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Malignant Lymphoma and Multiple Myeloma

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Part of the book series: UICC International Union Against Cancer ((UICCI))

Abstract

Lymphomas are malignant diseases arising from uncontrolled proliferation of lymphatic cells. Such cells are primarily located in lymph nodes; thus, enlargement of lymph nodes is the most common symptom. Because of the wide distribution of lymphatic tissue throughout the body, lymphomas may also arise in extranodal and extralymphatic sites such as brain, lungs, stomach, testes, and bones. Extralymphatic tissues may be involved by contiguous extension of disease from nodal sites (E lesions) or by hematogenous spread in advanced stages.

The section “Malignant Lymphoma” was written by D.K. Hossfeld, and the section “Multiple Myeloma” by D.K. Hossfeld and H.J. Weh.

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Further Reading

Malignant Lymphoma

  • Canellos GP, Anderson JR, Propert KJ, Nissen N, Cooper MR, Henderson ES, Green MR, Gottlieb A, Peterson BA (1992) Chemotherapy of advanced Hodgkin’s disease with MOPP, ABVD, or MOPP alternating with ABVD. New England Journal of Medicine 827: 1478–1484

    Article  Google Scholar 

  • De Bruin PC, Noorduyn AL, van der Valk P, van Heerde P, van Diest PJ, van de Sandt MM, Ossenkoppele GJ, Meijer CJLM (1993) Noncutaneous T-cell lymphomas. Recognition of a lymphoma type (large cell anaplastic) with a relatively favorable prognosis. Cancer 71: 2604–2612

    Article  PubMed  Google Scholar 

  • Fisher RJ, Gaynor ER, Dahlberg S, Oken MM, Grogan TM, Mize EM, Glick JH, Coltman CA, Miller TP (1993) Comparison of a standard regimen ( CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin’s lymphoma. New England Journal of Medicine 328: 1002–1006

    Article  CAS  PubMed  Google Scholar 

  • Foss Abrahamsen J, Andersen A, Hannisdal E, Nome O, Foss Abrahamsen A, Kvaloy S, Host H (1993) Second malignancies after treatment of Hodgkin’s disease: the influence of treatment, follow-up, and age. Journal of Clinical Oncology 11: 255–261

    Google Scholar 

  • Herbst H, Steinbrecher E, Niedobitek G, Young LS, Brooks L, Müller-Lantzsch N, Stein H (1992) Distribution and phenotype of Epstein-Barr virus-harboring cells in Hodgkin’s disease. Blood 80: 484–491

    CAS  PubMed  Google Scholar 

  • Kondo E, Nakamura S, Onoue H, Matsuo Y, Yoshino T, Aoki H, Hayashi K, Takahashi K, Minowada J, Nomura S, Akagi T (1992) Detection of bc1–2 protein and bc1–2 messenger RNA in normal and neoplastic lymphoid tissues by immunohistochemistry and in situ hybridization. Blood 80: 2044–2051

    CAS  PubMed  Google Scholar 

  • Levine AM (1992) Acquired immunodeficiency syndrome-related lymphoma. Blood 80: 8–20

    CAS  PubMed  Google Scholar 

  • Mauch PM, Kalish LA, Kadin M, Coleman CN, Osteen R, Hellman S (1993) Patterns of presentation of Hodgkin’s disease. Implications for etiology and pathogenesis. Cancer 71: 2062–2071

    Article  Google Scholar 

  • Portlock CS (1990) Management of the low-grade non-Hodgkin’s lymphomas. Seminars in Oncology 17: 51–59

    CAS  PubMed  Google Scholar 

  • Urba WJ, Longo DL (1992) Hodgkin’s disease. New England Journal of Medicine 326: 678–687

    Article  CAS  PubMed  Google Scholar 

  • Yi PI, Coleman M, Saltz L, Norton L, Topilow AA, Adler K, Bernhardt B (1990) Chemotherapy for large cell lymphoma: a status update. Seminars in Oncology 17: 60–73

    CAS  PubMed  Google Scholar 

Multiple Myeloma

  • Alexanian R, Dimopoulos M (1994) The treatment of multiple myeloma. New England Journal of Medicine 330: 484–489

    Article  CAS  PubMed  Google Scholar 

  • Gregory WM, Richards MA, Malpas JS (1992) Combination chemotherapy versus melphalan and prednisolone in the treatment of multiple myeloma: an overview of published trials. Journal of Clinical Oncology 10: 334–342

    CAS  PubMed  Google Scholar 

  • Hjorth M, Hellquist L, Holmberg E, Magnusson B, Rödjer S, Westin J (1990) Initial treatment in multiple myeloma: no advantage of multidrug chemotherapy over melphalan-prednisone. British Journal of Haematology 74: 185–191

    Article  CAS  PubMed  Google Scholar 

  • Lichtenstein A, Berenson J, Norman D, Chang MP, Carlile A (1989) Production of cytokines by bone marrow cells obtained from patients with multiple myeloma. Blood 74: 1266–1273

    CAS  PubMed  Google Scholar 

  • Niesvizky R, Siegel D, Michaeli J (1993) Biology and treatment of multiple myeloma. Blood Review 7: 24–33

    Article  CAS  Google Scholar 

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© 1994 Springer-Verlag Berlin Heidelberg

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Hossfeld, D.K., Weh, H.J. (1994). Malignant Lymphoma and Multiple Myeloma. In: Love, R.R. (eds) Manual of Clinical Oncology. UICC International Union Against Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85159-9_33

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  • DOI: https://doi.org/10.1007/978-3-642-85159-9_33

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-58193-2

  • Online ISBN: 978-3-642-85159-9

  • eBook Packages: Springer Book Archive

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