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Brain Failure pp 103–117Cite as

Pathophysiology of the Encephalopathies Associated with Uremia and Hyponatremia

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Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 9))

Abstract

Among patients with renal failure, nervous system dysfunction remains a major cause of disability. Depite the widespread use of dialysis therapy, such patients continue to manifest a variety of neurologic disorders [1]. Patients with chronic renal failure who have not yet received dialytic therapy may develop symptoms ranging from mild sensorial clouding to delirium and coma [2]. Even after the institution of adequate maintenance dialysis therapy, patients may continue to manifest more subtle nervous system dysfunction such as impaired mentation, generalized weakness, sexual dysfunction and peripheral neuropathy [3, 4].

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Authors
  1. C. L. Fraser
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  2. A. I. Arieff
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Editors and Affiliations

  1. Intensive Care Unit, Guy’s Hospital, St. Thomas Street, London, SE1 9RT, UK

    David Bihari

  2. Department of Neuropsychiatry, Walter Reed Army Institute of Research, Washington, DC, 20307, USA

    John W. Holaday

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© 1989 Springer-Verlag Berlin Heidelberg

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Fraser, C.L., Arieff, A.I. (1989). Pathophysiology of the Encephalopathies Associated with Uremia and Hyponatremia. In: Bihari, D., Holaday, J.W. (eds) Brain Failure. Update in Intensive Care and Emergency Medicine, vol 9. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83929-0_8

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  • DOI: https://doi.org/10.1007/978-3-642-83929-0_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-51655-2

  • Online ISBN: 978-3-642-83929-0

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