Abstract
Steroid hormones bind to their corresponding receptors in the cytoplasm of responsive cells and this complex is translocated to the nucleus where the hormone-receptor-complex binds to specific DNA sequences located in the regulatory regions of the target gene. These specific DNA sequences are referred to as hormone responsive elements (HRE) and act as enhancer elements such that when the receptor complex binds, transcription is induced. In the absence of ligand the hormone receptor is maintained in an inactive form by association with other cellular proteins.
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References
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© 1993 Springer-Verlag Berlin Heidelberg
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Slater, E.P., Beato, M. (1993). Interaction of Steroid Hormone Receptors with DNA. In: Steinmetz, A., Schneider, J., Kaffarnik, H. (eds) Hormones in Lipoprotein Metabolism. Recent Developments in Lipid and Lipoprotein Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84855-1_1
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DOI: https://doi.org/10.1007/978-3-642-84855-1_1
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