Macrophage-Silicone Interactions in Women with Breast Prostheses
In order for silicone from breast implants to have an effect on the immune system, it must be demonstrated that cells with the potential for immune system function have access to silicone. It had long been thought that the fibrous capsule surrounding breast prostheses functioned as an effective barrier between the biomaterial and the host. Implants that ruptured were thought to be innocuous to the host as long as the fibrous tissue capsule surrounding the implant was intact. This was termed “contained rupture.” Thus, the capsule was thought to prevent the egress of foreign material (Bingham et al. 1988)
KeywordsForeign Material Breast Implant Silicone Breast Implant Capsular Tissue Breast Prosthesis
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