Skip to main content
SpringerLink
Log in

Detection of Alkaloids in Environmental Tobacco Smoke

  • Chapter
Alkaloids

Part of the book series: Modern Methods of Plant Analysis ((MOLMETHPLANT,volume 15))

Abstract

Tobacco is one of the most complex plants known, drawing its complexity from both genetic and environmental sources. Of the more than 60 genetic species of plants belonging to the genus Nicotiana, only two (N. tabacum and N. rustica) are widely cultivated for use as tobacco. N. tabacum, the tobacco of commerce, is a hybrid plant capable of a high degree of variability, as evidenced by the different major commercial types (flue-cured, burley, Maryland, and Oriental) and the numerous agronomic varieties within each type (Wolf 1967). Each of these types, in addition to others, is currently used in the manufacture of cigarettes, cigars, and pipe tobaccos.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • AOAC (1990) Nicotine in environmental tobacco smoke: gas chromatographic method. In: Official methods of analysis, 15th edn, 1st suppl. Association of Official Analytical Chemists, Arlington, Virginia, method no 990.01

    Google Scholar 

  • ASTM (1990) Standard test method for nicotine in indoor air. In: 1990 Annual book of ASTM standards. American Society for Testing and Materials, Philadelphia, Pennsylvania, vol 11.03, method no D 5075–90, pp 427–433

    Google Scholar 

  • Benner CL, Bayona JM, Caka FM, Tang H, Lewis L, Crawford J, Lamb JD, Lee ML, Lewis EA, Eatough DJ (1989) Chemical composition of environmental tobacco smoke. 2. Particulate-phase compounds. Environ Sci Technol 23:688–699

    Article  CAS  Google Scholar 

  • Caka FM, Eatough DJ, Lewis EA, Tang H, Hammond SK, Leaderer BP, Spengler JD, Fasano A, McCarthy J, Ogden MW, Lewtas J (1990) An intercomparison of sampling techniques for nicotine in indoor environments. Environ Sci Technol 24:1196–1203

    Article  CAS  Google Scholar 

  • Castro A, Monji N (1986) Dietary nicotine and its significance in studies on tobacco smoking. Biochem Arch 2:91–97

    CAS  Google Scholar 

  • Davis RA, Stiles MF, deBethizy JD, Reynolds JH (1991) Dietary nicotine: a source of urinary cotinine. Food Chem Toxicol 29:821–827

    Article  PubMed  CAS  Google Scholar 

  • deBethizy JD, Bates LE, Davis RA, Heavner DL, Nelson PR, Walker JC, Robinson JH (1989) Nicotine absorption in humans following exposure to environmental tobacco smoke generated from different types of cigarettes. In: Bieva CJ, Courtois Y, Govaerts M (eds) Present and future of indoor air quality. Elsevier, Amsterdam, pp 269–276

    Google Scholar 

  • Dube MF, Green CR (1982) Methods of collection of smoke for analytical purposes. Recent Adv Tob Sci 8:42–102

    Google Scholar 

  • Eatough DJ, Benner C, Mooney RL, Bartholomew D, Steiner DS, Hansen LD, Lamb JD, Lewis EA (1986) Gas and particle phase nicotine in environmental tobacco smoke. Proc 79th Annual Meet Air Pollution Control Assoc. Air Pollution Control Assoc, Pittsburgh, paper 86–68.5

    Google Scholar 

  • Eatough DJ, Benner CL, Bayona JM, Caka FM, Tang H, Lewis L, Lamb JD, Lee ML, Lewis EA, Hansen LD (1987) Sampling for gas phase nicotine in environmental tobacco smoke with a diffusion denuder and a passive sampler. Proc 1987 EPA/ APCA Int Symp Measurement of toxic and related air pollutants. Air Pollution Control Assoc, Pittsburgh, pp 132–139

    Google Scholar 

  • Eatough DJ, Wooley K, Tang H, Lewis EA, Hansen LD, Eatough NL, Ogden MW (1988) Sampling gaseous compounds in environmental tobacco smoke. Proc 1988 EPA/APCA Int Symp Measurement of toxic and related air pollutants. Air Pollution Control Assoc, Pittsburgh, pp 739–749

    Google Scholar 

  • Eatough DJ, Benner CL, Bayona JM, Richards G, Lamb JD, Lee ML, Lewis EA, Hansen LD (1989a) Chemical composition of environmental tobacco smoke. 1. Gasphase acids and bases. Environ Sci Technol 23:679–687

    Article  CAS  Google Scholar 

  • Eatough DJ, Benner CL, Tang H, Landon V, Richards G, Caka FM, Crawford J, Lewis EA, Hansen LD (1989b) The chemical composition of environmental tobacco smoke III. Identification of conservative tracers of environmental tobacco smoke. Environ Int 15:19–28

