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Sepsis pp 174–180Cite as

Endothelial Cell Function in the Critically Ill

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Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 18))

Abstract

Our concepts have changed markedly since W. Harvey’s original description of the vasculature as a passive conduit for blood to the vital organs. The endothelium of the vasculature represents a complex organ synthesizing a number of mediators and interacting actively with other cellular elements including circulating white blood cells and platelets and infiltrating macrophages. The endothelium can directly influence the vascular smooth muscle, thereby regulating the distribution of blood flow to the cells. The total endothelium surface area is estimated to cover six tennis courts and to weigh 1–1.5 kg in an adult.

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Authors
  1. J.-L. Vincent
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  2. J. C. Preiser
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  3. G. Friedman
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  4. H. Zhang
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Editor information

Editors and Affiliations

  1. Klinik für Anästhesiologie und Intensivtherapie, Klinikum der Friedrich Schiller-Universität Jena, Bachstraße 18, 07740, Jena, Germany

    Konrad Reinhart

  2. Klinik für Anästhesiologie und operative Intensivmedizin, Universitätsklinikum Steglitz der FU Berlin, Hindenburgdamm 30, 12200, Berlin, Germany

    Klaus Eyrich

  3. Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University, Medical Center, P. O. Box 12000, 91120, Jerusalem, Israel

    Charles Sprung (Direktor) (Direktor)

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© 1994 Springer-Verlag Berlin Heidelberg

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Vincent, JL., Preiser, J.C., Friedman, G., Zhang, H. (1994). Endothelial Cell Function in the Critically Ill. In: Reinhart, K., Eyrich, K., Sprung, C. (eds) Sepsis. Update in Intensive Care and Emergency Medicine, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85036-3_13

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  • DOI: https://doi.org/10.1007/978-3-642-85036-3_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85038-7

  • Online ISBN: 978-3-642-85036-3

  • eBook Packages: Springer Book Archive

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