Cerebral Blood Flow in Head Injury
For the past 10 years it has been possible to measure cerebral blood flow (CBF) at the bedside in head-injured patients. Many clinical studies have been performed which have improved our understanding of the pathophysiological processes that occur after a severe head injury. These studies are complex and summarized in Table 1. Care must be taken when comparing results from different centers, as head injured patients do not form a homogeneous group with regard to age, mechanism and severity of injury. Differences in technique or in timing of CBF measurement after the acute event must be taken into account as well as the effects of different therapeutic regimens. Severe head injuries rarely occur in isolation; shock and hypoxia due to concomitant multiple trauma will be superimposed on the initial damage caused by the head injury.
KeywordsIschemia Lactate Dementia Pyruvate Bicarbonate
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