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Nerve Growth Factor: Optic and Ultrastructural Findings on Facial Nerve Degeneration in the Rabbit

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The Facial Nerve

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Abstract

After the discovery by Hamburger [3] and Levi-Montalcini [5] of the nerve growth factor (NGF), other neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and cilliary neurotrophic factor (CNTR) [6] were found. At present we do not know whether a specific trophic factor exists that acts on motor fibers. On the other hand, the effect of the NGF on sensory fibers is known. Therefore, we used this factor locally on the transected area of a mixed nerve, such as the facial nerve, evaluating its possible action during the degeneration period.

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References

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Author information

Authors and Affiliations

  1. Department of Otolaryngology, Hospital Central Universitario de Asturias, c/Pedro Masaveu 25, 33007, Oviedo, Asturias, Spain

    M. J. Bernardo, C. Suarez & J. L. Llorente

  2. Department of Pathology, Hospital Central Universitario de Asturias, c/Pedro Masaveu 25, 33007, Oviedo, Asturias, Spain

    P. Ablanedo

  3. Department of Cellular Biology, Hospital Central Universitario de Asturias, c/Pedro Masaveu 25, 33007, Oviedo, Asturias, Spain

    M. Alvarez-Uria

Authors
  1. P. Ablanedo
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  2. M. J. Bernardo
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  3. C. Suarez
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  4. M. Alvarez-Uria
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  5. J. L. Llorente
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Editor information

Editors and Affiliations

  1. Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Universität zu Köln, Joseph-Stelzmann-Str. 9, D-50924, Köln, Germany

    E. R. Stennert

  2. Max-Planck-Institut für Psychiatrie und Neuromorphologie, Am Klopferspitz 18a, D-82152, Martinsried, Germany

    G. W. Kreutzberg

  3. Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Joseph-Stelzmann-Str. 9, D-50924, Köln, Germany

    O. Michel (Ltd. Oberarzt) & M. Jungehülsing (Wiss. Mitarbeiter) (Ltd. Oberarzt) &  (Wiss. Mitarbeiter)

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© 1994 Springer-Verlag

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Ablanedo, P., Bernardo, M.J., Suarez, C., Alvarez-Uria, M., Llorente, J.L. (1994). Nerve Growth Factor: Optic and Ultrastructural Findings on Facial Nerve Degeneration in the Rabbit. In: Stennert, E.R., Kreutzberg, G.W., Michel, O., Jungehülsing, M. (eds) The Facial Nerve. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85090-5_164

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  • DOI: https://doi.org/10.1007/978-3-642-85090-5_164

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-57686-0

  • Online ISBN: 978-3-642-85090-5

  • eBook Packages: Springer Book Archive

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