rate responsive pacing: a comparative study. PACE 11 (Suppl):851Google Scholar
  364. Vera Z, Mason DT, Awan NA, Miller RR, Janzen D, Tonkon MJ, Vismara LA (1977). Improvement of symptoms in patients with sick sinus syndrome by spontaneous development of stable atrial fibrillation. Br Heart J 39:160PubMedCrossRefGoogle Scholar
  365. Videen JS, Huang SK, Bazgan ID, Mechling E, Patton DD (1986). Hemodynamic comparison of ventricular pacing, atrioventricular sequential pacing and atrial synchronous ventricular pacing using radionuclide ventriculography. Am J Cardiol 57:1305PubMedCrossRefGoogle Scholar
  366. Vogt P, Goy JJ, Kuhn M, Leuenberger P, Sigwart, H Kappenberger L (1988). Single versus double chamber rate responsive pacing: comparison by cardiopulmonary exercise testing. PACE 11 (Suppl):797CrossRefGoogle Scholar
  367. Bibra H, Busch U, Wirtzfeld A (1984). Hemodynamic effects of short AV-intervals in DDD pacemaker patients. Circulation 70:408Google Scholar
  368. Vreuls PJM, Boute W, Begemann MJS (1988). Advantages of rate dependent atrioventricular interval on general functioning of a dual chamber pacemaker. PACE 11 (Suppl):816Google Scholar
  369. Wallner H, Prabhu R, Brown C (1981). Long-term follow-up of J-shaped tined permanent pacing lead. Chest 80:346CrossRefGoogle Scholar
  370. Walsh KP, Ingram A, Kenny RA, Vardas PE, Sutton R (1985). Long term results of atrial pacing. PACE 8:789Google Scholar
  371. Weisswange A, Csapo G, Perach W, Kannegießer B (1978). Frequenzsteuerung von Schrittmachern durch Bluttemperatur. Verh Dtsch Ges Kreislaufforsch 44:152CrossRefGoogle Scholar
  372. Wessale JL, Geddes LA, Fearnot NE, Janas W, Grote LA (1988). Cardiac output versus pacing rate at rest and with exercise in dogs with AV block. PACE 11:575PubMedCrossRefGoogle Scholar
  373. Westermann KW (1972). Hämodynamische Untersuchungen bei Schrittmacherträgern während AV-Block, starrfrequenter und vorhofgesteuerter Stimulation. Intensivmed 9:360Google Scholar
  374. Westveer DC, Stewart JR, Goodfleish R, Gordon S, Timmis GC (1984). Prevalence and significance of ventriculo-atrial conduction. PACE 7:184CrossRefGoogle Scholar
  375. White JK, Leman RB, Kratz J, Gillette P (1988). Utility of rate responsive pacing in DDD pacemakers. PACE 11:500Google Scholar
  376. Winters WL, Tyson RR, Barrera F, Soloff LA (1965). Cardiac pacemaking. Physiological studies. Ann Intern Med 62: 220Google Scholar
  377. Wirtzfeld A, Sebening H (1973). Das Sinusknotensyndrom. Dtsch med Wschr 98:1PubMedCrossRefGoogle Scholar
  378. Wirtzfeld A, Himmler FC, Präuer HW, Klein G (1979). Atrial and ventricular pacing in patients with the sick sinus syndrome. In: Meere CM (ed) Cardiac pacing. Proceedings of the VIth World Symposion on Cardiac Pacing, Chap. 15–25Google Scholar
  379. Wirtzfeld A, Goedel-Meinen L, Bock T, Heinze R, Ließ HD, Munteanu J (1981a). Central venous oxygen saturation for the control of automatic rate-responsive pacing. Circulation 64:Suppl IV, 299Google Scholar
  380. Wirtzfeld A, Himmler FC, Blömer H (1981b). Klinische Gesichtspunkte der Schrittmachertherapie bradykarder Herzrhythmusstörungen. Verh Dtsch Ges Kreislaufforsch 47:98Google Scholar
  381. Wirtzfeld A, Himmler FC, Klein G, Schmidt G, Seidel K, Alt E, Präuer HW (1982a). Atrial pacing in patients with sick sinus syndrome: acute and long-term hemodynamic effects. In: Feruglio G (ed) Cardiac pacing. Piccin, Padova, p651.Google Scholar
  382. Wirtzfeld A, Goedel-Meinen L, Bock T, Heinze R, Liess HD, Munteanu J (1982b). Central venous oxygen saturation for the control of automatic rate-responsive pacing. PACE 5:829PubMedCrossRefGoogle Scholar
  383. Wirtzfeld A, Schmidt G, Himmler FC, Stangl K (1987). Physiological pacing: present status and future developments. PACE 10:41PubMedCrossRefGoogle Scholar
  384. Wirtzfeld A, Stangl K, Maubach P (1988). Indications, non-indications and contraindications for rate responsive pacing. In: Santini M, Pistolese M, Alliegro A (eds) Progress in clinical pacing. Excerpta Medica Amsterdam, Hong Kong, Manila, Princeton, Sydney, Tokyo, p51Google Scholar
  385. Witte J, Dressler L, Schröder G (1979). 10 years of experience with permanent atrial electrodes. In: Meere CM (ed) Cardiac pacing. Proceedings of the VIth World Symposion on Cardiac Pacing, Chap. 16-1Google Scholar
  386. Witte J, Bondke HJ, Hauptvogel D (1987). Rate responsive AAI pacing-a reliable concept of „physiological pacing“ in sick sinus syndrome involving few complications and little cost. PACE 10:1233Google Scholar
  387. Wohl AJ, Laborde NJ, Atkins JM, Blomquist G, Mullins CB (1976). Prognosis of patients permanently paced for sick sinus syndrome. Arch Intern Med 136:406PubMedCrossRefGoogle Scholar
  388. Yee R, Benditt DG, Kostüm WJ, Ko PT, Purves P, Klein GJ (1984). Comparative functional effects of chronic ventricular demand and atrial synchronous ventricular inhibited pacing. PACE 7:23PubMedCrossRefGoogle Scholar
  389. Zegelman M, Cieslinsky G, Kreuzer J, Ciaaßen K (1987a). 140 times body activity directed pacing — non-physiological sensor with satisfying clinical results? PACE 10:1234Google Scholar
  390. Zegelman M, Kreuzer J, Cieslinski G, Boll C, Beyersdorf F (1987b). 35 times respiratory dependent pacing-hemodynamic and clinical results, rate response in comparison to DDD. PACE 10:1234Google Scholar
  391. Ziljstra F, Polak PE, Tanis CJ, Perk R (1987). Comparison of two pacing modes of rate responsive pacing. In: B. Belhassen, S. Feldman, Y. Copperman (eds) Cardiac pacing and electrophysiology. R&L Creative Communications Ltd, Jerusalem, p133Google Scholar
  392. Zion MM, Marchand PE, Obel IWP (1973). Long-term prognosis after cardiac pacing in atrioventricular block. Br Heart J 35:359PubMedCrossRefGoogle Scholar
  393. Zipes DP, Festoff B, Schaal SF, Cox C, Sealy WC, Wallace AB (1968). Treatment of ventricular arrhythmia by permanent atrial pacemaker and cardiac sympathectomy. Ann Intern Med 68:591PubMedGoogle Scholar
  394. Zoll PM, Frank HA, Linenthal H (1964). Four-year experience with an implanted cardiac pacemaker. Ann Surg 160:351PubMedCrossRefGoogle Scholar

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