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Nocardiosis, Lung

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Nonhuman Primates

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

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Abstract

Nocardial infection of the nonhuman primate lung is most often characterized by multinodular to diffuse, red to gray-white areas of consolidation in affected lobes (Sakakibara et al. 1984; McClure et al. 1976; Al-Doory et al. 1969; Jonas and Wyand 1966) (Fig. 113). Small abscesses with a purulent center (Jonas and Wyand 1966, Liebenberg and Giddens 1985) and larger cavitary lesions containing purulent exudate (Jonas and Wyand 1966) have also been described within the lungs of affected nonhuman primates. Although the lung has been the most frequently reported site of infection of nonhuman primates, firm consolidated nodules and abscesses have also been described in the peritoneum, liver, kidney, brain and subcutis (Table 8).

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References

  • Ajello L, Walker WW, Dungworth DL, Brumfield GL (1961) Isolation of Nocardia brasiliensis from a cat with a review of its prevalence and geographic distribution. J Am Vet Med Assoc 138:370–376

    CAS  Google Scholar 

  • Al-Doory Y, Pinkerton ME, Vice TE, Hutchinson V (1969) Pulmonary nocardiosis in a vervet monkey. J Am Vet Med Assoc 155:1179–1180

    PubMed  CAS  Google Scholar 

  • Beaman BL (1979) Interaction of Nocardia asteroides at different phases of growth within vitro-maintained macrophages obtained from the lungs of normal and immunized rabbits. Infect Immun 26:355–361

    PubMed  CAS  Google Scholar 

  • Beaman BL, Sugar AM (1983) Nocardia in naturally acquired and experimental infections in animals. J Hyg 91:393–419

    Article  CAS  Google Scholar 

  • Beaman BL, Burnside J, Edwards B, Causey W (1976) Nocardial infections in the United States, 1972–1974. J Infect Dis 134:286–289

    Article  PubMed  CAS  Google Scholar 

  • Beaman BL, Goldstein E, Gershwin ME, Maslan S, Lippert W (1978) Lung response to congenitally athymic (nude), heterozygous, and Swiss Webster mice to aerogenic and intranasal infection by Nocardia asteroides. Infect Immun 22:867–877

    PubMed  CAS  Google Scholar 

  • Boncyk LH, McCullough B, Grotts DD, Kalter SS (1975) Localized nocardiosis due to Nocardia caviae in a baboon (Papio cynocephalus). Lab Anim Sci 25:88–91

    PubMed  CAS  Google Scholar 

  • Carlton WW, Hunt RD (1978) Bacterial diseases. In: Benirschke K, Garner FM, Jones TC (eds) Pathology of laboratory animals. Springer, Berlin Heidelberg New York, pp 1429–1432

    Google Scholar 

  • Cole JR, Holzinger EA (1972) Nocardia asteroides associated with swine abortion. Vet Med/Small Anim Clin 67:496–498

    Google Scholar 

  • Conde C, Mancilla R, Fresan M, Ortiz-Ortiz L (1983) Immunoglobulin and complement in tissues of mice infected with Nocardia brasiliensis. Infect Immun 40: 1218–1222

    PubMed  CAS  Google Scholar 

  • Confer AW, Cox HU, Kleinpeter CC, MacWilliams PS, Hawk WC (1981) Disseminated nocardiosis in an Arabian foal. J Am Vet Med Assoc 179:481–484

    PubMed  CAS  Google Scholar 

  • Cooper JE (1973) Post-mortem findings in east African birds of prey. J Wildl Dis 9:368–375

    PubMed  CAS  Google Scholar 

  • Davis-Scibienski C, Beaman BL (1980a) Interaction of Nocardia asteroides with rabbit alveolar macrophages: association of virulence, viability, ultrastructural damage, and phagosome-lysosome fusion. Infect Immun 28: 610–619

    PubMed  CAS  Google Scholar 

  • Davis-Scibienski C, Beaman BL (1980b) Interaction of alveolar macrophages with Nocardia asteroides: immunologic enhancement of phagocytosis, phagosome-lysosome fusion and microbiocidal activity. Infect Immun 30:578–587

    PubMed  CAS  Google Scholar 

  • Deem RL, Doughty FA, Beaman BL (1983) Immunologically specific direct T lymphocyte killing of Nocardia asteroides. J Immunol 130:2401–2406

    PubMed  CAS  Google Scholar 

  • Ellwood DC (1973) Pulmonary nocardiosis in a goat in Malawi. Br Vet J 129:iv–vii

    PubMed  CAS  Google Scholar 

  • El Sanousi SM, Salih MAM, Mousa MT, Tag El Din MH, Ali SAM (1979) Further studies on the properties of the aetiology of bovine farcy isolated from Sudanese cattle. Rev Elev Med Vet Pays Trop 32:135–141

