Treatment of Oropharynx Carcinomas: Experience at the Institut Gustave-Roussy
Radiotheraphy (RT) alone is he preffered treatment of oropharynx carcinomas T1, T2, N0 and N1 at te Institut Gustave-Roussy (IGR). More advanced or ulcerative tumours are treated with surgery combined with RT. For this type of tumor, induction chemotherapy (CT) before RT or surgery was recently used in our institute. COmbined use of rediosensitizer and RT was also carried out recently in a European trial. For more advanced tumors, combined chemoradiotheraphy and hyperfractionated schedule of RT were used in other phase II trials. Part of the experience with these forms of treatment is reported here.
KeywordsLocal Control Induction Chemotherapy Palpable Node Nodal Response Oropharynx Cancer
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- Bourhis J, Wilson GD, Janot F, Chavaudra N, Leridant AM, Wibault P, Girinsky T, Luboinski B, Eschwege F, Malaise EP (1991) Mesure de la cinétique de proliféra-tion in vivo des cancers de 1’oropharynx par incorporation de bromodésoxyruridine et cytométrie de flux. Bull Cancer 78: 1045–1051PubMedGoogle Scholar
- Lartigau E (1992) Oxygenation of head and neck tumors. Radiation Research Society, 40th annual meeting, workshop geographic physiology of tumors. Salt Lake CityGoogle Scholar
- Lusinchi A, Eskandari J, Son Y, Gerbaulet A, Haie C, Mamelle G, Eschwege F, Chassagne D (1989a) External irradiation plus curietherapy boost in 108 base of tongue carcinoma. Int J Radiat Oncol Biol Phys 99: 1257–1259Google Scholar