Abstract
The major effort in molecular biology during the last two decades was to explain the structure and function of the eucaryotic genome. The investigators were able to establish a variety of recombinant DNA techniques which have a great potential for the application in animal breeding. cDNA- and genomic DNA-libraries and gene transfer techniques are the most important tools to diagnose and manipulate the genome. The first indication for possible application of gene transfer was successful expression of the MMT-growth hormone fusion gene in transgenic mice [7], but the following experiments in rabbits, pigs, sheep, and cattle [2, 4, 1] reduced the great expectations. The recent data about controlled, tissue specific expression of the transferred milk protein gene for ovine β-lactoglobulin [8] in mice suggest that manipulation of milk composition and changing of technological properties of milk proteins could be of interest for practical animal breeding [3].
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© 1989 Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt
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Dovč, P., Elbertzhagen, H., Niepold, F., Rottmann, O.J. (1989). Expression of the Bovine α s1 — Casein cDNA in CHO Cells. In: Barth, C.A., Schlimme, E. (eds) Milk Proteins. Steinkopff. https://doi.org/10.1007/978-3-642-85373-9_26
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DOI: https://doi.org/10.1007/978-3-642-85373-9_26
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