    PubMed  Google Scholar 

  • Gordon MA (1985) Aerobic pathogenic Actinomycetaceae. In: Lennette EH, Balows A, Hausler WJ Jr, Shadomy HJ (eds) Manual of clinical microbiology. American Society for Microbiology, Washington DC, pp 249–258

    Google Scholar 

  • Jonas AM, Wyand DS (1966) Pulmonary nocardiosis in the rhesus monkey. Importance of differentiation from tuberculosis. Pathol Vet 3:588–600

    Article  PubMed  CAS  Google Scholar 

  • Jungerman PF, Schwartzman RM (1972) Nocardiosis. In: Jungerman PF, Schwartzman RM (eds) Veterinary medical mycology. Lea and Febiger, Philadelphia, pp 171–183

    Google Scholar 

  • Kessler MJ, Brown RJ (1981) Mycetomas in a squirrel monkey (Saimiri sciureus). J Zoo Anim Med 12:91–93

    Article  Google Scholar 

  • Lechevalier HA (1977) Report on the cooperative study of the generic assignment of strains labeled Nocardia farcinica. Actinomycetes 12:15–23

    Google Scholar 

  • Liebenberg SP, Giddens WE Jr (1985) Disseminated nocardiosis in three macaque monkeys. Lab Anim Sci 35:162–166

    PubMed  CAS  Google Scholar 

  • Mahajan VM, Padhy SC, Dayal Y, Bhatia IM, Ratnaker KS (1977) Experimental pulmonary nocardiosis in monkeys. Sabouraudia 15:47–50

    Article  PubMed  CAS  Google Scholar 

  • McClure HM, Chang J, Kaplan W, Brown JM (1976) Pulmonary nocardiosis in an orangutan. J Am Vet Med Assoc 169:943–945

    PubMed  CAS  Google Scholar 

  • Nocard E (1888) Note sur la maladie des boeufs de la Guadaloupe connue sous le nom de farcin. Ann Inst Pasteur 2:293–302

    Google Scholar 

  • Robertson SA, Stoddart ME, Evans RJ, Gaskell CJ, Gibbs C (1983) Thoracic empyema in the dog; a report of twenty-two cases. J Small Anim Pract 24:103–119

    Article  Google Scholar 

  • Sakakibara I, Sugimoto Y, Minato H, Takasaka M, Honjo S (1984) Spontaneous nocardiosis with brain abscess caused by Nocardia asteroides in a cynomolgus monkey. J Med Primatol 13:89–95

    PubMed  CAS  Google Scholar 

  • Shigidi MTA, Mirghani T, Musa MT (1980) Characterization of Nocardia farcinica isolated from cattle with bovine farcy. Res Vet Sci 28:207–211

    PubMed  CAS  Google Scholar 

  • Snieszko SF, Bullock GL, Dunbar CE, Pettijohn LL (1964) Nocardial infection in hatchery-reared fingerling rainbow trout (Salmo gairdneri). J Bacteriol 88:1809–1810

    PubMed  CAS  Google Scholar 

  • Sweeney JC, Migaki G, Vainik PM, Conklin RH (1976) Systemic mycoses in marine mammals. J Am Vet Med Assoc 169:946–948

    PubMed  CAS  Google Scholar 

  • von Lichtenberg F (1989) Infectious disease. In: Cotran RS, Kumar V, Robbins SL (eds) Robbins pathologic basis of disease. Saunders, Philadelphia, p 383

    Google Scholar 

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Authors
  1. Sherry A. Klumpp
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  2. Harold M. McClure
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Editor information

Editors and Affiliations

  1. Harvard Medical School, ILSI Research Foundation, 1126 Sixteenth Street, N. W., Washington, DC, 20036, USA

    Thomas Carlyle Jones D. V.M., D.Sc. (Professor of Comparative Pathology, Emeritus) (Professor of Comparative Pathology, Emeritus)

  2. Institut für Experimentelle Pathologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Strasse 8, 30625, Hannover, Federal Republic of Germany

    Ulrich Mohr M. D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

  3. New England Regional Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA, 01772, USA

    Ronald Duncan Hunt D. V.M. (Professor of Comparative Pathology) (Professor of Comparative Pathology)

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© 1993 Springer-Verlag Berlin Heidelberg

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Klumpp, S.A., McClure, H.M. (1993). Nocardiosis, Lung. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Nonhuman Primates. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84924-4_22

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  • DOI: https://doi.org/10.1007/978-3-642-84924-4_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84926-8

  • Online ISBN: 978-3-642-84924-4

  • eBook Packages: Springer Book Archive

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