A Comparison of Characteristics in 33 Japanese and 83 American Patients with Prader-Willi Syndrome
Prader-Willi Syndrome (PWS) was identified in 1956 (Prader et al, 1956) and has been reported to occur in all racial groups (Golden et al, 1984; Ikeda et al, 1973). Clinical diagnosis is based on the presence of hypotonia in infancy, obesity occurring after age 2, hypogonadism (which is evidenced by cryptorchidism in males), and mild mental retardation. Additional findings include skin picking, speech problems, behavior problems, and short stature.
KeywordsObesity Carbohydrate Hypogonadism Cryptorchidism
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