    Article  CAS  Google Scholar 

  • Eatough DJ, Hansen LD, Lewis EA (1990) The chemical characterization of environmental tobacco smoke. Environ Technol 11:1071–1085

    Article  CAS  Google Scholar 

  • Eudy LW, Thome FA, Heavner DL, Green CR, Ingebrethsen BJ (1986) Studies on the vapor-particulate phase distribution of environmental nicotine by selective trapping and detection methods. Proc 79th Annual Meet Air Pollution Control Assoc, Pittsburgh, paper 86–38.7

    Google Scholar 

  • Guerin MR, Jenkins RA, Tomkins BA (1992) The chemistry of environmental tobacco smoke: composition and measurement. Lewis, Chelsea, Michigan

    Google Scholar 

  • Hammond SK, Leaderer BP (1987) A diffusion monitor to measure exposure to passive smoking. Environ Sci Technol 21:494–497

    Article  CAS  Google Scholar 

  • Hammond SK, Leaderer BP, Roche AC, Schenker M (1987) Collection and analysis of nicotine as a marker for environmental tobacco smoke. Atmos Environ 21:457– 462

    Article  CAS  Google Scholar 

  • Heavner DL, Ogden MW, Nelson PR (1992) Multisorbent thermal desorption gas chromatography/mass selective detection method for the determination of target volatile organic compounds in indoor air. Environ Sci Technol 26:1737–1746

    Article  CAS  Google Scholar 

  • Kuhn H (1965) Tobacco alkaloids and their pyrolysis products in the smoke. In: von Euler US (ed) Tobacco alkaloids and related compounds: proc fourth int symp held at the Wenner-Gren center, vol 4. Stockholm, February 1964. Macmillan, New York, pp 37–51

    Google Scholar 

  • Leete E (1983) Biosynthesis and metabolism of the tobacco alkaloids. In: Pelletier SW (ed) Alkaloids: chemical and biological perspectives, vol 1. John Wiley, New York, pp 85–152

    Google Scholar 

  • Nelson PR (1991) Internal standard correction of results obtained by atmospheric pressure chemical ionization mass spectrometry. J Am Soc Mass Spectrom 2: 427–431

    Article  CAS  Google Scholar 

  • Nelson PR, Ogden MW (1990) Measurement of ethenylpyridine in environmental tobacco smoke. In: Proc 38th ASMS Conf on Mass spectrometry and allied topics. American Society for Mass Spectrometry, East Lansing, Michigan, pp 677–678

    Google Scholar 

  • Nelson PR, Heavner DL, Collie BB (1989) Characterization of the environmental tobacco smoke generated by different cigarettes. In: Bieva CJ, Courtois Y, Govaerts M (eds) Present and future of indoor air quality. Elsevier, Amsterdam, pp 277–282

    Google Scholar 

  • Nelson PR, Heavner DL, Oldaker GB III (1990) Problems with the use of nicotine as a predictive environmental tobacco smoker marker. Proc 1990 EPA/A&WMA Int Symp Measurement of toxic and related air pollutants. Air and Waste Management Assoc, Pittsburgh, pp 550–555

    Google Scholar 

  • Nelson PR, deBethizy JD, Davis RA, Oldaker GB III (1991) Where there’s smoke... ? Biases in the use of nicotine and cotinine as environmental tobacco smoke biomarkers. Proc 1991 EPA/A&WMA Int Symp Measurement of toxic and related air pollutants. Air and Waste Management Assoc, Pittsburgh, pp 449–454

    Google Scholar 

  • Ogden MW (1989) Gas chromatographic determination of nicotine in environmental tobacco smoke: collaborative study. J Assoc Off Anal Chem 72:1002–1006

    PubMed  CAS  Google Scholar 

  • Ogden MW (1991) Use of capillary chromatography in the analysis of environmental tobacco smoke. In: Jennings W, Nikelly JG (eds) Capillary chromatography - the applications. Hüthig, Heidelberg, pp 67–82

    Google Scholar 

  • Ogden MW (1992) Equivalency of gas chromatographic conditions in determination of nicotine in environmental tobacco smoke: minicollaborative study. J Assoc Off Anal Chem 75:729–733

    CAS  Google Scholar 

  • Ogden MW, Maiolo KC (1989) Collection and determination of solanesol as a tracer of environmental tobacco smoke in indoor air. Environ Sci Technol 23:1148–1154

    Article  CAS  Google Scholar 

  • Ogden MW, Maiolo KC (1992) Comparative evaluation of diffusive and active sampling systems for determining airborne nicotine and 3-ethenylpyridine. Environ Sci Technol 26:1226–1234

    Article  CAS  Google Scholar 

  • Ogden MW, Davis RA, Maiolo KC, Stiles MF, Heavner DL, Hege RB, Morgan WT (1993) Multiple measures of personal ETS exposure in a population-based survey of nonsmoking women in Columbus, Ohio. Proc 6th Int Conf on Indoor air quality and climate. Indoor Air ’93, Helsinki, vol 1, pp 523–528

