The Thymus pp 35-55 | Cite as

Diagnostic Imaging of the Normal Thymus

  • E. Willich
  • E. Walter
  • W. R. Webb
  • G. de Geer
Part of the Medical Radiology book series (MEDRAD)

Abstract

The thymus is by far the most frequent cause of an enlarged mediastinal shadow in newborns and infants. It varies enormously in size and shape (Fig. 5.1) and in general is well differentiated on chest radiographs up to the 2nd year of age or beyond.

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References

  1. Amann L (1962) Der Thymus beim Säugling und Kleinkind aus heutiger Sicht. Pädiatr Prax 1: 385Google Scholar
  2. Amour TES, Siegel MJ, Glazer HS, Nadel SN (1987) CT appearance of the normal and abnormal thymus in childhood. J Comput Assist Tomogr 11: 645CrossRefGoogle Scholar
  3. Baron RL, Lee JKT, Sagel SS, Peterson RR (1982) Computed tomography of the normal thymus. Radiology 142: 121PubMedGoogle Scholar
  4. Batra P, Hermann C Jr, Mulder D (1987) Mediastinal imaging in myasthenia gravis: correlation of chest radiography, CT, MR, and surgical findings. AJR 148: 515PubMedGoogle Scholar
  5. Bode U, Scheidt W (1988) Change of thymic size during and following cytotoxic therapy in young patients. Pediatr Radiol 18: 20PubMedCrossRefGoogle Scholar
  6. de Geer G, Webb WR, Gamsu G (1986) Normal thymus: assessment with MR and CT. Radiology 158: 313PubMedGoogle Scholar
  7. Dixon AK, Hilton CJ, Williams GT (1981) Computed tomography and histological correlation of the thymic remnant. Clin Radiol 32: 255PubMedCrossRefGoogle Scholar
  8. Ebel K-D (1980) Zur Röntgendiagnostik des Thymus im Kindesalter. Radiologe 20:379PubMedGoogle Scholar
  9. Francis IR, Glazer GM, Bookstein FL, Gross BH (1985) The thymus: reexamination of age-related changes in size and shape. AJR 145: 249PubMedGoogle Scholar
  10. Gefferth K (1955) Thymus? Mediastinalpleuritis? Ein Beitrag zum diagnostischen Wert der interlobären Haarlinie. Fortschr Röntgenol 82:462CrossRefGoogle Scholar
  11. Gewolb JH, Lebowitz RL, Taeusch HW (1979) Thymus size and its relationship to the respiratory distress syndrome. J Pediatr 95:108PubMedCrossRefGoogle Scholar
  12. Goske Rudick M, Wood BP (1980) The use of ultrasound in the diagnosis of a large thymic cyst. Pediatr Radiol 10:113CrossRefGoogle Scholar
  13. Haller JO, Schneider M, Kassner EG, Friedman AP, Waldroup LD (1980) Sonographic evaluation of the chest in infants and children. AJR 134:1019PubMedGoogle Scholar
  14. Heiberg E, Wolverson MK, Sundaram M, Nouri S (1982) Normal thymus: CT characteristics in subjects under age 20. AJR 138: 491PubMedGoogle Scholar
  15. Helzel M (1985) Sonographische Topographie des oberen vorderen Mediastinums. Ultraschall Med 6:101PubMedCrossRefGoogle Scholar
  16. Hoeffel JC, Fourchy E, Marchai AL, Pernot C(1984) Aspects radiologiques de l’hypotrophic thymique chez le nourrisson. Radiologie J CEPUR 4:209Google Scholar
  17. Kemp FH (1950) Factors influencing the mediastinal shadow in young children. Br J Radiol 23: 703PubMedCrossRefGoogle Scholar
  18. Kim Han B, Babcock DS, Oestreich AE (1989) Normal thymus in infancy: sonographic characteristics. Radiology 170: 471Google Scholar
  19. Lack EE (1981) Thymic hyperplasia with massive enlargement. J Thorac Cardiovasc Surg 81:741PubMedGoogle Scholar
  20. Lanning R, Heikkinen E (1980) Thymus simulating left upper lobe atelectasis. Pediatr Radiol 9:177PubMedCrossRefGoogle Scholar
  21. Lemaitre L, Marconi V, Avni F, Remy J (1987) The sonographic evaluation of normal thymus in infants and children. Eur J Radiol 7:130PubMedGoogle Scholar
