Skip to main content

Urate and Uric Acid Crystal Reactions Within the Kidney — Clinical and Experimental Studies

  • Conference paper
Urate Deposition in Man and its Clinical Consequences
  • 54 Accesses

Abstract

It is difficult to define the complications of gout because gout is not a single disease entity, and there will often be multiple factors contributing to the development of complications. Accordingly, it should not be expected that such complications will have a uniform pattern.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Batch JA, Riek RP, Gordon RB, Burke JR, Emmerson BT (1984) Renal failure in infancy due to over-production of urate. Aust NZ J Med 14: 852–854

    Article  CAS  Google Scholar 

  2. Emmerson BT (1973) Chronic lead nephropathy. Kidney Int 4: 1–5

    Article  PubMed  CAS  Google Scholar 

  3. Emmerson BT, Row PG (1975) An evaluation of the pathogenesis of the gouty kidney. Kidney Int 8: 65–71

    Article  PubMed  CAS  Google Scholar 

  4. Emmerson BT, Thompson L (1973) The spectrum of hypoxanthine-guanine phosphoribosyltransferase deficiency. Q J Med 42: 423–40

    PubMed  CAS  Google Scholar 

  5. Emmerson BT, Gordon RB, Johnson LA (1976) Urate kinetics in hypoxanthineguanine phosphoribosyltransferase deficiency: their significance for the understanding of gout. Q J Med 177: 49–61

    Google Scholar 

  6. Emmerson BT, Stride PJ, Williams G (1980) The clinical differentiation of primary gout from primary renal disease in patients with both gout and renal disease. Adv Exp Med Biol 122A: 9–13

    Google Scholar 

  7. Emmerson BT, Cross M, Osborne JM, Axelsen RA (1990) Reaction of MDCK cells to crystals of monosodium urate monohydrate and uric acid. Kidney Int 37: 36–43

    Article  PubMed  CAS  Google Scholar 

  8. Epstein FH, Pigeon G (1964) Experimental urate nephropathy: studies of the distribution of urate in renal tissue. Nephron 1: 144–157

    Article  PubMed  CAS  Google Scholar 

  9. Kanwar YS, Manaligod JR (1975) Leukemic urate nephropathy. Arch Pathol 99: 467–472

    PubMed  CAS  Google Scholar 

  10. Linnane JW, Burry AF, Emmerson BT (1981) Urate deposits in the renal medulla: prevalence and associations. Nephron 29: 216–222

    Article  PubMed  CAS  Google Scholar 

  11. Ostberg Y (1968) Renal urate deposits in chronic renal insufficiency. Acta Med Scand 183: 197–201

    Article  PubMed  CAS  Google Scholar 

  12. Seegmiller JE, Frazier PD (1966) Biochemical considerations of the renal damage of gout. Ann Rheum Dis 25: 668–672

    PubMed  CAS  Google Scholar 

  13. Verger D, Leroux-Robert C, Ganter P, Richet G (1967) Presence and role of gouty tophi in the renal medulla of patients with chronic uremia. Nephron 4: 356–370

    Article  PubMed  CAS  Google Scholar 

  14. Moro F, Ogg C, Cameron JS, Simmonds HA, Duley JA, McBride MB, Davies PM (1991) Familial juvenile gouty nephropathy with renal urate hypoexcretion preceding renal disease. Clin Nephrol (in press)

    Google Scholar 

  15. Cameron JS, Ogg CS, Moro F, Chantler C, Simmonds HA (1990) Precocious familial gout (letter). Lancet ii: 745

    Article  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer Verlag, Berlin Heidelberg

About this paper

Cite this paper

Emmerson, B.T. (1991). Urate and Uric Acid Crystal Reactions Within the Kidney — Clinical and Experimental Studies. In: Gresser, U., Zöllner, N. (eds) Urate Deposition in Man and its Clinical Consequences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84491-1_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-84491-1_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84493-5

  • Online ISBN: 978-3-642-84491-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics