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Environmental Risk Factors for Skin Cancer

  • F. Urbach
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 128)

Abstract

That chronic exposure to environmental agents can lead to the development of skin cancer in humans has been known for more than 200 years, since Percival Pott described scrotal cancer in chimney sweeps in 1775. Today, the evidence is convincing that the vast majority of skin cancers are due to chronic repeated exposure to solar ultraviolet (UV) radiation. Skin cancers are most prevalent on light complexioned, easily sunburning individuals, and in those who receive the most solar exposure, whether because of occupational or deliberate social reasons. Furthermore, non-melanoma skin cancers occur primarily on sunlight-exposed sites. The recent significant decrease in stratospheric ozone, which increases transmitted short-wavelength UV radiation, has the potential of significantly increasing skin cancer incidence in the future. The dose-response relationships and epidemiologic features of UV-induced skin cancers will be discussed here. Other environmental causes for skin cancer development are exposure to chemicals (polycyclic hydrocarbons derived from the incomplete combustion or distillation of coal or petroleum; inorganic arsenic and photosensitizing agents such as psoralens). In the past, occupational or therapeutic exposure to ionizing radiation has caused skin cancer. Finally, there is some evidence that intense, chronic infrared radiation can enhance the development of skin cancer.

Keywords

Skin Cancer Natl Cancer Inst Environmental Risk Factor Stratospheric Ozone Total Ozone Column 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1993

Authors and Affiliations

  • F. Urbach
    • 1
  1. 1.Temple Medical PracticesFort WashingtonUSA

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