Long-Term Effects of High-Dose ISDN Therapy in Patients with Coronary Heart Disease
The present study was designed to determine whether a dose-response relationship exists in the treatment of angina pectoris with oral isosorbide dinitrate (ISDN) and to investigate the possible development of tolerance to the antianginal effects of ISDN during therapy with 480 mg per day (see Fig. 1–4).
KeywordsPlacebo Depression Attenuation Lactate Nitroglycerin
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