    Google Scholar 

  • Ogden MW, Eudy LW, Heavner DL, Conrad FW Jr, Green CR (1989a) Improved gas chromatographic determination of nicotine in environmental tobacco smoke. Analyst 114:1005–1008

    Article  PubMed  CAS  Google Scholar 

  • Ogden MW, Nystrom CW, Oldaker GB III, Conrad FW Jr (1989b) Evaluation of a personal passive sampling device for determining exposure to nicotine in environmental tobacco smoke. Proc 1989 EPA/A&WMA Int Symp Measurement of toxic and related air pollutants. Air and Waste Management Assoc, Pittsburgh, pp 552– 558

    Google Scholar 

  • Pailer M (1965) Chemistry of nicotine and related alkaloids (including biosynthetic aspects). In: von Euler US (ed) Tobacco alkaloids and related compounds: proc fourth int symp held at the Wenner-Gren center, vol 4. Stockholm, February 1964. Macmillan, New York, pp 15–36

    Google Scholar 

  • Pelletier SW (1983) The nature and definition of an alkaloid. In: Pelletier SW (ed) Alkaloids: chemical and biological perspectives, vol 1. John Wiley, New York, pp 1–31

    Google Scholar 

  • Proctor CJ, Warren ND, Bevan MAJ (1989) Measurements of environmental tobacco smoke in an air conditioned office building. Environ Tech Lett 10:1003–1018

    Article  CAS  Google Scholar 

  • SCIEX (1989) The API book. SCIEX division of MDS, Thornhill, Ontario

    Google Scholar 

  • Sheen S (1988) Detection of nicotine in foods and plant materials. J Food Sci 53:1572– 1573

    Article  CAS  Google Scholar 

  • Stedman RL (1968) The chemical composition of tobacco and tobacco smoke. Chem Rev 68(2): 153–207

    Article  PubMed  CAS  Google Scholar 

  • Sunner J, Ikonomou MG, Kebarle P (1988a) Sensitivity enhancements obtained at high temperatures in atmospheric pressure ionization mass spectrometry. Anal Chem 60:1308–1313

    Article  CAS  Google Scholar 

  • Sunner J, Nicol G, Kebarle P (1988b) Factors determining relative sensitivity of analytes in positive ion mode atmospheric pressure ionization mass spectrometry. Anal Chem 60:1300–1307

    Article  CAS  Google Scholar 

  • Thome FA, Heavner DL, Ingebrethsen BJ, Eudy LW, Green CR (1986) Environmental tobacco smoke monitoring with an atmospheric pressure chemical ionization mass spectrometer/mass spectrometer coupled to a test chamber. Proc 79th Annual Meet Air Pollution Control Assoc. Air Pollution Control Assoc, Pittsburgh, paper 86–37.6

    Google Scholar 

  • Thompson CV, Jenkins RA, Higgins CE (1989) A thermal desorption method for the determination of nicotine in indoor environments. Environ Sci Technol 23:429–435

    Article  CAS  Google Scholar 

  • Thomson BA, Davidson WR, Lovett AM (1980) Applications of a versatile technique for trace analysis: atmospheric pressure negative chemical ionization. Environ Health Perspect 36:77–84

    Article  PubMed  CAS  Google Scholar 

  • US EPA (1990) Determination of nicotine in indoor air using XAD-4 sorbent tubes. In: Compendium of methods for the determination of air pollutants in indoor air. US Environmental Protection Agency, Research Triangle Park, North Carolina, EPA/ 600/S4–90/010, chap 2, method no IP-2A

    Google Scholar 

  • Wolf FA (1967) Tobacco production and processing. In: Wynder EL, Hoffmann D (eds) Tobacco and tobacco smoke. Academic Press, New York, pp 5–45

    Google Scholar 

  • Wynder EL, Hoffmann D (1967) Certain constituents of tobacco products. In: Wynder EL, Hoffmann D (eds) Tobacco and tobacco smoke. Academic Press, New York, pp 317–501

    Google Scholar 

Download references

Authors
  1. M. W. Ogden
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. R. Nelson
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Goldberglein 7, D-91056, Erlangen, Germany

    Hans Ferdinand Linskens

  2. Department of Horticulture, Viticulture and Oenology Waite Agricultural Research Institute, University of Adelaide, Glen Osmond, S.A., 5064, Australia

    John F. Jackson

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Ogden, M.W., Nelson, P.R. (1994). Detection of Alkaloids in Environmental Tobacco Smoke. In: Linskens, H.F., Jackson, J.F. (eds) Alkaloids. Modern Methods of Plant Analysis, vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84226-9_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-84226-9_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84228-3

  • Online ISBN: 978-3-642-84226-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation