Abstract
The control of transcription initiation is central among the mechanisms which regulate gene activity. In E. coli for example the rate of RNA synthesis directed by various promoters can differ by orders of magnitude. Moreover, the activity of an individual promoter may be modulated over a wide range by negatively and/or positively acting regulatory proteins. What are the principles which determine promoter activity and how can this activity be modified by regulatory proteins?
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Knaus, R., Bujard, H. (1990). Principles Governing the Activity of E. coli Promoters. In: Eckstein, F., Lilley, D.M.J. (eds) Nucleic Acids and Molecular Biology 4. Nucleic Acids and Molecular Biology, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84150-7_7
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DOI: https://doi.org/10.1007/978-3-642-84150-7_7
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