Abstract
Splenomegaly is the most prominent lesion observed in moribund animals. Hepatomegaly and generalized lymphadenopathy are also usually present. All three of these lesions may develop initially at approximately 6 months of age, and increase in magnitude and frequency as the anemia becomes increasingly severe (Creighton et al. 1979). The thymus may or may not be grossly prominent.
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Lewis, R.M., Picut, C.A. (1990). Autoimmune Hemolytic Anemia, NZB Mice. In: Jones, T.C., Ward, J.M., Mohr, U., Hunt, R.D. (eds) Hemopoietic System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84110-1_26
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DOI: https://doi.org/10.1007/978-3-642-84110-1_26
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