Abstract
Lysosomes are terminal degradative compartments involved in the degradation of extracellular and intracellular macromolecules (Kornfeld and Mellman, 1989). Degradation is performed by a large variety of soluble acidic hydrolases, many of which are well characterized. The functions of the lysosomal membrane proteins are less well understood, but they are believed to be involved in such diverse roles as, the maintenance of the membrane structure, the transport of ions and small molecules through the membrane, and in the movement and fusion of lysosomes with other organelles. Only recently, the first membrane proteins have been characterized (Pohlmann et al., 1988; Chen et al., 1988; Howe et al., 1988; Viitala et al., 1988; Fukuda et al., 1988; Noguchi et al., 1989; Cha et al., 1990).
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© 1992 Springer-Verlag Berlin Heidelberg
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Seguí-Real, B., Vega, M.A., Barriocanal, J.G., Yuan, L., Alcalde, J., Sandoval, I.V. (1992). Biochemical Characterization, Structure and Transport of Lysosomal Integral Membrane Proteins. In: Courtoy, P.J. (eds) Endocytosis. NATO ASI Series, vol 62. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84295-5_27
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DOI: https://doi.org/10.1007/978-3-642-84295-5_27
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