  22. Mangelmann M (1981) Die Thymusreaktion im Neugeborenenalter. Klinisch-radiologische Untersuchung bei Frühgeborenen mit und ohne Steroidmedikation der Mütter. Thesis, HeidelbergGoogle Scholar
  23. Miller JH (ed) (1985) Imaging in pediatric oncology. Williams and Wilkins, Baltimore, p 152Google Scholar
  24. Moore AV, Korobkin M, Olanow W, Heaston DK, Ram PC, Dunnick NR, Silverman PM (1983) Age-related changes in the thymus gland: CT-pathologic correlation. AJR 141: 241PubMedGoogle Scholar
  25. Moseley JE (1960) Loculated pneumomediastinum in the newborn, a thymic spinnaker sail sign. Radiology 75: 778Google Scholar
  26. Mulvey RB (1963) The thymic wave sign. Radiology 81:834PubMedGoogle Scholar
  27. Oliva L (1973) Erkrankungen des Mediastinums. In: Schinz HR, Baensch WE, Frommhold W, Glauner R, Uehlinger E, Wellauer J (eds) Lehrbuch der Röntgendiagnostik, vol IV/2, 6. Pleura, Mediastinum und Lunge. Thieme, StuttgartGoogle Scholar
  28. Otlani T (1958) Thymusvergrößerung bei Kindern. Monatsschr Kinderheilkd 106:143Google Scholar
  29. Parker LA, Gaisie G, Scatliff JH (1985) Computerized tomography and ultrasonic findings in massive thymic hyperplasia. Clin Pediatr (Phila) 24: 90CrossRefGoogle Scholar
  30. Reither M (1984) Thoraxsonographie im Kindesalter. Röntgenpraxis 10:375Google Scholar
  31. Salonen OLM, Kivisaari ML, Somer JK (1984) Computed tomography of the thymus of children under 10 years. Pediatr Radiol 14: 373PubMedCrossRefGoogle Scholar
  32. Schnell VY (1975) Probleme der Thymusdiagnostik bei atypischer Lage und seltenen Begleitumständen. Thesis, CologneGoogle Scholar
  33. Siegel MJ, Glazer HS, Wiener JI, Molina PL (1989) Normal and abnormal thymus in childhood: MR imaging. Radiology 172: 367PubMedGoogle Scholar
  34. Sone S, Higashihara T, Morimoto S et al. (1980) Normal anatomy of thymus and anterior mediastinum by pneumomediastinography. AJr 134: 81PubMedGoogle Scholar
  35. Steinmann GG (1986) Changes in human thymus during aging. In: Müller-Hermenlink HK (ed) Current topics in pathology. The human thymus. Histophysiology and pathology. Springer, Berlin Heidelberg New York, p 43Google Scholar
  36. Stern VN, Popow JA (1977) Der Einfluß des Thymus auf das Röntgenbild des Mediastinalschattens bei Kindern. Radiol Diagn (Berl) 18: 775Google Scholar
  37. Swischuk LE (1980) Radiology of the newborn and young infant, 2nd edn. Williams and Wilkins, Baltimore, p 27Google Scholar
  38. Tausend ME, Stern WZ (1965) Thymic pattern in the newborn. AJR 95:125Google Scholar
  39. von Lengerke HJ, Schmidt H (1988) Mediastinalsonographie im Kindesalter. Ergebnisse bei 310 Untersuchungen. Radiologe 28:460Google Scholar
  40. Walter E (1988) Erkrankungen und Tumoren des Thymuim Erwachsenenalter. In: Diethelm L, Heuck F, OlssonGoogle Scholar
  41. Weitzel D, Dinkel E, Dittrich M, Peters H (eds) (1984) Pädiatrische Ultraschalldiagnostik. Springer, Berlin Heidelberg New York, p 43CrossRefGoogle Scholar
  42. Wernecke K, Peters PR, Galanski M (1986) Mediastinal tumors: evaluation with suprasternal sonography. Radiology 159:405PubMedGoogle Scholar
  43. Willich E (1988) Bildgebende Diagnostik des Thymus vom Wachstums- bis ins Erwachsenenalter. In: Diethelm L, Heuck F, Olsson O, Strnad F, Vieten H, Zuppinger A (eds) Röntgendiagnostik der oberen Speise- und Atemwege und des Mediastinums. Springer, Berlin Heidelberg New York (Handbuch der medizinischen Radiologie, vol IX, 5 c)Google Scholar
  44. Zsebök Z (1958) Röntgenanatomie der Neugeborenen- und Säuglingslunge. Thieme, Stuttgart, p 118Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • E. Willich
  • E. Walter
  • W. R. Webb
  • G. de Geer

There are no affiliations available

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