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Cyclosporin A in der Dermatologie

  • Conference paper
Supplementum X, 41. Jahrgang 1990 Verhandlungen der Deutschen Dermatologischen Gesellschaft

Part of the book series: Der Hautarzt ((VDGDERMATOLOGIE,volume 36))

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Zusammenfassung

Die klassischen Immunsuppressiva Glukokortikosteroide und Azathioprin hemmen die Zellteilung aller Elemente des Immunsystems sowie die Produktion von Zytokinen. Das ist ein relativ breit gefächertes Spektrum von Wirkungen. Im Gegensatz dazu inhibiert Cyclosporin A (CsA) selektiv die adaptative Immunantwort, vorrangig den T-Zellschenkel, bis zu einem gewissen Grade aber auch davon unabhängig den B-Zellschenkel. Daneben verursacht es dosisabhängig eine Reihe von nicht-immunologischen Nebenwirkungen, deren genaue Kenntnis Voraussetzung für den therapeutischen Einsatz dieses außerordentlich interessanten Medikaments ist.

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Literatur

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Author information

Authors and Affiliations

  1. Klinik für Dermatologie und Allergologie, Stenglinstraße 1, D-8900, Augsburg, Germany

    Prof. Dr. Prof. h.c. Bernd-Rüdiger Balda

Authors
  1. Prof. Dr. Prof. h.c. Bernd-Rüdiger Balda
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Editors and Affiliations

  1. Hautklinik Linden, Medizinische Hochschule Hannover, Ricklinger Straße 5, D-3000, Hannover 91, Germany

    Sandor Marghescu , Dietrich Lubach  & Christine Neumann ,  & 

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© 1991 Springer-Verlag Berlin Heidelberg

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Balda, BR. (1991). Cyclosporin A in der Dermatologie. In: Marghescu, S., Lubach, D., Neumann, C. (eds) Supplementum X, 41. Jahrgang 1990 Verhandlungen der Deutschen Dermatologischen Gesellschaft. Der Hautarzt, vol 36. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84370-9_42

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  • DOI: https://doi.org/10.1007/978-3-642-84370-9_42

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-53468-6

  • Online ISBN: 978-3-642-84370-9

  • eBook Packages: Springer Book Archive

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