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Prospektive Studien von metastasierenden Prostatakarzinomen: 12 Jahre Erfahrung der urologischen Arbeitsgruppe der EORTC

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Book cover Behandlung des fortgeschrittenen Prostatakarzinoms

Zusammenfassung

Die urologische Arbeitsgruppe der EORTC hat in der onkologisch-urologischen Forschung über alle Aspekte des Prostatakarzinoms 12 Jahre Erfahrung. Die Gruppe hat insgesamt 5 Phase-II-Studien beendet, ein sechstes Protokoll ist z. Z. in Arbeit. Drei große randomisierte Studien über nicht vorbehandelte metastasierende Prostatakarzinome wurden abgeschlossen, 4 weitere Protokolle werden zur Zeit bearbeitet. Mehr als 1400 Patienten sind hieran beteiligt.

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Literatur

  • Benson RC, Gill GM, Cummings KB (1983) Randomised double blind crossover trial of Diethyl Stilboestrol (DES) and Estramustine Phosphate (EMCYT). The Stage D Prostatic Cancer. Semin Oncol 10 (Suppl 3): 43–45

    PubMed  Google Scholar 

  • Byar DP (1980) A review of the Veterans’ Administration Studies of Cancer of the Prostate: the new results concerning treatment of Stage I and II tumours. In: Pavone Macaluso M, Smith PH, Edsmyr S (eds) Bladder tumours and other topics in urological oncology. Plenum, New York London, pp 471–492

    Google Scholar 

  • De Voogd HJ, Smith PH, Pavone Macaluso M, de Pauw M, Suciu S, and Members of the European Organization for Research on Treatment of Cancer Urological Group (1986) Cardiovascular side effects of diethylstilbestrol, cyproterone acetate, medroxyprogesterone acetate and estramustine phosphate used for the treatment of advanced prostatic cancer: results from European Organization for Research on Treatment of Cancer trials 30761 and 30762. J Urol 135: 303–307

    Google Scholar 

  • Jones WG, Fossa SD, Denis L, Coninx P, Glashan RW, Akdas A, de Pauw M (1983) An EORTC phase II study of vindesine in advanced prostate cancer. Eur J Cancer 19: 583–588

    Article  CAS  Google Scholar 

  • Jones WG and members of the EORTC Genitourinary Cancer Cooperative Group (1984) EORTC Phase II Chemotherapy studies in prostate cancer. In: Denis L, Murphy GP, Prout GR, Schröder FH (eds) Controlled clinical trials in urologic oncology. Raven, New York, pp 181–185

    Google Scholar 

  • Jones WG, Bono AV, Verbaeys A, de Pauw M, Sylvester R, and members of the EORTC Genitourinary Tract Cancer Cooperative Group (1986a) Can the primary tumour be used as the sole parameter for response in phase II chemotherapy studies in metastatic prostate cancer? An EORTC Genitourinary Group report. World J Urol 4: 176–181

    Google Scholar 

  • Jones WG, Fossa SD, Bono AV, Croles JJ, Stoter G, de Pauw M, Slyvester R, and members of the EORTC Genitourinary Tract Cancer Cooperative Group (1986b) Mitomycin-C in the treatment of metastatic prostate cancer: report on an EORTC phase II study. World J Urol 4: 182–185

    Google Scholar 

  • Jones WG, Fossa SD, Bono AV, Klijn JMG, de Pauw M, Sylvester R (1987) European Organization for Research and Treatment of Cancer ( EORTC) phase II study of low-dose weekly epirubicin in metastatic prostate cancer. Cancer Treat Rep 71: 1317–1318

    PubMed  CAS  Google Scholar 

  • Pavone Macaluso M, Lund F, Mulder JH, Smith PH, de Pauw M, Sylvester R, and the EORTC Urological Group (1980) EORTC protocols in prostatic cancer. Scand J Urol Nephrol (Suppl) 55: 163–168

    CAS  Google Scholar 

  • Pavone Macaluso M, de Pauw M, Suciu S, Sylvester R, de Voogd HJ, Lardennois B, Nasta A, Zolfanelli R, Barasoldo E, and the EORTC Urological Group (1982) Medroxyprogesterone acetate, diethylstilboestrol and cyproterone acetate in the treatment of the prostatic cancer. Interim report of a prospective study of the European Organization for Research on the Treatment of Cancer (EORTC) Genito-urinary Tract Cooperative Group. Excerpta Medica International Series, pp 436–444

    Google Scholar 

  • Pavone Macaluso M and the EORTC Urological Group (1983) Medroxyprogesterone acetate in the treatment of prostatic cancer: preliminary results of EORTC trial 30761 comparing MPA with Stilbestrol and with Cyproterone Acetate. In: Campio L, Robustelli Della Cua G, Taylor RW (eds) Role of medroxyprogesterone in endocrine related tumors. Raven, New York, pp 183–190

    Google Scholar 

  • Pavone Macaluso M, de Voogd HJ, Viggiano G, Barasolo E, Lardennois B, de Pauw M, Sylvester R (1986) Diethylstilbestrol, cyproterone acetate and medroxyprogesterone acetate in the treatment of advanced prostatic cancer: final analysis of a randomised phase III trial of the European Organization for Research on Treatment of Cancer Urological Group. J Urol 136: 624–631

    CAS  Google Scholar 

  • Poyet P, Labrie F (1985) Comparison of the antiandrogenic/androgenic activities of flutamide, cyproterone acetate and megestrol acetate. Mol Cell Endocrinol 42: 283–288

    Article  PubMed  CAS  Google Scholar 

  • Robinson MRG, Hetherington J (1986) The EORTC studies: is there an optimal endocrine management for M1 prostatic cancer? World J Urol 4: 171–175

    Article  Google Scholar 

  • Schröder FH, and the EORTC Urological Group (1984) Treatment of prostatic cancer: EORTC experience–preliminary results of prostatic carcinoma trials. Prostate 5: 193–198

    Google Scholar 

  • Smith PH (1980) Medical management of prostatic cancer. Some current questions. Eur Urol 6: 65–68

    PubMed  CAS  Google Scholar 

  • Smith PH, Suciu S, Robinson MRG, Richards B, Bastable JRG, Glashan RW, Bouffioux C, Lardennois B, Williams RE, de Pauw M, Sylvester R (1986) A comparison of the effect of diethylstilbestrol with low dose estramustine phosphate in the treatment of advanced prostatic cancer: final analysis of a phase III trial of the European Organization for Research on Treatment of Cancer. J Urol 136: 619–623

    PubMed  CAS  Google Scholar 

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© 1990 Springer-Verlag Berlin Heidelberg

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Schröder, F.H., die urologische Arbeitsgruppe der EORTC. (1990). Prospektive Studien von metastasierenden Prostatakarzinomen: 12 Jahre Erfahrung der urologischen Arbeitsgruppe der EORTC. In: Frohmüller, H.G.W., Wirth, M.P. (eds) Behandlung des fortgeschrittenen Prostatakarzinoms. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84064-7_3

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  • DOI: https://doi.org/10.1007/978-3-642-84064-7_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-52076-4

  • Online ISBN: 978-3-642-84064-7

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