Abstract
The treatment of patients with mild hypertension has created considerable interest in recent years. The availability of many potent antihypertensive agents allows blood pressure to be effectively controlled without major adverse effects. It is believed that control of even mild elevations of blood pressure significantly reduces the incidence of major cardiovascular complications.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ashraf N, Locksley R, Arieff AI (1981) Thiazide-induced hyponatraemia associated with death or neurologic damage in outpatients. Am J Med 70: 1163–1168.
Barrett-Connor E, Criqui MH, Klauber MR, Holdbrook M (1981) Diabetes and hypertension in a community of older adults. Am J Epidemiol 113: 276–284.
Beretta-Piccoli C, Davies DL, Boddy K et al (1982) Relation of arterial pressure with body sodium, body potassium and plasma potassium in essential hypertension. Clin Sci 63: 257–270.
Bühler FR, Burkart F, Lütold BE, Küng M, Marbet G, Pfisterer M (1975) Antihypertensive beta-blocking action as related to renin and age: a pharmacologic tool to identify pathogenetic mechanisms in essential hypertension. Am J Cardiol 36: 653–669.
Bühler FR, Kiowski W, Landmann R et al. (1982) Changing role of beta-and alpha-adrenoreceptor-mediated cardiovascular responses in the transition from high-cardiac output into a high-peripheral resistance phase in essential hypertension. In: Largh JH, Bühler F, Seldin D (Eds.) Frontiers in Hypertension Research, Springer-Verlag, New York, 316–326.
Drayer JIM, Weber MA, Laragh JH, Sealey JE (1982) Renin subgroups in essential hypertension. Clin Exp Hypertens A4: 1817–1834.
Drayer JIM, Weber MA, Sealey JE, Laragh JH (1981) Low and high renin essential hypertension: a comparison of clinical and biochemical characteristics. Am J Med Sci 281: 135–142.
Drayer JIM, Weber MA, Sealey JE, Laragh JH (submitted for publication 1983 ). Comparison of clinical characteristics of patients with systolic and diastolic hypertension.
Kannel WB (1974) Role of blood pressure in cardiovascular morbidity and mortality. Prog Cardiovasc Dis 17: 5–24.
Kannel WB, Dawber TR, McGee DL (1980) Perspectives on systolic hypertension. The Framingham Study. Circulation 61: 1179–1182.
Kannel WB, Gordon T, Castelli WP, Margolis JR (1970) Electrocardiographic left ventricular hypertrophy and risk of coronary heart disease. The Framingham Study. Ann Intern Med 72: 813–822.
Messerli FH, Gerald MD, Dreslinski GR (1981 b) Antiadrenergic therapy: special aspects in hypertension in the elderly. Hypertension 3 (Suppl II ): 226–239.
Messerli FH, Glade LB, Dreslinski GR et al (1981 a) Hypertension in the elderly: haemodynamic, fluid volume and endocrine findings. Clin Sci 61: 393s - 394s.
Multiple Risk Factor Intervention Trial Research Group (1982) Multiple risk factor intervention trial. Risk factor changes and mortality, results. JAMA 2481: 1465–1477.
Niarchos AP (1980) Pathophysiology, diagnosis, and treatment of hypertension in the elderly. Cardiovasc Rev Rep 1: 621–627.
Norwegian Multicenter Study Group (1981) Timolol-induced reduction in mortality and re-infarction in patients surviving acute myocardial infarction. N Engl J Med 304: 801–807.
Palmer GJ, Ziegler MG, Lake CR (1978) Response of norepinephrine and blood pressure to stress increases with age. J Gerontol 33: 482–487.
Schocken DD, Roth GS (1977) Reduced beta-adrenergic receptor concentrations in aging man. Nature 267: 856–865.
Stebbins PT, Taylor GJ, Gibson RS, Beller GA (1980) Risk factors and myocardial infarction in the elderly. Circulation 62 (Suppl III): 220–230.
Thananopavarn C, Golub MS, Sambhi MP (1983) Clonidine in the elderly hypertensive. Monotherapy and therapy with a diuretic. Chest 2 (Suppl): 410–411.
Weber MA, Drayer JIM, Gray DR (1983) Combined diuretic and sympatholytic therapy in elderly patients with predominant systolic hypertension. Chest 2 (Suppl): 416–419.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1984 Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG, Darmstadt
About this paper
Cite this paper
Drayer, J.I.M., Weber, M.A. (1984). Use of centrally-acting agonists in the treatment of mild hypertension in the elderly patient. In: Weber, M.A., Mathias, C.J. (eds) Mild Hypertension. Steinkopff. https://doi.org/10.1007/978-3-642-85334-0_10
Download citation
DOI: https://doi.org/10.1007/978-3-642-85334-0_10
Publisher Name: Steinkopff
Print ISBN: 978-3-642-85336-4
Online ISBN: 978-3-642-85334-0
eBook Packages: Springer Book Archive