Abstract
The objective of this paper is to discuss a new thesis concerning the sites of resistance to oxygen transport in red muscle in the steady state. Consideration will be given to both convective and diffusive transport [1] and the interaction between pathophysiology and these sites of resistance. Convective oxygen transport makes oxygen from the environment available for diffusive transport to the site of oxygen consumption (\( \dot{V}{{O}_{2}} \)), predominantly mitochondria in red muscle. The spatial distribution of resistances to diffusive O2 transport, the functions of myoglobin (Mb), the reserves of diffusive O2 transport in Mb-containing muscles and the distribution of mitochondria within the muscle determine the principal sites of resistance to diffusive transport.
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© 1991 Springer-Verlag Berlin Heidelberg
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Gayeski, T.E. (1991). Principal Determinants of Tissue PO2: Clinical Considerations. In: Gutierrez, G., Vincent, J.L. (eds) Tissue Oxygen Utilization. Update in Intensive Care and Emergency Medicine, vol 12. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84169-9_5
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DOI: https://doi.org/10.1007/978-3-642-84169-9_5
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