Interpreting MHC Disequilibrium

  • William Klitz
  • Glenys Thomson
Conference paper
Part of the NATO ASI Series book series (volume 59)


The record of non-random association of alleles between tightly linked loci in a population contains a wealth of information on the recent evolutionary past. Methods for the analysis of disequilibrium are presented and exemplified with application to HLA data.


Single Haplotype Gametic Disequilibrium DQA3 Allele Disequilibrium Measure Multi Allelic Locus 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • William Klitz
    • 1
  • Glenys Thomson
    • 1
  1. 1.Department of Integrative BiologyUniversity of CaliforniaBerkeleyUSA

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