Abstract
Interstitial radiotherapy of early prostatic cancer with iodine-125 is an accepted treatment alternative for patients in which either radical operation or external beam irradiation is indicated. Pioneer work with this method has been done by Hilaris, Whitmore et al. since 1972 (Whitmore et al. 1972). Their therapeutic concept is based on the ideal radiation properties of iodine-125 as a low-energy γ-ray-emitting radionuclide with a long half-life. These characteristics provide for a sustained continuous irradiation of the tumor with a low dose to the adjacent tissues. Due to the low depth of penetration of the radiation, precise positioning of the seeds is a prerequisite for perfect dose distribition and good local tumor control.
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References
Bagshaw MA (1989) Stellenwert der Strahlentherapie in der Behandlung des Prostatakarzinoms. In: Sommerkamp H, Altwein JE (eds) Karger
Herr HW (1982) Pelvic lymphadenectomy and iodine-125 implantation. In: Johnson DE, Boileau MA (eds) Genitourinary tumors. Grune and Stratton, New York, pp 63–73
Holm HH, Juul N, Pedersen JF, Hansen H, Stroyer I (1983) Transperineal 125-iodine seed implantation in prostatic cancer guided by transrectal ultrasonography. J Urol 130: 283
Sommerkamp H (1986) Pelvic lymphadenectomy and brachytherapy for prostatic cancer: analysis of early postoperative morbidity. Eur Urol 12: 265–269
Sommerkamp H, Knüfermann H, WannenmacherM (1987) Grenzen der Strahlentherapie beim undifferenzierten Prostatakarzinom. II. Interstitielle Strahlentherapie. Tumordiagn Ther 8: 22–27
Sommerkamp H, Rupprecht M, Wannenmacher M (1988) Seed loss in interstitial radiotherapy of prostatic carcinoma with I-125. Int J Radiat Oncol Biol Phys 14: 389–392
Wannenmacher M, Sommerkamp H, Knüfermann, Kuphal K (1979) Die interstitielle Strahlentherapie in der Behandlung des Prostatakarzinoms. Dtsch Arztebl 76: 1371–1378
Whitmore WF, Hilaris B, Grabstald H (1972) Retropubic implantation of iodine 125 in the treatment of prostatic cancer. J Urol 108: 918–920
Whitmore WF Jr, Hilaris B, Batata M, Sogani P, Herr H, Morse M (1985) Interstitial radiation: short-term palliation or curative therapy? Urology [Suppl] 25: 24–29
Zincke H, Utz DC, Tuhle PM, Taylor WF (1987) Treatment options for patients with stage D1 (To-3, N1–2, Mo) adenocarcinoma of prostate. Urology 30: 307–315
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© 1991 Springer-Verlag Berlin Heidelberg
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Sommerkamp, H., Wannenmacher, M. (1991). Interstitial Radiotherapy: The Freiburg Experience. In: Sauer, R. (eds) Interventional Radiation Therapy. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84163-7_31
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DOI: https://doi.org/10.1007/978-3-642-84163-7_31
Publisher Name: Springer, Berlin, Heidelberg
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