Abstract
Fungal infections are not the most common infections in intensive care unit (ICU) patients but they often represent a most serious complication. Data collected by the NNIS (National Nosocomial Surveillance System) in the United States pointed out that 8% of all nosocomial infections between 1980 and 1990 were caused by fungi; Candida spp. accounted for almost 80% of these fungal isolates [1]. The reported mortality among patients with candidemia ranged from 60% to 80% overall. In long-time ICU patients isolation of Candida spp. in tracheal secretions, urine and serum is a frequent microbiological finding but the clinical significance is not yet clear.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Jarvis WR et al (1992) 3rd international conference on nosocomial infections, Atlanta
Wong-Beringer A, Jacobs RA, Guglielmo BJ (1992) Treatment of funguria. JAMA 267:2780–2785
Horn R, Wong B, Kiehn TE, Armstrong D (1985) Fungemia in a cancer hospital: changing frequency, earlier onset and results of therapy. Rev Infect Dis 7:646–655
Maksymiuk AW, Thongprasert S, Hopfer R, Luna M, Fainstein V, Bodey GP (1984) Systemic candidiasis in cancer patients. Am J Med 77:20–27
Odds FD (1979) Candida and candidosis. University Park Press
Andersen LI, Frederiksen HJ, Appleyard M (1992) Prevalence of esophageal Candida colonization in a Danish population: special reference to esophageal symptoms. Benign esophageal disorders and pulmonary disease. J Infect Dis 165:389–392
Edwards JE (1989) Candidemia and Candida catheter-associated sepsis. In: Holmberg K, Meyer RD (eds) Diagnosis and therapy of systemic fungal infections. Raven, New York pp 39–46
Fussle R, Biscoping D, Zeiler D, Michaelis G, Sziegoleit A (1991) Mikrobiologische Betreuung von beatmeten Intensivpatienten. Anaesthesist 91:491–496
Fräser VJ, Jones M, Dunkel J, Storfer S, Medoff G, Dunagan WC (1992) Candidemia in a tertiary hospital: epidemiological risk factors and predictors of mortality. Clin Infect Dis 15:414–421
Thales M, Tastakia B, Shawker TH et al (1988) Hepatic candidiasis in cancer patients: the evolving picture of the syndrome. Ann Intern Med 108:88–100
Petri M, Moecke HP, Gramm HJ et al (1993) Epidemiologie invasiver Mykosen auf Intensivstationen. 2. Deutscher Konreβ für Infektions-und Tropenmedizin
Bodey GP, Vartivarian S (1989) Aspergillosis. Eur J Microbiol Infect Dis 8:413–437
Kurup VP, Kumar A (1991) Immunodiagnosis of Aspergillosis. Clin Microbiol Rev 4:439–456
Wheat LJ (1993) The role of the serologic diagnostic laboratory and the diagnosis of fungal disease. In: Sarosi GE, Davies FD (eds) Fungal diseases of the lung, 2nd edn. Raven, New York pp 29–38
Anaissia E, Kontoyiannas C, Hüls C, Prince R, Bosso JA, Bodey GP (1993) Efficacy, safety and pharmakokinetics of high dose fuconazol in patients with fungal infections. Z Chemother 1:6 (abstract)
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Petri, M., Lode, H., Schaberg, T. (1994). Diagnostic and Therapeutic Approach in Invasive Fungal Infections of Intensive Care Unit Patients. In: Reinhart, K., Eyrich, K., Sprung, C. (eds) Sepsis. Update in Intensive Care and Emergency Medicine, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85036-3_20
Download citation
DOI: https://doi.org/10.1007/978-3-642-85036-3_20
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-85038-7
Online ISBN: 978-3-642-85036-3
eBook Packages: Springer Book Archive