Salvage Treatment After Local Breast Cancer Relapse
Local recurrence after mastectomy as primary treatment of breast cancer has been associated with poor prognosis. In a Swiss study analyzing prospectively the outcome of 225 local recurrences after mastectomy, Brunner et al.  observed in 1988 a somewhat better prognosis than generally published, partly as a consequence of a strict search for distant metastases at the time of treatment of the recurrence and as an ineligibility criterion for this study. Under these conditions, disease-free survival was 47% at 5 years. The strongest factors in the multivariate analysis determining disease-free survival were the initial axillary lymph node status and the time elapsed between mastectomy and appearance of the local recurrence.
KeywordsLocal Recurrence Local Failure Musculocutaneous Flap Extensive Intraductal Component Early Stage Breast Carcinoma
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