Abstract
Severe trauma is often complicated by the development of multiple organ system failure. In this context mainly dysfunction syndromes of lung and kidney have been described. Distinct disturbances of hepatic function have frequently been noticed. In some cases, however, severe liver failure is seen mostly in association with posttraumatic sepsis [7]. The pathomechanisms relating disturbances of hepatic blood flow, liver cell integrity, and the function of the reticuloendothelial system (RES) in the liver have so far not been clarified [1, 4, 10].
Supported by the DFG (Deutsche Forschungsgemeinschaft) project nr. TS 14/3-3 and 4
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Champion HR, Jones RT, Trump BF, et al. (1976) A clinicopathologic hepatic dysfunction following shock. Surg Gynecol Obstet 142:657–663
Gratz KF, Schober O, Schwarzrock R (1987) Nuklearmedizinische Untersuchungen in der Transplantatchirurgie. Nuklearmedizin 10:47–59
Kaku N (1987) Short-term and long-term changes in hepatic function in 60 patients with blunt liver injury. J Trauma 27:607–609
Kaplan JE, Saba TM (1976) Humoral deficiency and reticuloendothelial depression after traumatic shock. Am J Physiol 230:7–14
Mela L, Bacalzo LV, Miller LD (1971) Defective oxidative metabolism of rat liver mitochondria in hemorrhagic and endotoxin shock. Am J Physiol 220:571–577
Moyer E, Cerra F, Peters D, et al. (1981) Multiple systems organ failure. VI. Death predictors in the trauma-septic state - the most critical determinants. J Trauma 21:862–869
Norton L, Moore G, Eisenman R (1975) Liver failure in the postoperative patient: the role of sepsis and immunologic deficiency. Surgery, 78:6–13
Nunes G, Blaisdell FW, Margaretten W (1970) Mechanism of hepatic dysfunction following shock and trauma. Arch Surg 100:546–556
Rogers DE (1960) Host mechanisms which act to remove bacteria from the blood stream. Bacterial Rev 24:50–66
Scovill WA, Saba TM, Kaplan JE, et al. (1976) Deficits in reticuloendothelial humoral control mechanisms in patients after trauma. J Trauma 11:898–904
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Regel, G., Gratz, K.F., Pohlemann, T., Sturm, J.A., Tscherne, H. (1991). Changes in Reticuloendothelial Capacity Associated with Liver Dysfunction in Multiple Trauma. In: Sturm, J.A. (eds) Adult Respiratory Distress Syndrome. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84098-2_15
Download citation
DOI: https://doi.org/10.1007/978-3-642-84098-2_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-52180-8
Online ISBN: 978-3-642-84098-2
eBook Packages: Springer Book Archive