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Cellular and Molecular Biology of Cancer

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Part of the book series: UICC International Union Against Cancer ((UICCI))

Abstract

Cancer is a generic term used to describe over 200 individual diseases. These diseases progress differently over time but share certain characteristics. These characteristics include development within any tissue of a malignant growth derived from abnormal cells of the host. The abnormal cells proliferate autonomously, invade through normal tissue barriers, spread to local and distant tissue sites, and reproduce indefinitely. The masses of abnormal cells formed and spread in this way lead to the death of the host if not eradicated. (The word “cancer” comes from the Latin, meaning crab. A tumor was called a cancer because of swollen veins around the area resembling a crab’s limbs.)

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Further Reading

  • Druker BJ, Mamon HJ, Roberts TM (1989) Oncogenes, growth factors and signal transduction. New England Journal of Medicine 321: 1383–1391

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  • Pitot HC (1993) The molecular biology of carcinogenesis. Cancer 72:962–970

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  • Tannock IF, Hill RP (eds) (1993) The basic science of oncology. Pergamon, New York

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  • Weinberg RA (1989) Oncogenes, anti-oncogenes and the molecular basis of multistep carcinogenesis. Cancer Research 49: 3713–3721

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© 1994 Springer-Verlag Berlin Heidelberg

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Love, R.R. (1994). Cellular and Molecular Biology of Cancer. In: Love, R.R. (eds) Manual of Clinical Oncology. UICC International Union Against Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85159-9_1

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  • DOI: https://doi.org/10.1007/978-3-642-85159-9_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-58193-2

  • Online ISBN: 978-3-642-85159-9

  • eBook Packages: Springer Book Archive

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