Molecular Cloning of Nurse Shark cDNAs with High Sequence Similarity to Nucleoside Diphosphate Kinase Genes

  • Masanori Kasahara
  • Camilo Canel
  • E. Churchill McKinney
  • Martin F. Flajnik
Part of the NATO ASI Series book series (volume 59)


In the course of our study aimed at isolating class II genes of the major histocompatibility complex from primitive vertebrates, nurse shark cDNA clones assumed to encode a nucleoside diphosphate kinase were isolated. The deduced amino acid sequence of the putative nurse shark nucleoside diphosphate kinase protein has two cysteinyl residues approximately 60 amino acid residues apart from each other. Weak amino acid sequence similarity was found between the putative nurse shark nucleoside diphosphate kinase and C1-SET members of the immunoglobulin superfamily.


Major Histocompatibility Complex Class Amino Acid Sequence Identity Dictyostelium Discoideum Nucleoside Diphosphate Kinase Nurse Shark 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • Masanori Kasahara
    • 1
  • Camilo Canel
    • 1
  • E. Churchill McKinney
    • 1
  • Martin F. Flajnik
    • 1
  1. 1.Department of Microbiology and ImmunologyUniversity of Miami School of MedicineMiamiUSA

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